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Bioinformatics for Human Microbiome

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Abstract

The dynamics of human metabolism and physiology is governed by the complex microbial communities present in different body sites. Advances in sequencing technologies and computational methods have boosted the microbiome analysis towards better resolution. Presently, microbiome research field has bloomed with generation of massive datasets and development of huge number of analysis tools. However, the complexity of the workflows and diversity of the tools in the repertoires make the field difficult. In this chapter we systematically discuss the metataxonomics, metagenomics and metatranscriptomics approaches, pipelines and the recommended tools. Further, the state-of-the-art downstream analysis techniques and visualisation tools were discussed. This chapter will help the researchers in computational analysis considering their biological questions related to human microbiome.

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Authors and Affiliations

  1. Division of Bioinformatics, Bose Institute, Kolkata, West Bengal, India

    Abhirupa Ghosh, Shazia Firdous & Sudipto Saha

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  1. Abhirupa Ghosh
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  2. Shazia Firdous
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  3. Sudipto Saha
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Editors and Affiliations

  1. Department of Biosciences, Indrashil University, Mehsana, Gujarat, India

    Vijai Singh

  2. Biotechnology, Rama University, Kanpur, Uttar Pradesh, India

    Ajay Kumar

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Ghosh, A., Firdous, S., Saha, S. (2021). Bioinformatics for Human Microbiome. In: Singh, V., Kumar, A. (eds) Advances in Bioinformatics. Springer, Singapore. https://doi.org/10.1007/978-981-33-6191-1_17

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