Abstract
Intensive search on sweetness of natural amino acids started after attaining success in synthesising artificial health friendly super sweet aspartame [1]. Consequently, the sweet natural amino acids identified so for [2, 3] are being re-examined with a hope of searching super sweet nutritive amino acids as the building block of body like that of carbohydrates.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Mazur, R.H, Gold kamp, A. H., Jasnes, PA. and schalatter, J.M. (1970). Structure – taste relationship of aspartic acid amide. J. med. Chem.. 6, 1217 – 1222.
Schiffman, S., and Dackis, C., (1975). Taste of nutrients: Amino acids, vitamins, and fatty acids. Perception & Psychophysics Vol. 17(2), 140-146.
Alexander, A., Bachmanov, N.P., Bosak, John I., Glendinning, M.I., Xia, Li, Satoshi, M., Stuart, A., Mc Caughey, Y., Murata, D. R. and Michael, G.T., (2016). Genetics of Amino Acid Taste and Appetite. Advance in Nutrition, 7, (4) 806S-822S.
Kornfeld, E. C., Suarez, T., Edie, R. Brannon, D. R., Fukuda, D, Sheneman, J., Todd, G. C. and Secondino, M. (1974) 6 – substituted tryptophans, a new class of potent synthetic sweetening agents, in Abstract of papers, American Chemical Society.
Vleggaar, R., Ackerman LG. J., and steyn, P.S., (1992). Structure elucidation of Monatin, a high intensity sweeteners isolated plant Schlerochiton ilicifolius. J. Chem. Soc. – Perkin Transation. 1: 3095 – 3098.
US application 20,050, 106,305 (https://worldwide.espacenet.com/textdoc?DB=EPODOC&IDX=US20,050,106,305), Timothy W. Abraham, Cargill.
O’Donnell K., Kearsley M., (2012) Sweeteners and Sugar Alternative in Food Technology, 2nd Edition, 201-203.
Daniells, S. (2012) cargill builds science for new high-intensity Monatin sweetener https://www.beveragedaily.com/Article/2012/09/04/cargill-builds-science-for-new-high-intensity-Monatin-sweetener .1-2.
Fry, J.C., yurttas, N, Biermanu, K.L., Lindley, M.G., and Goulson M.J. (2012). The sweetness concentration Response of R, R-Monatin, C. naturally occurring high potency sweetner. J. Food Sci. 77(10), S362-S364.
Amino, Y., Kawahara, S., Mori, K., Hirasawa, K., Sakata, H., Kashiwagi, T., (2016). Preparation and Characterization of Four Stereoisomers of Monatin. Chemical and Pharmaceutical Bulletin, 64 (8), 1161-1171.
“The Quest For a Natural Sugar Substitute,” Daniel Engber, The New York Times, 01 January (2014). [1] (https://www.nytimes.com/2014/01/05/magazine/the-quest-for-a-natural-sugar-substitute.html).
Funk A. Dickhaut, M. Geierhaas, D. and Hossain, R. (2016). Https://wwwchemic.tu-darmstadt.de/media/ak_ferssner/damocles_pdf/2016monatin_pdf.
Bassoli, A., Borgonovo, G., Busnelli, G., Morini, G. and Drew, M.G.B. (2005). Monatin and its stereoisomers: chemoenzymatic synthesis and taste properties Eur. J. Org. Chem., 2005 (8) (2005), pp. 1652-1658.
Nakamura K.; Baker T. J.; Goodman M.; Total Synthesis of Monatin; (2000); Org. Let.; Vol. 2, No. 19 2967-2970.
https://patentimages.storage.googleapis.com/WO2005014839A2/imgf000003_0001.png, 30.01.17.
Hlcks, P.M.; McFarlan, S.C.; US 8,440,434 B2, (2013).
Darpo, B., Bijornsson. TD., Brathwaite, WA., Crincoli, CM., Eapen, AK., Fisher, GL., Kowey, PR., Miller, MP., Nikiforov, Al., Rihner, MO., Zhou, M., 2016. Sweet flavoured isomer of a component first identified in root bark of selrochitin ilicifolius plant. Food Chem Toxicol. 91:217-24. doi: 10.1016.
Takakura, Y, Sugiyama M, Kawahara S., Mori, K 2017. Chemo-enzymatic hybrid process for production of monatin, a high intensity sweetener. Enzyme Engineering xxiv conference, 28 September, 2017.
Hlywka. J., Brathwait. W.A., Rihner, M.O., Nikiforov, A.I., Eapen, A.K. 2011. A 90-day oral (dietary) toxicity study of the 2R, 4R – isomer of monatin salt in Sparague-Dawley rats.
http://www.foodmanufacture.co.uk/Ingredients/PepsiCo-explores-natural-sweetener-from-oats, 30.01.17.
Mori K., Kawasaki; US 7,781,005 B2; (2010).
Archibald, E.A., Codd, L.E., Dyer, R.A., Meeuse, D.J., and van Druten, D. (1956). New and interesting records of South African flowering plants. R.A. Dyer (Ed.), Bothalia A Record of Contribution from the National Herbarium Union of South Africa Pretoria. The Government Printer, Pretoria (1956), pp. 535-547.
Peckover, R.G., (2018). A diabetic sweetener from the roots of Clerochiton ilicifolius, an indigenous shrub from northern and western parts of Southern Africa. PlantLife SA, 45:7.
Moengs, T.E. 2010 investigation in to the trade of medicinal plants by Muthi Shops and street vendors in the Limpopo Province of South Africa. Dissertation submitted for master degree Faculty of Sci. & Agric., university of Limpopo, S.A.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2022 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Dwivedi, R.S. (2022). Monatin: (Super Sweet Amino Acid). In: Alternative Sweet and Supersweet Principles . Springer, Singapore. https://doi.org/10.1007/978-981-33-6350-2_13
Download citation
DOI: https://doi.org/10.1007/978-981-33-6350-2_13
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-33-6349-6
Online ISBN: 978-981-33-6350-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)