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Ophthalmological Complications After Bariatric Surgery

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Management of Nutritional and Metabolic Complications of Bariatric Surgery

Abstract

While bariatric surgery confers significant weight reduction and control of metabolic diseases, its effect on diabetic retinopathy (DR) and other eye-related conditions remain a topic of much debate. Studies have shown conflicting results with regards to eye health in general following bariatric surgery, with reports of diabetic retinopathy improvement on one hand versus ophthalmological complications such as early worsening of diabetic retinopathy (EWDR), nyctalopia, xerosis, corneal ulceration, and permanent blindness on the other. Prolonged uncontrolled diabetes, the paradoxical effect of sudden significant reduction of blood glucose in the immediate hours following bariatric surgery, nutritional deficiency, and hypovitaminosis have all been cited as plausible causes for visual impairment in patients having undergone bariatric surgery. Efforts undertaken to identify and prevent deterioration of sight following bariatric surgery should be a concerted one with the involvement of ophthalmologist as part of the multidisciplinary team especially in patients with underlying metabolic syndrome or known ocular problems. It is equally imperative that emphasis is placed on patient education as well to reduce the risk of ophthalmic complications that could arise due to lack of compliance to follow-up or non-adherence to vitamin supplementation following surgery.

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References

  1. Gloy VL, et al. Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials. BMJ. 2013;347:f5934.

    Article  Google Scholar 

  2. Ribaric G, et al. Diabetes and weight in comparative studies of bariatric surgery vs conventional medical therapy: a systematic review and meta-analysis. Obes Surg. 2014;24:437–55.

    Article  CAS  Google Scholar 

  3. Cheung N, et al. Diabetic retinopathy. Lancet. 2010;376(9735):124–36.

    Article  Google Scholar 

  4. Yau JW, et al. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012;35(3):556–64.

    Article  Google Scholar 

  5. Xu J, et al. Ten-year cumulative incidence of diabetic retinopathy. The Beijing Eye Study 2001/2011. PLoS One. 2014;9(10):e111320.

    Article  Google Scholar 

  6. Jin P, et al. The 5-year onset and regression of diabetic retinopathy in Chinese type 2 diabetes patients. PLoS One. 2014;9(11):e113359.

    Article  Google Scholar 

  7. Kajiwara A, et al. Gender differences in the incidence and progression of diabetic retinopathy among Japanese patients with type 2 diabetes mellitus: a clinic-based retrospective longitudinal study. Diabetes Res Clin Pract. 2014;103(3):e7–10.

    Article  CAS  Google Scholar 

  8. Salinero-Fort MA, et al. Four-year incidence of diabetic retinopathy in a Spanish cohort: the MADIABETES study. PLoS One. 2013;8(10):e76417.

    Article  CAS  Google Scholar 

  9. Silva RA, et al. Severe worsening of diabetic retinopathy following bariatric surgery. Ophthalmic Surg Laser Imag Retina. 2013;44 Online(6):E11-4.

    Google Scholar 

  10. Chen Y, et al. Does bariatric surgery prevent progression of diabetic retinopathy? Eye. 2017;31:1131–9.

    Article  CAS  Google Scholar 

  11. van Ballegooie E, et al. Rapid deterioration of diabetic retinopathy during treatment with continuous subcutaneous insulin infusion. Diabetes Care. 1984;7:236–42.

    Article  Google Scholar 

  12. Lauritzen T, et al. Effect of 1 year of near-normal blood glucose levels on retinopathy in insulin-dependent diabetics. Lancet. 1983;1:200–4.

    Article  CAS  Google Scholar 

  13. Dahl-Jørgensen K, et al. Rapid tightening of blood glucose control leads to transient deterioration of retinopathy in insulin dependent diabetes mellitus: the Oslo study. Br Med J (Clin Res Ed). 1985;290:811–5.

    Article  Google Scholar 

  14. Kowluru RA. Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats. Diabetes. 2003;52(3):818–23.

    Article  CAS  Google Scholar 

  15. Varadhan L, et al. Bariatric surgery and diabetic retinopathy: a pilot analysis. Obes Surg. 2012;22:515–6.

    Article  Google Scholar 

  16. Miras AD, et al. Type 2 diabetes mellitus and microvascular complications 1 year after Roux-en-Y gastric bypass: a case-control study. Diabetologia. 2015;58:1443–7.

    Article  CAS  Google Scholar 

  17. Schauer PR, et al. Bariatric surgery versus intensive medical therapy for diabetes – 3-year outcomes. N Engl J Med. 2014;370:2002–13.

    Article  Google Scholar 

  18. Singh RP, et al. Effect of bariatric surgery versus intensive medical management on diabetic ophthalmic outcomes. Diabetes Care. 2015;38:e32–3.

    Article  Google Scholar 

  19. Thomas RL, et al. Does bariatric surgery adversely impact on diabetic retinopathy in persons with morbid obesity and type 2 diabetes? A pilot study. J Diabetes Complications. 2014;28:191–5.

    Article  Google Scholar 

  20. Cheung D, et al. The impact of bariatric surgery on diabetic retinopathy: a systematic review and metaanalysis. Obes Surg. 2015;25:1604–9.

