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Pre-existing Nutritional Deficiencies Associated with Obesity

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Management of Nutritional and Metabolic Complications of Bariatric Surgery

Abstract

Obesity is considered as a state of overnutrition as a result of excess calorie consumption over expenditure. However, the pre-operative nutritional status of individuals suffering from obesity suggests otherwise. Obesity is another spectrum of malnutrition due to multiple reasons, which include consumption of foods with empty calories, sedentary lifestyle, altered metabolism of nutrients, prolonged use of certain medications, food preferences, small intestinal bacterial overgrowth (SIBO) and obesity-associated inflammation. Deficiency of vitamin D, vitamin B12, haemoglobin, iron, folic acid and elevated PTH has been observed commonly in patients with clinically severe obesity, globally. This chapter highlights the need for pre-operative nutritional assessment and management of nutritional deficiencies. As the success of bariatric surgery relies on nutritional management both before and after the surgery.

We need a new definition of malnutrition. Malnutrition means- under and over nutrition. Malnutrition means emaciated and obese.

– Catherine Bertini

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References

  1. Tortora GJ, Derrickson BH. Principles of anatomy and physiology. Hoboken, NJ: Wiley; 2008.

    Google Scholar 

  2. www.who.int/mediacentre/factsheets/fs311/en/

  3. Dixit S, Zirpe K, Khatib K. Principles in critical care nutrition. New Delhi: Jaypee; 2019.

    Google Scholar 

  4. Carrodeguas L, Kaidar-Person O, Szomstein S, Antozzi P, Rosenthal R. Preoperative thiamine deficiency in obese population undergoing laparoscopic bariatric surgery. Surg Obes Relat Dis. 2005;1(6):517–22.

    Article  Google Scholar 

  5. Kaidar-Person O, Person B, Szomstein S, Rosenthal RJ. Nutritional deficiencies in morbidly obese patients: a new form of malnutrition? Obes Surg. 2008;18(7):870–6.

    Article  Google Scholar 

  6. Remedios C, Bhasker AG, Dhulla N, Dhar S, Lakdawala M. Bariatric nutrition guidelines for the Indian population. Obes Surg. 2016;26(5):1057–68.

    Article  Google Scholar 

  7. McClung JP, Karl JP. Iron deficiency and obesity: the contribution of inflammation and diminished iron absorption. Nutr Rev. 2009;67(2):100–4.

    Article  Google Scholar 

  8. Westerterp-Plantenga MS, Wijckmans-Duijsens NE, Verboeketvan de Venne WP, de GK, van het Hof KH, Weststrate JA. Energy intake and body weight effects of six months reduced or full fat diets, as a function of dietary restraint. Int J Obes Relat Metab Disord. 1998;22:14–22.

    Article  CAS  Google Scholar 

  9. Xanthakos SA. Nutritional deficiencies in obesity and after bariatric surgery. Pediatr Clin. 2009;56(5):1105–21.

    Google Scholar 

  10. Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Elevated C-reactive protein levels in overweight and obese adults. JAMA. 1999;282:2131–5.

    Article  CAS  Google Scholar 

  11. Damms-Machado A, Weser G, Bischoff SC. Micronutrient deficiency in obese subjects undergoing low calorie diet. Nutr J. 2012;11(1):34.

    Article  CAS  Google Scholar 

  12. Stein J, Stier C, Raab H, Weiner R. Review article: the nutritional and pharmacological consequences of obesity surgery. Aliment Pharmacol Ther. 2014;40(6):582–609.

    Article  CAS  Google Scholar 

  13. Roland BC, Lee D, Miller LS, Vegesna A, Yolken R, Severance E, et al. Obesity increases the risk of small intestinal bacterial overgrowth (SIBO). Neurogastroenterol Motil. 2018;30(3):e13199.

    Article  Google Scholar 

  14. Ley RE, Turnbaugh PJ, Klein S, ecology GJIM. human gut microbes associated with obesity. Nature. 2006;444:1022–3. https://doi.org/10.1038/4441022a.

    Article  CAS  PubMed  Google Scholar 

  15. Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006;444:1027–31. https://doi.org/10.1038/nature05414.

