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Biological Evaluation of Slip Casting Hydroxyapatite Intended for Cranioplasty

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3rd International Conference on Nanotechnologies and Biomedical Engineering

Part of the book series: IFMBE Proceedings ((IFMBE,volume 55))

Abstract

In this paper are presented the results obtained for biocompatibility tests on some cranial implant synthetic models destined for using in skull bone surgery applications. The samples were made of hydroxyapatite (HAp) powders and shaped by slip casting method. Specific tests were performed to evaluate the biological properties of the bioceramic samples. In this aim microbial load tests (sanitation/sterility) and cytotoxicity assays on cell cultures-agar diffusion tests performed on L929 cells, and respectively the, MTS viability tests performed on 2 types of cells (L929 and MG-63). The results obtained after the tests showed the biocompatible character of implants, the sterile environments from microbiological point of view and also the absence of pathogenic biological agents.

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Author information

Authors and Affiliations

  1. National Institute of Research and Development for Electrical Engineering, INCDIE ICPE-CA, Bucharest, Romania

    D. Talpeanu, Ch. Tardei, F. Grigore, M. Lucaci, G. Velciu & A. Dumitru

  2. National Institutte for C&D in Physics an Nuclear Engineering, IFIN–HH, Magurele, Ilfov, Romania

    D. Savu

Authors
  1. D. Talpeanu
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  2. Ch. Tardei
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  3. F. Grigore
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  4. M. Lucaci
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  5. G. Velciu
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  6. A. Dumitru
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  7. D. Savu
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Editor information

Editors and Affiliations

  1. Department Microelectronics and Biomedical Engineering, Technical University of Moldova, Chisinau, Moldova

    Victor Sontea

  2. Academy of Sciences of Moldova, Chisinau, Moldova

    Ion Tiginyanu

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© 2016 Springer Science+Business Media Singapore

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Cite this paper

Talpeanu, D. et al. (2016). Biological Evaluation of Slip Casting Hydroxyapatite Intended for Cranioplasty. In: Sontea, V., Tiginyanu, I. (eds) 3rd International Conference on Nanotechnologies and Biomedical Engineering. IFMBE Proceedings, vol 55. Springer, Singapore. https://doi.org/10.1007/978-981-287-736-9_76

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  • DOI: https://doi.org/10.1007/978-981-287-736-9_76

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-287-735-2

  • Online ISBN: 978-981-287-736-9

  • eBook Packages: EngineeringEngineering (R0)

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