Abstract
Inula racemosa Hook. f. (Asteraceae) is a stout herbaceous perennial plant (up to 1.75 m tall) with basal leaves arranged in a racemose manner. It is used in Indian Ayurvedic medicine, Chinese Traditional Medicine (CTM), Bhutanese Sowa Rigpa Medicine (BSM), and European homeopathy for treating various disorders including cough, dyspnoea, asthma, tuberculosis, pain, acute enteritis, dysentery, angina, hyperlipidaemia, hepatic ischaemia and ischaemic heart diseases. The phytochemical studies of I. racemosa extract resulted in the isolation of 67 compounds, and most of them belong to the chemical class of terpenoids. The pharmacological studies of its crude extracts and compounds demonstrated analgesic, anti-inflammatory, antimicrobial, antiparasitic, anticancer, antiasthmatic, antiallergic, antidiabetic, antiapoptotic, cardioprotective, and hepatoprotective properties. The isolated compounds possessed anticancer, antiproliferative, and antiplatelet activities. This chapter discusses the distribution, taxonomy, ethnobotany, pharmacognosy, phytochemistry, pharmacology, and the trade and industry of Inula racemosa.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Aberer W (2008) Contact allergy and medicinal herbs. J Dtsch Dermatol Ges 6(1):15–24. https://doi.org/10.1111/j.1610-0387.2007.06425.x
Aimil pharmaceutical (2021) Best medicine for jaundice, ayurvedic treatment for jaundice and hepatitis. https://www.aimilpharmaceuticals.com/product/amlycure/. Accessed 20 Nov 2021
Ajani H, Patel HP, Shah G, Acharya SR, Shah SK (2009) Evaluation of antidiabetic effect of methanolic extract of Inula racemosa root in Rats. Pharmacologyonline 3:118–129
Alam P, Tyagi R, Farah MA, Rehman MT, Hussain A, Aljmi MF, Siddiqui NA, Al-Anazi KM, Amin S, Mohd M, Mir SR (2021) Cytotoxicity and molecular docking analysis of racemolactone I, a new sesquiterpene lactone isolated from Inula racemosa. Pharm Biol 59(1):943–954. https://doi.org/10.1080/13880209.2021.1946090
Anonymous (1990) Thai herbal pharmacopoeia. Ministry of Public Health, Department of Medical Sciences, Nonthaburi
Anonymous (2000) Thai herbal pharmacopoeia. Ministry of Public Health, Department of Medical Sciences, Nonthaburi
Anonymous (2004) The Ayurvedic Pharmacopoeia. Ministry of Health and Family Welfare Department of Ayush, India
Arora RK, Maheshwari ML, Chandel KPS, Gupta R (1980) Mano (Inula racemosa): little known aromatic plant of Lahaul valley, India. Econ Bot 34:175–180. https://doi.org/10.1007/BF02858632
Arumugam P, Murugan M (2013) Antimutagenic and antiapoptotic effects of aqueous root extract of Inula racemosa Hook. f. on 4-NQO-induced genetic damage in mice. ISRN Pharmacol 2013:1–5. https://doi.org/10.1155/2013/768359
Ayursun Pharma (2021) Herbal tablet for neuro muscular communication-epilac tablet. http://www.ayursun.in/herbal-tablet-for-neuro-muscular-communication-epilac-tablet-4089011.html. Accessed 1 Nov 2021
Baidyanath Research Foundation (2021) Baidyanath Ayurvedant Cardiwin DS tablet. https://www.healthmug.com/product/baidyanath-ayurvedant-cardiwin-ds-tablet-60tab/1707925553. Accessed 10 Nov 2021
Banerjee G, Singh NB (2016) Anti-diabetic composition. Patent No.–US 2016/0193269 A1
Banerjee G, Dias PM, Kalathil R (2014) Plant extract of inula racemosa. Patent No.–WO 2014/124803 A1
Banerjee G, Kadamkode V, Kalathil R, Majumder S (2015) Composition comprising theanine and an extract of Inula Racemosa. Patent No.–US 2015/0356164 A1
Bano H, JIA B, Lone FA, Noor F, Bhat MA, Nazir N (2019) Effect of phytohormones and other dormancy breaking chemicals on seed germination of Inula racemosa Hook. f. A critically endangered medicinal plant of North-Western Himalaya. Int J Curr Microbiol App Sci 8(03):866–876. https://doi.org/10.20546/ijcmas.2019.803.104
Barstow S (2021) Images and observations of mostly edible plants in Norway. https://doi.org/10.5281/zendo.4576563. Accessed 28 Sept 2021
