Abstract
Immuno-pathogenesis, by definition (Nature) is the process of disease development involving an immune response or components thereof. Our immune system comprises innate and adaptive systems. The innate immune system produces receptors that are hard-wired in our genome which encounters all types of pathogens. Innate immunity recognizes pathogen-related patterns known as pattern associated molecular patterns that enables it to distinguish pathogens from commensal organisms, acting as the first line of defense against pathogens. On the other hand, the adaptive immune system has specific receptors that are produced only when specific pathogens are encountered by the human body. Lymphocytes are an important component of the adaptive immunity as it can evolve and differentiate to recognize specific pathogens, protecting the body against subsequent infections. Although they are seen as separate, but both innate and adaptive immune systems work together, in which the former paves way for the latter for effectively providing long lasting immunity. Moreover, since there is a delay in the adaptive immune response (4 to 7 days), the innate immune response has a critical role in taking the lead to protect the body and/or controlling the spread of infection within the body. In this chapter, we will be describing the current findings of immuno-pathogenesis on various respiratory diseases.
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Madhavan, P., Rizwan, F., Shaik, I. (2021). Immuno-Pathogenesis of Respiratory Diseases. In: Dua, K., Nammi, S., Chang, D., Chellappan, D.K., Gupta, G., Collet, T. (eds) Medicinal Plants for Lung Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-33-6850-7_1
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