Skip to main content

Diagnostic Method and Instrumentation in Rhinology

  • Chapter
  • First Online:
Essentials of Rhinology

Abstract

Fungal rhinosinusitis is one of the major subtypes of chronic rhinosinusitis. It is classified into invasive and non-invasive types. Surgical clearance is the primary treatment method for non-invasive type. Non-invasive fungal sinusitis may convert into invasive type to some extent. The invasive is managed by debridement and long-term antifungal therapy. The prognosis of invasive type is poor than non-invasive type. Prophylactic, incomplete, and unnecessary prolong treatment raised the possibility of drug resistance. Proper identification of the causative organism, drug sensitivity against it, and treatment duration reduces the risk of relapse of disease and drug resistance which intern improves the quality of life. The correct diagnosis of the causative fungal organism is possible if the samples extract in correct way, timely transport to the laboratories, etc. New serological tests allow early identification of tissue invasion. Radiological interventions are commonly done for tissue diagnosis especially in hidden areas which require extensive exposure for biopsy such as high infratemporal fossa, cranial tumor eroding middle and posterior skull base. Interventions are also indicated to control traumatic bleeding and to reduce the vascularity of vascular lesions. The procedures are performed under image guidance in the head and neck region include those performed for obtaining diagnostic information or for therapeutic intent.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Chakrabarti A, Denning DW, Ferguson BJ, Ponikau J, Buzina W, Kita H, Marple B, Panda N, Vlaminck S, Kauffmann-Lacroix C, Das A, Singh P, Taj-Aldeen SJ, Kantarcioglu AS, Handa KK, Gupta A, Thungabathra M, Shivaprakash MR, Bal A, Fothergill A, Radotra BD. Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies. Laryngoscope. 2009;119(9):1809–18.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Callejas CA, Douglas RG. Fungal rhinosinusitis: what every allergist should know. Clin Exp Allergy. 2013;43(8):835–49.

    Article  CAS  PubMed  Google Scholar 

  3. Grosjean P, Weber R. Fungus balls of the paranasal sinuses: a review. Eur Arch Otorhinolaryngol. 2007;264(5):461–70.

    Article  PubMed  Google Scholar 

  4. Chakrabarti A, Rudramurthy SM, Panda N, Das A, Singh A. Epidemiology of chronic fungal rhinosinusitis in rural India. Mycoses. 2015;58(5):294–302.

    Article  PubMed  Google Scholar 

  5. Patterson TF, Thompson GR, Denning DW, et al. Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the infectious diseases society of America. Clin Infect Dis. 2016;63(4):e1–e60.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Cho HJ, Hong SD, Kim HY, Chung SK, Dhong HJ. Clinical implications of serum galactomannan measurement in patients with acute invasive fungal rhinosinusitis. Rhinology. 2016;54(4):336–41.

    Article  CAS  PubMed  Google Scholar 

  7. Theel ES, Doern CD. β-D-glucan testing is important for diagnosis of invasive fungal infections. J Clin Microbiol. 2013;51(11):3478–83.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Heldt S, Hoenigl M. Lateral flow assays for the diagnosis of invasive aspergillosis: current status. Curr Fungal Infect Rep. 2017;11(2):45–51.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Valero C, de la Cruz-Villar L, Zaragoza Ó, Buitrago MJ. New panfungal real-time PCR assay for diagnosis of invasive fungal infections. J Clin Microbiol. 2016;54(12):2910–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Arvanitis M, Anagnostou T, Fuchs BB, Caliendo AM, Mylonakis E. Molecular and nonmolecular diagnostic methods for invasive fungal infections. Clin Microbiol Rev. 2014;27(3):490–526.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Gupta S, Henningsen JA, Wallace MJ, Madoff DC, Morello FA, Ahrar K, et al. Percutaneous biopsy of head and neck lesions with CT guidance: various approaches and relevant anatomic and technical considerations. Radiogr Rev Publ Radiol Soc N Am Inc. 2007;27(2):371–90.

    Google Scholar 

  12. Kikuchi K, Yoshiura T, Hiwatashi A, Togao O, Yamashita K, Honda H. Balloon test occlusion of internal carotid artery: Angiographic findings predictive of results. World J Radiol. 2014;6(8):619–24.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Krajina A, Chrobok V. Radiological diagnosis and management of epistaxis. Cardiovasc Intervent Radiol. 2014;37(1):26–36.