    Article  PubMed  Google Scholar 

  16. Sabaté JM, Jouët P, Harnois F, Mechler C, Msika S, Grossin M, Coffin B. High prevalence of small intestinal bacterial overgrowth in patients with morbid obesity: a contributor to severe hepatic steatosis. Obes Surg. 2008;18(4):371–7.

    Article  Google Scholar 

  17. Key TJ, Appleby PN, Rosell MS. Health effects of vegetarian and vegan diets. Proc Nutr Soc. 2006;65(1):35–41. https://doi.org/10.1079/PNS2005481.

    Article  CAS  PubMed  Google Scholar 

  18. Shridhar K, Dhillon PK, Bowen L, Kinra S, Bharathi AV, Prabhakaran D, et al. Nutritional profile of Indian vegetarian diets—the Indian Migration Study (IMS). Nutr J. 2014;13(1):55.

    Article  Google Scholar 

  19. Sherf-Dagan S, Hod K, Buch A, Mardy-Tilbor L, Regev Z, Ben-Porat T, et al. Health and nutritional status of vegetarian candidates for bariatric surgery and practical recommendations. Obes Surg. 2018;28(1):152–60.

    Article  Google Scholar 

  20. Waki M, Kral JG, Mazariegos M, Wang J, Pierson RN Jr, Heymsfield SB. Relative expansion of extracellular fluid in obese vs. nonobese women. Am J Physiol Endocrinol Metab. 1991;261(2):E199–203.

    Article  CAS  Google Scholar 

  21. Arshad M, Jaberian S, Pazouki A, Riazi S, Rangraz MA, Mokhber S. Iron deficiency anemia and megaloblastic anemia in obese patients. Rom J Intern Med. 2017;55(1):3–7.

    PubMed  Google Scholar 

  22. Cepeda-Lopez AC, Osendarp SJ, Melse-Boonstra A, Aeberli I, Gonzalez-Salazar F, Feskens E, et al. Sharply higher rates of iron deficiency in obese Mexican women and children are predicted by obesity-related inflammation rather than by differences in dietary iron intake. Am J Clin Nutr. 2011;93(5):975–83.

    Article  CAS  Google Scholar 

  23. Cepeda-Lopez AC, Aeberli I, Zimmermann MB. Does obesity increase risk for iron deficiency? A review of the literature and the potential mechanisms. Int J Vitam Nutr Res. 2010;80(4):263.

    Article  CAS  Google Scholar 

  24. Shah P, Chauhan AP. Impact of obesity on vitamin D and calcium status. Int J Med Res Rev. 2016;4(02).

    Google Scholar 

  25. Gebler L, Charuvastra M, Silver D. Nutritional deficiencies associated with obesity. J Obes Weight Loss Ther. 2015;5(252):2.

    Google Scholar 

  26. Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ. 2002;325:1202.

    Article  Google Scholar 

  27. Al-Mutawa A, Anderson A, Alsabah S, Al-Mutawa M. Nutritional status of bariatric surgery candidates. Nutrients. 2018;10(1):67.

    Article  Google Scholar 

  28. Mahan L, Escott-Stump S. Krause’s food nutrition therapy. 12th edn. St. Louis, MO: Saunders/Elsevier; 2008. p. 84–5, 414, 1229.

    Google Scholar 

  29. Gastaldi G, Casirola D, Ferrari G, Rindi G. Effect of chronic ethanol administration on thiamine transport in microvillous vesicles of rat small intestine. Alcohol Alcohol. 1989;24(2):83–9.

    Article  CAS  Google Scholar 

  30. Food and Nutrition Board. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B b6 s, folate, vitamin Bb12 s, pantothenic acid, biotin, and choline; Washington, DC: National Academy Press; 1998. p. 81, 182, 203–4, 211, 273.

    Google Scholar 

  31. Krzizek EC, Brix JM, Herz CT, Kopp HP, Schernthaner GH, Schernthaner G, Ludvik B. Prevalence of micronutrient deficiency in patients with morbid obesity before bariatric surgery. Obes Surg. 2018;28(3):643–8.

    Article  Google Scholar 

  32. Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, wson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr. 2006;84:18–28.

