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Utilization of Natural Compounds for Treatment of Tuberculosis-I

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Medicinal Plants for Lung Diseases

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Abstract

Tuberculosis (TB) is a contagious infection caused by Mycobacterium tuberculosis. It is a highly communicable disease which affects the lungs but if left untreated can also spread to brain or spine. According to the World Health Organization, TB is considered as one of the top ten causes of death throughout the world with ten million cases reported annually. Although TB occurs in most parts of the world yet two thirds of the new cases reported, happened in India, China, Indonesia, Philippines, Pakistan, Nigeria, Bangladesh, and South Africa. TB is treated with a combination of antibiotics which has to be consumed by patients over a year or more. At present the drugs and vaccines available for treatment of TB has no significant effect on controlling the disease due to the occurrence of multiple drug-resistant (Mdr) strains. Hence, this created an urgent need to develop drugs of natural origin. Drugs from natural sources have exceptionally rich chemical diversity and a wide spectrum antimicrobial activity. The current chapter states the recent developments that had occurred in the treatment of TB using natural compounds and also discusses the various natural anti-mycobacterial compounds.

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Acknowledgement

Authors would like to acknowledge principal, Poona college of Pharmacy for his consistent encouragement, co-operation and suggestions.

Author information

Authors and Affiliations

  1. Chemical Engineering Department, National Institute of Technology Durgapur, Durgapur, West Bengal, India

    Madhumanti Mondal

  2. Development and Commercial, North America Thermo Fisher Scientific Pharma Services, Cincinnati, OH, USA

    Atmaram Pawar & Kaustuv Sahoo

  3. Department of Pharmaceutical Chemistry, Poona college of Pharmacy, Bharti VidyaPeeth University, Pune, India

    Atmaram Pawar, Kaustuv Sahoo & Dileep Kumar

Authors
  1. Madhumanti Mondal
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  2. Atmaram Pawar
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  3. Kaustuv Sahoo
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  4. Dileep Kumar
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Editor information

Editors and Affiliations

  1. Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, NSW, Australia

    Kamal Dua

  2. Discipline of Medical Sciences, School of Science, Western Sydney University, Sydney, NSW, Australia

    Srinivas Nammi

  3. NICM Health Research Institute, Western Sydney University, Sydney, NSW, Australia

    Dennis Chang

  4. Department of Life Sciences, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia

    Dinesh Kumar Chellappan

  5. School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India

    Gaurav Gupta

  6. Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia

    Trudi Collet

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Mondal, M., Pawar, A., Sahoo, K., Kumar, D. (2021). Utilization of Natural Compounds for Treatment of Tuberculosis-I. In: Dua, K., Nammi, S., Chang, D., Chellappan, D.K., Gupta, G., Collet, T. (eds) Medicinal Plants for Lung Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-33-6850-7_7

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