    Article  PubMed  Google Scholar 

  14. Gandhi D, Gemmete JJ, Ansari SA, Gujar SK, Mukherji SK. Interventional neuroradiology of the head and neck. AJNR Am J Neuroradiol. 2008;29(10):1806–15.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Broomfield S, Bruce I, Birzgalis A, Herwadkar A. The expanding role of interventional radiology in head and neck surgery. J R Soc Med. 2009;102(6):228–34.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Kulkarni SS, Shetty NS, Dharia TP, Polnaya AM. Pictorial essay: Vascular interventions in extra cranial head and neck. Indian J Radiol Imaging. 2012;22(4):350–7.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Fayad LM, Carrino JA, Fishman EK. Musculoskeletal infection: role of CT in the emergency department. Radiographics. 2007;27:1723–1736 (Stacy GS, Kapur A (2011) Mimics of bone and soft tissue neoplasms. Radiol Clin N Am 49:1261–1286.

    Google Scholar 

  18. Mohandas A, Marcus C, Kang H, Truong M-T, Subramaniam RM. FDG PET/CT in the management of nasopharyngeal carcinoma. Am J Roentgenol. 2014;203(2):146–57.

    Article  Google Scholar 

  19. Kao CH, Hsieh JF, Tsai SC, et al. Comparison of 18-fluoro-2-deoxyglucose positron emission tomography and computed tomography in detection of cervical lymph node metastases of nasopharyngeal carcinoma. Ann Otol Rhinol Laryngol. 2000;109:1130–4.

    Article  CAS  PubMed  Google Scholar 

  20. Chong WH, Molinolo AA, Chen CC, Collins MT. Tumor-induced osteomalacia. Endocr Relat Cancer. 2011;18(3):R53–77. https://doi.org/10.1530/ERC-11-0006.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Cho K-S, Kang D-W, Kim H-J, Lee J-K, Roh H-J. Differential diagnosis of primary nasopharyngeal lymphoma and nasopharyngeal carcinoma focusing on CT, MRI, and PET/CT. Otolaryngol Head Neck Surg. 2012;146(4):574–8. https://doi.org/10.1177/019459981143471

    Article  PubMed  Google Scholar 

  22. Thompson L, Wieneke J, Miettinen M. Sinonasal tract and nasopharyngeal melanomas: a clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol. 2003;27:594–611.

    Article  PubMed  Google Scholar 

  23. Swetter S, Carroll L, Johnson D, Segall G. Positron emission tomography is superior to computed tomography for metastatic detection in melanoma patients. Ann Surg Oncol. 2002;9:646–53.

    Article  PubMed  Google Scholar 

  24. Goerres GW, Stoeckli SJ, von Schulthess GK, Steinert HC. FDG PET for mucosal malignant melanoma of the head and neck. Laryngoscope. 2002;112(2):381–5.

    Article  PubMed  Google Scholar 

  25. Howell MC, Branstetter BF, Snyderman CH. Patterns of regional spread for esthesioneuroblastoma. AJNR Am J Neuroradiol. 2011;32:929–33. https://doi.org/10.3174/ajnr.A2401.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Sasajima T, Kinouchi H, Tomura N, Watara J, Mizoi K. High uptake of 123I-metaiodobenzylguanidine related to olfactory neuroblastoma revealed by single-photon emission CT. Am J Neuroradiol. 2000;21(4):717–20.

    CAS  PubMed  PubMed Central  Google Scholar 

  27. Dublin AB, Bobinski M. Imaging characteristics of olfactory neuroblastoma (Esthesioneuroblastoma). J Neurol Surg B Skull Base. 2015;77(1):1–5.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Wu H-b, Wang Q-s, Zhong J-m, Zhou W-l, Li H-s, Qiao-yu W. Preliminary study on the evaluation of olfactory neuroblastoma using PET/CT. Clin Nucl Med. 2011;36:894–8.

    Article  PubMed  Google Scholar 

  29. Watanabe N, Nakanishi Y, Kinukawa N, et al. Expressions of somatostatin receptor subtypes (SSTR-1, 2, 3, 4 and 5) in neuroblastic tumors; special reference to clinicopathological correlations with international neuroblastoma pathology classification and outcomes. Acta Histochem Cytochem. 2014;47(5):219–29.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Savelli G, Bartolomei M, Bignardi M. Somatostatin receptors imaging and therapy in a patient affected by esthesioneuroblastoma with meningeal metastases. A classic example of theranostic approach. J Neurooncol. 2016;127:617–9. https://doi.org/10.1007/s11060-016-2067-3.

    Article  PubMed  Google Scholar 

  31. Pavlidis N, Briasoulis E, Hainsworth J, Greco FA. Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer. 2003;39(14):1990–2005.

    Article  CAS  PubMed  Google Scholar 

  32. Cianchetti M, Mancuso AA, Amdur RJ, Werning JW, Kirwan J, Morris CG, Mendenhall W. Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site. Laryngoscope. 2009;119(12):2348–54.

    Article  PubMed  Google Scholar 

  33. Calabrese L, Jereczek-Fossa BA, Jassem J, et al. Diagnosis and management of neck metastases from an unknown primary. Acta Otorhinolaryngol Ital. 2005;25(1):2–12.

