Abstract
Death of cells and fracture of the subchondral bone lead to collapse of the articular surface, all of which are caused by a compromised femoral head circulation. There is loss of the underlying structural framework of the diseased bone, which is resorbed by osteoclasts; when this occurs prior to revascularization and regeneration, the disease process could lead to joint involvement and arthritis. It frequently takes a relentless course that leads to a substantial loss of function and typically affects relatively young, active adults between the ages of 20 and 40. As a result, it is one of the most common reasons for hip replacement in the young to middle age population.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Lang P, Jergesen HE, Genant HK, Moseley ME, Schulte-Mönting J. Magnetic resonance imaging of the ischemic femoral head in pigs. Dependency of signal intensities and relaxation times on elapsed time. Clin Orthop Relat Res. 1989;(244):272–80.
Sugano N, Atsumi T, Ohzono K, Kubo T, Hotokebuchi T, Takaoka K. The 2001 revised criteria for diagnosis, classification, and staging of idiopathic osteonecrosis of the femoral head. J Orthop Sci. 2002;7:601–5.
Yuan HF, Guo CA, Yan ZQ. The use of bisphosphonate in the treatment of osteonecrosis of the femoral head: a meta-analysis of randomized control trials. Osteoporos Int. 2016;27:295–9.
Li D, Yang Z, Wei Z, Kang P. Efficacy of bisphosphonates in the treatment of femoral head osteonecrosis: a PRISMA-compliant meta-analysis of animal studies and clinical trials. Sci Rep. 2018;8:1450.
Agarwala S, Banavali SD, Vijayvargiya M. Bisphosphonate combination therapy in the management of postchemotherapy avascular necrosis of the femoral head in adolescents and young adults: a retrospective study from India. J Glob Oncol. 2018;4:1–11.
Osmani F, Thakkar S, Vigdorchik J. The utility of conservative treatment modalities in the management of osteonecrosis. Bull Hosp Jt Dis. 2013;2017(75):186–92.
Pritchett JW. Statin therapy decreases the risk of osteonecrosis in patients receiving steroids. Clin Orthop Relat Res. 2001;(386):173–8.
Song WS, Yoo JJ, Kim YM, Kim HJ. Results of multiple drilling compared with those of conventional methods of core decompression. Clin Orthop Relat Res. 2007;454:139–46.
Landgraeber S, Theysohn JM, Classen T, Jäger M, Warwas S, Hohn HP, et al. Advanced core decompression, a new treatment option of avascular necrosis of the femoral head—a first follow-up. J Tissue Eng Regen Med. 2013;7:893–900.
Fairbank AC, Bhatia D, Jinnah RH, Hungerford DS. Long-term results of core decompression for ischaemic necrosis of the femoral head. J Bone Joint Surg Br. 1995;77:42–9.
Yoon TR, Song EK, Rowe SM, Park CH. Failure after core decompression in osteonecrosis of the femoral head. Int Orthop. 2001;24:316–8.
Aggarwal AK, Poornalingam K, Jain A, Prakash M. Combining platelet-rich plasma instillation with core decompression improves functional outcome and delays progression in early-stage avascular necrosis of femoral head: a 4.5- to 6-year prospective randomized comparative study. J Arthroplasty. 2021;36:54–61.
Kumar P, Aggarwal S, Jindal K, Patel S, Sharma S, Mahan M. Core decompression combined with intraosseous ibandronate for pre-collapse osteonecrosis of the femoral head: report of a novel technique, its safety and early outcomes in five cases. J Orthop Case Rep. 2021;11:96–100.
Shuler MS, Rooks MD, Roberson JR. Porous tantalum implant in early osteonecrosis of the hip: preliminary report on operative, survival, and outcomes results. J Arthroplasty. 2007;22:26–31.
Murab S, Hawk T, Snyder A, Herold S, Totapally M, Whitlock PW. Tissue engineering strategies for treating avascular necrosis of the femoral head. Bioengineering (Basel). 2021;8(12):200.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Mehta, L., Dadra, A. (2023). Head Preservation: Recent Advances. In: Kumar, P., Aggarwal, S., Kumar, V. (eds) Insights into Avascular Necrosis of the Femoral Head . Springer, Singapore. https://doi.org/10.1007/978-981-99-1346-6_11
Download citation
DOI: https://doi.org/10.1007/978-981-99-1346-6_11
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-99-1345-9
Online ISBN: 978-981-99-1346-6
eBook Packages: MedicineMedicine (R0)