Bhūtyā RK (2011) Ayurvedic medicinal plants of India, Vol I. Scientific Publishers, Jodhpur, p 248
Bioayurveda (2021) Pushkarmool tablet for respiratory strength and allergy relief. https://www.bioayurveda.in/products/pushkarmool-tablet. Accessed 9 Nov 2021
Bokadia MM, Macleod AJ, Mehta SC, Mehta BK, Patel H (1986) The essential oil of Inula racemosa. Phytochemistry 25(12):2887–2888
Chabukswar AR, Kuchekar BS, Jagdale SC, Lokhande PD, Raut CG (2010) Cardio-protective activity of Inula racemosa. Int J Chem Sci 8(3):1454–1552
Chakrapani Ayurveda (2021) Chakrapani ayurveda clinic research centre (Pushkarmool capsule). https://www.chakrapaniayurveda.com/shop/products/capsules/ pushkarmool-capsule/. Accessed 5 Oct 2021
Chaturvedi P, Shukla S, Tripathi P, Chaurasia S, Singh SK, Tripathi YB (1995) Comparative study of Inula racemosa and Saussurea lappa on the glucose level in Albino rats. Anc Sci Life 15(1):62–70
Choudhary G (2012) Mast cell stabilizing activity of Inula racemosa. Int J Adv Pharm Biol Chem 1(4):465–468
Dabur India limited (2021) Khadiradi gutika. https://www.dabur.com/in/en-us/ayurvedic-herbal-products/dabur-khadiradi-gutika. Accessed 7 sept 2021
Das A (2008) Agro-techniques of selected medicinal plants. The Energy and Resources Institute, New Delhi, pp 139–143
de Vries H, Lemmens M (2021). Nature data from around the world. https://doi.org/10.15468/5nilie. Accessed 12 Oct 2021
Dorji K, Tobgay S, Yangdon N (2017) The Ethnobotanical studies of medicinal and aromatic plants in Sakteng Wildlife Sanctuary, Trashigang, Bhutan. Int J Curr Res Biosci Plant Biol 4(4):75–82. https://doi.org/10.20546/ijcrbp.2017.404.011
Doshi M, Vasavada S, Joshi M, Mody S (2003) Herbal cough formulations and process for the preparation thereof. Patent No US 2003/ 0228383 A1
Dubey GP, Rajamanickman GV (2016) Ayurvedic formulation for treating coronary heart disease. Patent No–EP 2393503 B1
Dwivedi S, Somani PN, Udupa KN (1989) Role of Inula racemosa and Saussurea lappa in management of angina pectoris. Int J Crude Drug Res 27(4):217–222. https://doi.org/10.3109/13880208909116904
Firdous Q, Bhat MF, Hussain MM (2018) Ethnopharmacology, phytochemistry and biological activity of Inula racemosa Hook. f: a review. Int J Res Ayurveda Pharm 9(1):95–102. https://doi.org/10.7897/2277-4343.09120
Gholap S, Kar A (2003) Effects of Inula racemosa root and Gymnema sylvestre leaf extracts in the regulation of corticosteroid-induced diabetes mellitus: involvement of thyroid hormones. Pharmazie 58(6):413–415
Gholap S, Kar A (2004) Hypoglycaemic effects of some plant extracts are possibly mediated through inhibition in corticosteroid concentration. Pharmazie 59(11):876–878
Gnanasekaran D, Umamaheswara RC, Jaiprakash B, Narayanan N, Ravi KY, Hannah E (2012) In vitro hepatoprotective activity of Inula racemose (roots) against CCl4 induced toxicity. Int J Res Rev Pharm Appl Sci 2(3):578–587
Goraya GS, Ved D (2017) Medicinal plants in India: an assessment of their demand and supply. National Medicinal Plants Board, Indian Council of Forestry Research and Education, Dehradun
Goyal R, Chhabra BR, Kalsi PS (1990) Three oxygenated alantolides from Inula racemosa. Phytochemistry 29(7):2341–2343. https://doi.org/10.1016/0031-9422(90)83069-D
Greiber T, Moreno SP, Åhrén M, Carrasco JN, Kamau EC, Medaglia JC, Julia OM, Welch FP, Ali N, Williams C (2012) An explanatory guide to the nagoya protocol on access and benefit-sharing. IUCN in collaboration with the IUCN Environmental Law Centre, Bonn, Germany, Gland, Switzerland
Grimaud F (2009) Les Astéracées du Ladakh dans la médecine tibétaine. Phytothérapie 7(5):255–261. https://doi.org/10.1007/s10298-009-0406-7
He Q, Liu XC, Sun RQ, Deng ZW, Du SS, Liu ZL (2014) Mosquito larvicidal constituents from the ethanol extract of Inula racemosa Hook. f. roots against Aedes albopictus. J Chem 2014:1–6. https://doi.org/10.1155/2014/738796