    CAS  PubMed  PubMed Central  Google Scholar 

  34. Ross GL, Soutar DS. Sentinel node biopsy in head and neck cancer: preliminary results of a multicenter trial. Ann Surg Oncol. 2004;11:690–6.

    Article  PubMed  Google Scholar 

  35. Ene P, Popescu RC, Voiculescu S, et al. Sentinel lymph node — work hypothesis in sinonasal carcinoma treatment. Maedica (Buchar). 2011;6(4):308–12.

    Google Scholar 

  36. Scott B. In: Tille PM, editor. Bailey & Scott’s diagnostic microbiology. 13th ed: Elsevier Mosby; 2014.

    Google Scholar 

  37. Bennett JE, Dolin R, Blaser MJ, editors. Mandell: Mandell, Douglas and Bennett’s principles and practice of infectious diseases. 8th ed: Elsevier; 2015.

    Google Scholar 

  38. Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J (eds) Harrison: Harrison’s principles of internal medicine, 19th ed. McGraw Hill; 2015.

    Google Scholar 

  39. Garcia LS, Isenberg HD, editors. Isenberg: clinical microbiology procedural handbook. 2nd edition update. ASM Press; 2007.

    Google Scholar 

  40. Lee VS, Davis GE. Culture-directed topical antibiotic treatment for chronic rhinosinusitis. Am J Rhinol Allergy. 2016;30(6):414–7. https://doi.org/10.2500/ajra.2016.30.4380.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Rom D, Bassiouni A, Eykman E, et al. The association between disease severity and microbiome in chronic rhinosinusitis. Laryngoscope. 2019;129(6):1265–73. https://doi.org/10.1002/lary.27726.

    Article  PubMed  Google Scholar 

  42. Aring AM, Chan MM. Current concepts in adult acute rhinosinusitis. Am Fam Physician. 2016;94(2):97–105.

    PubMed  Google Scholar 

  43. Liu P, Lu L, Xu M, et al. A novel multiplex PCR for virus detection by melting curve analysis. J Virol Methods. 2018;262:56–60. https://doi.org/10.1016/j.jviromet.2018.09.010.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Chandra RK, Conley DB, Kern RC. Evolution of the endoscope and endoscopic sinus surgery. Otolaryngol Clin N Am. 2009;42(5):747–52.

    Article  Google Scholar 

  45. Marsh BR. Historic development of bronchoesophagology. Otolaryngol Head Neck Surg. 1996;114(6):689–716.

    CAS  PubMed  Google Scholar 

  46. Wootton C. Digital image formats, Chapter 6. In: A practical guide to video and audio compression: from sprockets and rasters to macro blocks. Burlington, MA: Focal Press; 2005. p. 115–46.

    Chapter  Google Scholar 

  47. Sindwani R, Manz R. Technological innovations in tissue removal during rhinologic surgery. Am J Rhino Allergy. 2012;26(1):65–9.

    Article  Google Scholar 

  48. Beswick DM, Rodriguez KD, Olds CE, et al. Quantification of maxillary sinus accessibility via a middle meatal antrostomy. Am J Rhinol Allergy. 2015;29(5):394–6.

    Article  PubMed  Google Scholar 

  49. Selivanova O, Kuehnemund M, Mann WJ, Amedee RG. Comparison of conventional instruments and mechanical debriders for surgery of patients with chronic sinusitis. Am J Rhinol. 2003;17(4):197–202.

    Article  PubMed  Google Scholar 

  50. Kumar N, Sindwani R. Bipolar microdebrider may reduce intraoperative blood loss and operative time during nasal polyp surgery. Ear Nose Throat J. 2012;91(8):336–44.

    Article  PubMed  Google Scholar 

  51. Grobler A, Carney AS. Radiofrequency coblation tonsillectomy. Br J Hosp Med (Lond). 2006;67(6):309–12.

    Article  Google Scholar 

  52. Coblation product brochure. https://www.smith-nephew.com/global/assets/pdf/products/surgical/sportsmedicine/08427f%20multi-electrode %20technology%20brochure.pdf. Accessed July 30, 2016.

  53. Sergeev VN, Belov SV. Coblation technology: a new method for high frequency electrosurgery. Biomed Eng. 2003;37(1):22–5.

    Article  Google Scholar 

  54. Belov SV. Use of high-frequency cold plasma ablation technology for electrosurgery with minimized invasiveness. Biomed Eng. 2004;38(2):80–5.

    Article  Google Scholar 

  55. Qi B, Ren C, Wang D, Li SZ, Wang K, Zhang Y. Uniform glow like plasma source assisted by preionization of spark in ambient air at atmospheric pressure. Appl Phys Lett. 2006;89:131503.

