Abstract
Initially, the super sweet characteristics of the rhizome of a widely distributed fern (Polypodium vulgare L.) was reported to be due to presence of glycyrrhizin in 1885 by Guignet [1]. However, after lapse of more than 8 decades, Herout and co-workers isolated the actual sweet principles present in P. vulgare as osladin, a steroidal saponin, in 1967 [2] and characterized that in 1971 [3]. The structural formula of osladin is presented in Fig. 12.1.
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References
Guignet, (1855) Quoted in Kim et al (1988). Polypodium A: An intensively sweet constituent of Polypodium glycyrrhiza. J. Nat. Prod. 51(6). 1166 – 1172.
Jizba J. and V. Herout, (1967) Isolation of constituents of common polypody rhizomes (Polypodium vulgare L.), Coll. Czech. Chem. Commun. 32:2867.
Jizba, J. Dolejs, V Herout & F Sorm (1971). The structure of osladin The sweet principle of the rhizomes of Polypodium vulgare L. dans Tetrahedron Lett., vol. 18, 1971, p. 1329 – 1332 doi:https://doi.org/10.1016/S0040-4039(01)96701-2.
Yamada, H. Nishizawa, M. and Katayama, C. (1992) 300 – 3000. Osladin. A sweet principle of Polypodium vulgare. Structure revision, Tetrahedron letters 33, 4009 – 4010.
Kinghorn A. D. and Soejarto, D. D. (1986). Sweetening agents of plant origin. Critical Rev. Plant Sci. 4(12), 79 – 120.
Yamada, H. und Nishizawa, M. (1995): Synthesis and Structure Revision of Intensely Sweet Saponin Osladin. In: J Org Chem. 60(2); 386 – 297; doi: https://doi.org/10.1021/jo00107a018.
Kim, J., Pezzuto, J. M., Soejarto, D.D., Lang, F. A., & Kinghorn, A. D. (1988). Polypodoside A., an intensely sweet constituent of Rhizome of Polypodium, glycyrrhiza. J. Nat. Prod. 51(6), 1166 – 1172.
Kinghorn, AD and Compadre, CM., (2001) Alternative Sweeteners: Third Edition, Revised and Expanded, Marcel Dekker, New York. ISBN 0 – 8247 – 0437 – 1.
Havel, M and Carny, V. (1975) Partial synthesis of osladin oglycone from solasodine. cou.czech.chem.commun.40.GoogleScholar.
Nishizawa M. and H. Yamada (1993). Synthesis of sweet tasting glycosides, story of osladin, Chemistry Today 60 (1993).
Nishizawa, M. and Yamada, H. (1996) Intensely sweet saponin osladin: Synthetic and structural study in saponins used in Food and Agriculture (eds) water and Yamasaki, plenurm press New York pp. 25 – 39.
Kim, N. C. and Kinghorn, A. D., (2002) Highly sweet compounds of plant origin. Arch. Pharm. Res. 25, 725 – 746.
Triska. Dr. Hamlyn Encyclopaedia of Plants. Hamlyn (1975) ISBN 0 – 600 – 335445 – 3.
Wiley Keith (2014 Dec 21) Desigining and Planting a wood land garden: Plants and combinations that thrive in shade. Google.Book.49/229pages.
F. Chittendon. RHS Dictionary of Plants plus Supplement. (1956) Oxford University Press 1951.
Ahmad Dar, P., Sofi, G. & Jafri, M. A., (2012). Polypodium vulgare Lin. Aversatile herbal medicin. A review Int. J. Pharm. Sci. Res. 3 (06), 1616-1620. ISSN:0975-8232.
Thomas. G. S. (1990) Plants for Ground Cover J. M. Dent & Sons 1990 ISBN 0 – 460 – 12609 – 1.
Shivas MG. (1961) Contribution to the cytology and taxonomy of species of Polypodium in Europe, and America. J. of the Linnean Soc. of Botany. 58 (370):13-25, 27-38.
Knight. F. P. (1980) Plants for Shade. Royal Horticultural Society. 1980 ISBN 0 – 099629 – 78 – 9.
Philips, R and Rix, M (1991). Perennials. Vol. 1 & 2 Pan Books-ISBN 0-330-30936-9.
Licorice fern (2020 May, 18) Staler Museum of Natural History (1930). University of Puget Sound-Tacoma, Washington (USA). (https://www/puget sound.edu)
Vesheka, O. (2016) Anatomical and morphological leaf trait of three evergreen ferns www.jstor.org>stable.
Moerman. D. (1998). Native American Ethnobotany. Timber Press. Oregon. 1998 ISBN 0 – 88192 – 435 – 9.