    Article  Google Scholar 

  21. Murphy R, et al. Progression of diabetic retinopathy after bariatric surgery. Diabet Med. 2015;32:1212–20.

    Article  CAS  Google Scholar 

  22. Pontiroli AE, Ceriani V. Does bariatric surgery influence diabetic retinopathy? Obesity surgery. 2015;25(6):1066.

    Article  Google Scholar 

  23. Amin AM, et al. The impact of bariatric surgery on retinopathy in patients with type 2 diabetes: a retrospective cohort study. Surg Obes Relat Dis. 2016;12:606–12.

    Article  Google Scholar 

  24. Feldman-Billard S, et al. Early worsening of diabetic retinopathy after rapid improvement of blood glucose control in patients with diabetes. Diabetes Metab. 2018;44(1):4–14.

    Article  CAS  Google Scholar 

  25. Wilkinson CP, et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003;110(9):1677–82.

    Article  CAS  Google Scholar 

  26. Shankar P, et al. Micronutrient deficiencies after bariatric surgery. Nutrition. 2010;26(11–12):1031–7.

    Article  CAS  Google Scholar 

  27. Parrish CR. Severe micronutrient deficiencies in RYGB patients: rare but potentially devastating. Pract Gastroenterol. 2011;100:13–27.

    Google Scholar 

  28. Rino Y, et al. Vitamin E deficiency begins within 6 months after gastrectomy for gastric cancer. World J Surg. 2014.

    Google Scholar 

  29. Naismith RT, et al. Acute and bilateral blindness due to optic neuropathy associated with copper deficiency. Arch Neurol. 2009;66(8):1025–7.

    Article  Google Scholar 

  30. Pineles SL, et al. Combined optic neuropathy and myelopathy secondary to copper deficiency. Surv Ophthalmol. 2010;55(4):386–92.

    Article  Google Scholar 

  31. Slater GH, et al. Serum fat-soluble vitamin deficiency and abnormal calcium metabolism after malabsorptive bariatric surgery. J Gastrointest Surg. 2004;8:48–55.

    Article  Google Scholar 

  32. Scopinaro N, et al. Biliopancreatic diversion. World J Surg. 1998;22(9):936–46.

    Article  CAS  Google Scholar 

  33. Lee WB, et al. Ocular complications of hypovitaminosis A after bariatric surgery. Ophthalmology. 2005;112(6):1031–4.

    Article  Google Scholar 

  34. Chaves GV, et al. Association between liver vitamin A reserves and severity of nonalcoholic fatty liver disease in the class III obese following bariatric surgery. Obes Surg. 2014;24(2):219–24.

    Article  Google Scholar 

  35. Zalesin KC, et al. Vitamin a deficiency after gastric bypass surgery: an underreported postoperative complication. J Obes. 2011;2011.

    Google Scholar 

  36. de Pee S, Dary O. Biochemical indicators of vitamin A deficiency: serum retinol and serum retinol binding protein. J Nutr. 2002;132(9 Suppl):2895S–01.

    Article  Google Scholar 

  37. Guerreiro RA, Rui R. Ophthalmic complications of bariatric surgery. Obes Surg. 2015;25(1):167–73.

    Article  Google Scholar 

  38. Allied Health Sciences Section Ad Hoc Nutrition Committee, Aills L, Blankenship J, et al. ASMBS allied health nutritional guidelines for the surgical weight loss patient. Surg Obes Relat Dis. 2008;4(5 Suppl):S73–108.

    Google Scholar 

  39. Thomson AD, Marshall EJ. The natural history and pathophysiology of Wernicke’s encephalopathy and Korsakoff’s psychosis. Alcohol Alcohol. 2006;41(2):151–8.

    Article  CAS  Google Scholar 

  40. Singh S, Kumar A. Wernicke encephalopathy after obesity surgery: a systematic review. Neurology. 2007;68:807–11.

    Article  Google Scholar 

  41. Aslam A, Misbah SA, Talbot K, Chapel H. Vitamin E deficiency induced neurological disease in common variable immunodeficiency: two cases and a review of the literature of vitamin E deficiency. Clin Immunol. 2004;112(1):24–9.

    Article  CAS  Google Scholar 

  42. Moss HE. Bariatric surgery and the neuro-ophthalmologist. J Neuro-Ophthalmol. 2016;36(1):78.

    Article  Google Scholar 

  43. Shah AR, Tamhankar MA. Optic neuropathy associated with copper deficiency after gastric bypass surgery. Retinal Cases Brief Rep. 2014;8(1):73–6.

    Article  Google Scholar 

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Teh, WM., Tan, PH., Rajan, R. (2021). Ophthalmological Complications After Bariatric Surgery. In: Bhasker, A.G., Kantharia, N., Baig, S., Priya, P., Lakdawala, M., Sancheti, M.S. (eds) Management of Nutritional and Metabolic Complications of Bariatric Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-33-4702-1_17

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  • DOI: https://doi.org/10.1007/978-981-33-4702-1_17

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