    Article  CAS  Google Scholar 

  33. Bhatti O, Bielefeldt KK, Nusrat S. Nutritional deficiencies in obesity and after weight reduction. Ann Nutr Disord Ther. 2015;2:1024–9.

    Google Scholar 

  34. Pereira S, Saboya C, Chaves G, Ramalho A. Class III obesity and its relationship with the nutritional status of vitamin A in pre-and postoperative gastric bypass. Obes Surg. 2009;19(6):738–44.

    Article  Google Scholar 

  35. Ernst B, Thurnheer M, Schmid SM, Schultes B. Evidence for the necessity to systematically assess micronutrient status prior to bariatric surgery. Obes Surg. 2009;19(1):66–73.

    Article  Google Scholar 

  36. Yuyama LKO, Yonekura L, Aguiar JPL, Rodrigues MLCF, Cozzolino SMF. Zinco. In: Cozzolino SMF, editor. Biodisponibilidade de Nutrientes, 3th edn. Barueri: Manole. p. 616–43.

    Google Scholar 

  37. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266–81, 24.

    Article  CAS  Google Scholar 

  38. Chakravarty PK, Ghosh A, Chowdhury JR. Zinc in human malignancies. Neoplasma. 1986;85–90(27):33.

    Google Scholar 

  39. Guy NC, Garewal H, Holubec H, et al. A novel dietary-related model of esophagitis and Barrett’s esophagus, a premalignant lesion. Nutr Cancer. 2007;59:217–27.

    Article  CAS  Google Scholar 

  40. Stamoulis I, Kouraklis G, Theocharis S. Zinc and the liver: an active interaction. Dig Dis Sci. 2007;52:1595–612.

    Article  CAS  Google Scholar 

  41. Shankar P, Boylan M, Sriram K. Micronutrient deficiencies after bariatric surgery. Nutrition (Burbank, Los Angeles County, Calif). 2010;26(11–12):1031–7.

    Article  CAS  Google Scholar 

  42. Parrott J, Frank L, Rabena R, et al. American Society for Metabolic and Bariatric Surgery integrated health nutritional guidelines for the surgical weight loss patient, 2016 update: micronutrients. Surg Obes Relat Dis. 2017;13(5):727–41.

    Article  Google Scholar 

  43. Gudzune KA, Huizinga MM, Chang H-Y, et al. Screening and diagnosis of micronutrient deficiencies before and after bariatric surgery. Obes Surg. 2013;23(10):1581–9.

    Article  Google Scholar 

  44. Flancbaum L, Belsley S, Drake V, Colarusso T, Tayler E. Preoperative nutritional status of patients undergoing Roux-en-Y gastric bypass for morbid obesity. J Gastrointest Surg. 2006;10(7):1033–7.

    Article  Google Scholar 

  45. Moizé V, Deulofeu R, Torres F, de Osaba JM, Vidal J. Nutritional intake and prevalence of nutritional deficiencies prior to surgery in a Spanish morbidly obese population. Obes Surg. 2011;21(9):1382–8.

    Article  Google Scholar 

  46. Sánchez A, Rojas P, Basfi-fer K, Carrasco F, Inostroza J, Codoceo J, et al. Micronutrient deficiencies in morbidly obese women prior to bariatric surgery. Obes Surg. 2016;26(2):361–8.

    Article  Google Scholar 

  47. Schweiger C, Weiss R, Berry E, Keidar A. Nutritional deficiencies in bariatric surgery candidates. Obes Surg. 2010;20(2):193–7.

    Article  Google Scholar 

  48. Lee PC, Ganguly S, Dixon JB, Tan HC, Lim CH, Tham KW. Nutritional deficiencies in severe obesity: a multiethnic Asian Cohort. Obes Surg. 2019;29(1):166–71.

    Article  Google Scholar 

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Lakdawala, M., Sancheti, M.S., Kantharia, N., Bhasker, A.G. (2021). Pre-existing Nutritional Deficiencies Associated with Obesity. In: Bhasker, A.G., Kantharia, N., Baig, S., Priya, P., Lakdawala, M., Sancheti, M.S. (eds) Management of Nutritional and Metabolic Complications of Bariatric Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-33-4702-1_3

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  • DOI: https://doi.org/10.1007/978-981-33-4702-1_3

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