Abstract
Phytochemicals are widely assayed for their potent biological activities and successful findings have been reported. However, due to their poor water solubility and non-targeted site accumulation in addition to the diseased site, the potent of the phytochemicals is not at the desired level. In addition, quickly metabolized properties of the compounds are also critical obstacles in reaching the potent of the compound. In order to overcome the mentioned problem, flavonoids have been incorporated/loaded/encapsulated/conjugated to the nanomaterials as nano-carriers. Herewith in the chapter, we used VOSviewer software to reduce the dimension of the topics according to the networks constructed. The core and common flavonoid compounds were retrieved and used for literature reports and discussion section of the current chapter. In this regard, compounds such as hesperidin, rutin, quercetin, tannin/ tannic acid, naringin, naringenin, and kaemferol were reported. According to the in vivo and in vitro reports, flavonoid-mediated nanoparticles exhibited enhanced/higher activities with no appreciable toxic symptoms in comparison to the bare/pure compound or bare nanoparticle.
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Kulak, M., Gulmez Samsa, C. (2023). Flavonoids Mediated Nanomaterials Synthesis, Characterization, and Their Applications. In: Husen, A. (eds) Secondary Metabolites Based Green Synthesis of Nanomaterials and Their Applications. Smart Nanomaterials Technology. Springer, Singapore. https://doi.org/10.1007/978-981-99-0927-8_3
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