Abstract
Gout is characterized by painful joint inflammation due to the deposition of monosodium urate (MSU) crystals as a result of hyperuricemia. The disease spectrum ranges from acute inflammatory arthritis to chronic gout characterized by tophi. Diagnosis of gout is made by identification of MSU crystal in the joint fluid examination. Treatment of gout varies depending on the clinical spectrum of the disease. Acute gout is managed mostly by NSAIDs, colchicine, and steroids. Serum urate lowering agents like allopurinol and probenecid are used to reduce the serum uric acid level in chronic hyperuricemia. This chapter will discuss in detail about the management of gout according to the latest guidelines (American College of Rheumatology/European League against Rheumatism), the recent drugs approved, and drug in pipeline in various phase of clinical trials.
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Jayakumar, I. (2021). Pharmacotherapy of Gout. In: Paul, A., Anandabaskar, N., Mathaiyan, J., Raj, G.M. (eds) Introduction to Basics of Pharmacology and Toxicology. Springer, Singapore. https://doi.org/10.1007/978-981-33-6009-9_21
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DOI: https://doi.org/10.1007/978-981-33-6009-9_21
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