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Theranostic Applications of Functionalized Vesicular Carriers

Theranostic Applications of Functionalized Vesicular Carriers (Liposomes, Niosomes, Virosomes, Ethosomes, Phytosomes)

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Abstract

Metallic nanoparticles with therapeutic as well as diagnostic components have recently gained enormous attention in pharmaceutical research. The emergence of nanotechnology has put diagnosis and therapy closer to each other. By applying nanotechnology, many nanovesicular systems can be loaded with diagnostic and therapeutic moieties, called theranostic functionalized vesicular carriers, allowing the early detection of pathology and a targeted treatment. Targeted nanoparticles (NPs), nanovesicles (NVs), liposomes (LPs), and nanoclays for combined diagnosis and therapy have been extensively studied by researchers in the recent past. Diseases like breast cancer, hepatocellular carcinoma, neurodegenerative diseases, and cardiovascular diseases have been studied for the potential application of vesicular theranostic agents. Though the application of nanovesicle-based theranostic carriers is gaining attention, certain metallic nanovesicular system has been reported to be complicated in terms of designing, stability, and control of drug release, manufacturing at large scale, and has also been reported to have toxicity concern owing to their nanosizing, thus causing behavioral, physiological, and metabolic complications. In spite of limitations, numerous publications and patents are evident in last decades, indicating the acceptance of nanocarrier-based theranostic regime as an emerging science. Here in the present study, we have accumulated all the relevant information on theranostic attributes of functionalized vesicular carriers and also highlighted the limitations of its application to provide a window of further scientific exploration.

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Correspondence to Syed Sarim Imam .

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© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Jahangir, M.A., Mohanty, D., Choudhury, A., Imam, S.S. (2023). Theranostic Applications of Functionalized Vesicular Carriers. In: Jain, K., Jain, N.K. (eds) Multifunctional And Targeted Theranostic Nanomedicines. Springer, Singapore. https://doi.org/10.1007/978-981-99-0538-6_3

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  • DOI: https://doi.org/10.1007/978-981-99-0538-6_3

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-0537-9

  • Online ISBN: 978-981-99-0538-6

  • eBook Packages: MedicineMedicine (R0)

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