    Article  CAS  Google Scholar 

  56. Albritton FD, Kingdom TI, DelGaudio JM. Malleable registration mask: application of a novel registration method in image guided sinus surgery. Am J Rhinol. 2001;15:219–24.

    Article  CAS  PubMed  Google Scholar 

  57. Raabe A, Krishnan R, Wolff R, Hermann E, Zimmermann M, Seifert V. Laser surface scanning for patient registration in intracranial image-guided surgery. Neurosurgery. 2002;50:797–801. discussion 802–3

    Article  PubMed  Google Scholar 

  58. Azuma R, Bishop G. Improving static and dynamic registration in an optical see-through hmd. In: Proceedings of the 21st annual conference on computer graphics and interactive techniques. New York: ACM Press; 1994. p. 197–204.

    Google Scholar 

  59. Metson R. Image-guided sinus surgery: lessons learned from the first 1000 cases. Otolaryngol Head Neck Surg. 2003;128:8–13.

    Article  PubMed  Google Scholar 

  60. Neumann AM Jr, Pasquale-Niebles K, Bhuta T, Sillers MJ. Image-guided transnasal endoscopic surgery of the paranasal sinuses and anterior skull base. Am J Rhinol. 1999;13:449–54.

    Article  PubMed  Google Scholar 

  61. Chan KK, Watmough DJ, Hope DT, Moir K. A new motor-driven surgical probe and its in vitro comparison with the Cavitron Ultrasonic Surgical Aspirator. Ultrasound Med Biol. 1986;12:279–83.

    Article  CAS  PubMed  Google Scholar 

  62. Deppe G, Malviya VK, Malone JM Jr. Use of Cavitron Ultrasonic Surgical Aspirator (CUSA) for palliative resection of recurrent gynecologic malignancies involving the vagina. Eur J Gynaecol Oncol. 1989;10:1–2.

    CAS  PubMed  Google Scholar 

  63. Chopp RT, Shah BB, Addonizio JC. Use of ultrasonic surgical aspirator in renal surgery. Urology. 1983;22:157–9.

    Article  CAS  PubMed  Google Scholar 

  64. Gillams AR. The use of radiofrequency in cancer. Br J Cancer. 2005;92:1825–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  65. Gillams A. Tumor ablation: current role in the kidney, lung and bone. Cancer Imaging. 2009;9:68–70.

    Article  Google Scholar 

  66. Bilchik AJ, Rose DM, Allegra DP, Bostick PJ, Hsueh E, Morton DL. Radiofrequency ablation: a minimally invasive technique with multiple applications. Cancer J Sci Am. 1999;5:356–61.

    CAS  PubMed  Google Scholar 

  67. Lencioni R, Crocetti L, Cioni R, et al. Response to radiofrequency ablation of pulmonary tumours: a prospective, intention-to-treat, multicentre clinical trial (the RAPTURE study). Lancet Oncol. 2008;9:621–8.

    Article  PubMed  Google Scholar 

  68. Dupuy DE, Mayo-Smith WW, Abbott GF, DiPetrillo T. Clinical applications of radiofrequency tumor ablation in the thorax. Radiographics. 2002;22:259–69.

    Article  Google Scholar 

  69. Potera C. Forging a link between biofilms and disease. Science. 1999;283:1837–9.

    Article  CAS  PubMed  Google Scholar 

  70. Cavaliere R, Ball JL, Turnbull L, Whitchurch CB. The biofilm matrix destabilizers, EDTA and DNaseI, enhance the susceptibility of nontypeable Hemophilus influenzae biofilms to treatment with ampicillin and ciprofloxacin. Microbiology. 2014;3:557–67.

    Article  CAS  Google Scholar 

  71. Berlanga M, Gomez-Perez L, Guerrero R. Biofilm formation and antibiotic susceptibility in dispersed cells versus planktonic cells from clinical, industry and environmental origins. Antonie Van Leeuwenhoek. 2017;110:1691–704.

    Article  CAS  PubMed  Google Scholar 

  72. Valentine R, Jervis-Bardy J, Psaltis A, Tan LW, Wormald PJ. Efficacy of using a hydrodebrider and of citric acid/zwitterionic surfactant on a Staphylococcus aureus bacterial biofilm in the sheep model of rhinosinusitis. Am J Rhinol Allergy. 2011;25:323–6.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ripu Daman Arora .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Singh, G. et al. (2021). Diagnostic Method and Instrumentation in Rhinology. In: Verma, H., Thakar, A. (eds) Essentials of Rhinology. Springer, Singapore. https://doi.org/10.1007/978-981-33-6284-0_5

Download citation

  • DOI: https://doi.org/10.1007/978-981-33-6284-0_5

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-33-6283-3

  • Online ISBN: 978-981-33-6284-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics