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Translational Research in Surgical Oncology: Introduction and My Own Experience as a Surgeon-Scientist

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Book cover Translational Research in Breast Cancer

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1187))

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Abstract

Translational research is possible when scientists have broad knowledge of not only basic research, but also clinical science, which is acquired via experience in patient care. These requirements cannot always be met by one individual, and, hence, collaboration between suitably qualified individuals is the key for the progress of translational research. However, it is vital that translational research is conducted by an investigator who has knowledge about all fields. I could be a good conductor in that sense, because as an oncology surgeon, I have considerable experience in working with patients; in addition, I have a background in biochemistry and have started my basic research laboratory. Thus, I can use these qualifications to my advantage to build a tissue bank as the first step, and initiate small-scale experiments such as estimating the DNA or protein levels in specific tissues or blood samples. Once I successfully launch good research products and publish in peer-reviewed journals, I intend to build a large research group focusing on large-scale studies on single nucleotide polymorphisms and proteomics. These translational approaches can overcome several unsolved clinical problems. Many of my research products, for example, patents and new techniques such as Mastocheck@, are designed for improving the clinical outcomes in patients.

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Acknowledgments

I acknowledge Ms. Minjung Kim (Bioinformatics Laboratory, SNU) for summarizing my publications on SNP. I also thank Dr. Yumi Kim (SNUH) for the illustrations and updates on Mastocheck@. I thank Mr. Sangwoo Kim (Imperial College, London) for correcting the English. I also thank Dr. Hong Kyu Kim (SNUH) for collecting and editing entire chapters.

Conflict of Interest

Noh DY has a stock-option for Bertis Inc.

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Authors and Affiliations

  1. Department of Surgery, College of Medicine, Seoul National University, Seoul, South Korea

    Dong-Young Noh

  2. Gangnam CHA Medical Center, Seoul, South Korea

    Dong-Young Noh

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  1. Dong-Young Noh
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Correspondence to Dong-Young Noh .

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Editors and Affiliations

  1. Department of Surgery, College of Medicine, Seoul National University, Seoul, Korea (Republic of)

    Dong-Young Noh

  2. College of Medicine, Seoul National University College of Medicine, Seoul, Korea (Republic of)

    Wonshik Han

  3. Graduate School of Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Masakazu Toi

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Noh, DY. (2021). Translational Research in Surgical Oncology: Introduction and My Own Experience as a Surgeon-Scientist. In: Noh, DY., Han, W., Toi, M. (eds) Translational Research in Breast Cancer. Advances in Experimental Medicine and Biology, vol 1187. Springer, Singapore. https://doi.org/10.1007/978-981-32-9620-6_1

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