Skip to main content

Multi-task Data Driven Modelling Based on Transfer Learned Features in Deep Learning for Biomedical Application

  • Conference paper
  • First Online:
Innovations in Computer Science and Engineering

Abstract

Accurate automatic Identification and localization of spine vertebrae points in CT scan images is crucial in medical diagnosis. This paper presents an automatic feature extraction network, based on transfer learned CNN, in order to handle the availability of limited samples. The 3D vertebrae centroids are identified and localized by an LSTM network, which is trained on CNN features extracted from 242 CT spine sequences. The model is further trained to estimate age and gender from LSTM features. Thus, we present a framework that serves as a multi-task data driven model for identifying and localizing spine vertebrae points, age estimation and gender classification. The proposed approach is compared with benchmark results obtained by testing 60 scans. The advantage of the multi-task framework is that it does not need any additional information other than the annotations on the spine images indicating the presence of vertebrae points.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 219.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 279.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. http://csi-workshop.weebly.com/challenges.html

  2. Bowles, C., Chen, L., Guerrero, R., Bentley, P., Gunn, R., Hammers, A., Dickie, D.A., Hernández, M.V., Wardlaw, J., Rueckert, D.: GAN augmentation: augmenting training data using generative adversarial networks. arXiv preprint arXiv:1810.10863 (2018)

  3. Chen, H., Shen, C., Qin, J., Ni, D., Shi, L., Cheng, J.C., Heng, P.A.: Automatic localization and identification of vertebrae in spine CT via a joint learning model with deep neural networks. In: International Conference on Medical Image Computing and Computer-Assisted Intervention, pp. 515–522. Springer (2015)

    Google Scholar 

  4. Cutler, A., Cutler, D.R., Stevens, J.R.: Random forests. In: Ensemble Machine Learning, pp. 157–175. Springer (2012)

    Google Scholar 

  5. Frid-Adar, M., Diamant, I., Klang, E., Amitai, M., Goldberger, J., Greenspan, H.: GAN-based synthetic medical image augmentation for increased CNN performance in liver lesion classification. Neurocomputing 321, 321–331 (2018)

    Article  Google Scholar 

  6. Glocker, B., Zikic, D., Konukoglu, E., Haynor, D.R., Criminisi, A.: Vertebrae localization in pathological spine CT via dense classification from sparse annotations. In: International Conference on Medical Image Computing and Computer-Assisted Intervention, pp. 262–270. Springer (2013)

    Google Scholar 

  7. Goodfellow, I., Pouget-Abadie, J., Mirza, M., Xu, B., Warde-Farley, D., Ozair, S., Courville, A., Bengio, Y.: Generative adversarial nets. In: Advances in Neural Information Processing Systems, pp. 2672–2680 (2014)

    Google Scholar 

  8. Hon, M., Khan, N.M.: Towards Alzheimer’s disease classification through transfer learning. In: 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), pp. 1166–1169. IEEE (2017)

    Google Scholar 

  9. Hussain, Z., Gimenez, F., Yi, D., Rubin, D.: Differential data augmentation techniques for medical imaging classification tasks. In: AMIA Annual Symposium Proceedings. vol. 2017, p. 979. American Medical Informatics Association (2017)

    Google Scholar 

  10. Kwasigroch, A., Mikołajczyk, A., Grochowski, M.: Deep neural networks approach to skin lesions classification—a comparative analysis. In: 2017 22nd International Conference on Methods and Models in Automation and Robotics (MMAR), pp. 1069–1074. IEEE (2017)

    Google Scholar 

  11. Liao, H., Mesfin, A., Luo, J.: Joint vertebrae identification and localization in spinal CT images by combining short- and long-range contextual information. IEEE Trans. Med. Imaging 37(5), 1266–1275 (2018)

    Article  Google Scholar 

  12. Schmidt, S., Kappes, J., Bergtholdt, M., Pekar, V., Dries, S., Bystrov, D., Schnörr, C.: Spine detection and labeling using a parts-based graphical model. In: Biennial International Conference on Information Processing in Medical Imaging, pp. 122–133. Springer (2007)

    Google Scholar 

  13. Van Opbroek, A., Ikram, M.A., Vernooij, M.W., De Bruijne, M.: Transfer learning improves supervised image segmentation across imaging protocols. IEEE Trans. Med. Imaging 34(5), 1018–1030 (2014)

    Article  Google Scholar 

  14. Wang, X., Zhai, S., Niu, Y.: Automatic vertebrae localization and identification by combining deep SSAE contextual features and structured regression forest. J. Digit. Imaging 32(2), 336–348 (2019)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to N. Harini .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Harini, N. et al. (2021). Multi-task Data Driven Modelling Based on Transfer Learned Features in Deep Learning for Biomedical Application. In: Saini, H.S., Sayal, R., Govardhan, A., Buyya, R. (eds) Innovations in Computer Science and Engineering. Lecture Notes in Networks and Systems, vol 171. Springer, Singapore. https://doi.org/10.1007/978-981-33-4543-0_20

Download citation

Publish with us

Policies and ethics