Brickell. C. (1990) The RHS Gardener’s Encyclopedia of Plants and Flowers Dorling Kindersley Publishers Ltd. 1990 ISBN 0 – 86318 – 386 – 7.
Huxley. A. (1992) The New RHS Dictionary of Gardening. 1992. MacMIllan Press 1992 ISBN 0 – 333 – 47494-5
Grieve. A (1984) Modern Herbal. Penguin 1984 ISBN 0 – 14 – 046 – 440 – 9.
Foster S. A Field (1990) Guide to Medicinal Plants. Houghton Mifflin, Boston 306.
Chopra. R. N., Nayar. S. L. and Chopra. I.C. (1986) Glossary of Indian Medicinal Plants (Including the Supplement). Council of Scientific and Industrial Research, New Delhi. 1986.
Chevallier. A. (1996) The Encyclopedia of Medicinal Plants Dorling Kindersley. London 1996 ISBN 9 – 780751 – 303148.
Mannan A, Khan RA, Asif M. (1989) Pharmacodynamic studies or Polypodium vulgare (Linn.). Indian Journal of Experimental Biology 1989, 27:556-560.
Duke JA, Ayensu ES. (1985) Medicinal Plants of China 4, Vol. 2 Reference Publications; Michigan 517-518.
Chiej R. (1988) The Macdonald Encyclopedia of Medicinal Plants Macdonald & Co, Verona 244.
Azam M.K. (1898) Mohit-e-Azam (persion). Nizami Press Lucknow, India 1898, 306-307.
Ghani N. Khaznatul-Advia, (1991) Vol-I, Nawal Kishore, Kanpur, India 1921, 266.
Ibn-Sina, (1948-99) AL-Qanun Fil-Tibb, (1948-99) Book-II, English translation. Jamia-Hamdard, 1998-99. New Delhi, India.
Baitar lbne Ziauddin Abu Mohammed. (1871) Jameul-Mufradat Aladvia-w-Aghzia, Azharia Press (Egypt) 1871, 94.
Husson GP, Vilagines R, Delaveau P. (1986) Recherche de Propriete Antivirales de quelques Extraits D’orgine Naturelle. Ann Pharmaceutiques Francaises 44: 41-48.
Fernald, M.L. (1922) Polypodium vurgenianum and Polypodium. Ir hodora J.
Ollgaard B, Tind K. (1993) Scandinavian Ferns. Rhodos, Aarhus 88-91.
Gadhiri, M.K. and Godji, A. (2004) A Review of impotance: Natural remedy for impotance in medival Persia. Int. J. Impotance Res. 16, 80-83.
Camp, F… and Mela, E. (1990) Ecdysteroid production in tissue culture of Polypodium vulgare Phytochemistry 29 (12), 3819-3821.
Polypodium vulgare A little fern with big benefits (2015, 5 March) Bold buck Nutrition (www.boldbuck.com)
Zhang, B, Sato, K and Yamamoto, D. (2018) Ecdysone signalling regulaters specification of neurons with male specific neurite in Drosophylla. Biol open 7 (2), bio. 029744.doi. 10-1242/bio. 029744
Krishnakumaran A, Schneiderman HA. (1968) Chemical control o moulting in arthropods. Nature 220: 601-603.
Schofield. J.E. (1989) Discovering Wild Plants – Alaska, W. Canada and the Northwest.
Deb Hanson (2016) Licorice fern-wondering around Oregon: wonderingaroundoregen. Wordpress.com.
Berch, Shannon (1988). “Mycorrhizal status of some plants of south western British Columbia”. Canadian Journal of Botany. 66 (10): 1924-1928. Doi: 10.1139/b88-263.
Chiej. R. (1984) Encyclopaedia of Medicinal Plants. MacDonald 1984 ISBN 0 – 356 – 10541 – 5.
Priya, Keerthi, Gupta, VRM, and Srikanth, K (2011). “Natural Sweeteners: A Complete Review”. Journal of Pharmacy Research. 4 (7), 2034-2039.
Turner. N. J. (1995) Food Plants of Coastal First Peoples UBC Press. Vancouver. 1995 ISBN 0 – 7748 – 0533 – 1.
Weiner. M. A. (1980) Earth Medicine, Earth Medicine, Earth Food. Ballantine Books 1980 ISBN 0 – 449 – 90589 – 6.
Foster. S. & Duke. J. A. (1990) A Field Guide to Medicinal Plants. Eastern and Central N. America. Houghton Mifflin Co. 1990 ISBN 0395467225.
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Dwivedi, R.S. (2022). Osladin, Polypodoside A, B and C (Steroidal Saponins). In: Alternative Sweet and Supersweet Principles . Springer, Singapore. https://doi.org/10.1007/978-981-33-6350-2_12
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