Heilen Biopharm (2021) Pushkarmool herbal powder (Inula Racemosa). https://heilenbiopharm.shop/products/pushkarmool-herbal-powder-inula-racemosa-kashmira-poushkara-puskara-mula-sugandhikam?_pos=1&_sid=77c37a89b&_ss=r&variant. Accessed 10 Nov 2021
Herbs Forever (2021) Traditional authentic ayurvedic herbal powder (Pushkarmool powder). https://herbsforever.com/product/pushkarmool-powder/. Accessed 5 Nov 2021
Jabeen N, Shawl AS, Dar GH, Jan A, Sultan P (2007) Micropropagation of Inula racemosa Hook. f. A valuable medicinal plant. Int J Bot 3(3):296–301. https://doi.org/10.3923/ijb.2007.296.301
Jamna J, Balakrishnan R, Ramakrishnan P, Sarala S, Jolly CI (2012) Comparative pharmacognostic study of Inula racemosa Hook. f. and its adulterant Coffea travancorensis Wight & Arn. Indian J Nat Prod Resour 3(3):386–394
Jamtsho T, Yeshi K, Wangchuk P (2021) Comparative analysis of two Himalayan Aconitum species for their phytopharmaceutical properties. J Herb Med. https://doi.org/10.1016/j.hermed.2021.100497
Kalachaveedu M (2015) Hepatoprotective activity of isoalantolactone isolated from the roots of Inula racemosa (Hook. F). Indian J Net Prod 29(1):29–56
Kalsi PS, Goyal R, Talwar KK, Chhabra BR (1988) Epoxy alantolides: isoinunal, a new potent plant growth regulator from Inula racemosa. Phytochemistry 27(7):2079–2081. https://doi.org/10.1016/0031-9422(88)80100-6
Kapoor S (2018) Inula racemosa: an insight into callus induction, secondary metabolites, and its therapeutic potential. J Pharm Innov 7(6):27–32
Kaur B, Kalsi PS (1985) Stereostructures of inunal and isoalloalantolactone, two biological active sesquiterpene lactones from Inula racemosa. Phytochemistry 24(9):2007–2010
Kaur R, Kashyap A, Majeed S, Chauhan NS, Bhardwaj SB (2010) In vitro propagation and conservation of Inula racemosa Hook. f. an endangered medicinal plant of temperate origin. J Adv Lab Res Biol 1(1):67–70
Khan A, Shah RD, Pallewar S (2010) Evaluation of anti-inflammatory and analgesic activity of ethanolic extracts of Inula racemosa and Albizia amara. Int J Pharmacogn Phytochem Res 3(2):22–27
Khan M, Mir SR, Ali A, Yusuf M, Ali M (2014) Aliphatic and eudesmanolide esters extracted from the roots of Inula racemosa Hook. Pharmacogn Mag 10(37):40–46. https://doi.org/10.4103/0973-1296.126657
Khare CP (2007) Indian medicinal plants: an illustrated dictionary. Springer, New York, p 329
Khurana P, Singh DA, Saroch DV (2015) Role of Pushkarmool in the asthma management: a conceptual study. J Tradt Nat Med 1(1):10–12
Kimothi GP (2014) Pushkarmool (Inula racemosa Hook. f.): a drug with potential bronchodilatory properties. Info Ayurveda 10:20–22
Kumar SA (2014) Medicinal values of Inula racemosa Hook.f. (Pushkarmool). Unique J Ayurvedic Herb Med 2(2):11–13
Lal B, Singh KN (2008) Indigenous herbal remedies used to cure skin disorders by the natives of Lahaul-Spiti in Himachal Pradesh. Indian J Tradit Knowl 7(2):237–241
Liu CH, Mishra AK, Tan RX (2006) Repellent, insecticidal and phytotoxic activities of isoalantolactone from Inula racemosa. Crop Prot 25(5):508–511. https://doi.org/10.1016/j.cropro.2005.05.008
Lokhande PD, Gawai KR, Kodam KM, Kuchekar BS, Chabukswar AR, Jagdale SC (2007) Antibacterial activity of isolated constituents and extract of root of Inula racemosa. Res J Med Plant 1(1):7–12
Ma S, Hu F, Yang Y, Wang W, Zhang D, Chang X (2010) Inula racemosa medicinal material and artificial culture method of sprout root thereof. Patent No. CN 101647359 A
Ma YY, Zhao DG, Gao K (2012) Structural investigation and biological activity of sesquiterpene lactones from the traditional Chinese herb Inula racemosa. J Nat Prod 76(4):564–570. https://doi.org/10.1021/np300742d
Ma YY, Zhao DG, Zhai Y, Li Y, Gao K (2013) Trinorsesquiterpenoids from Inula racemosa. Phytochem Lett 6(4):645–648. https://doi.org/10.1016/j.phytol.2013.08.004
Mangathayaru K (2009) Pharmacognostic studies of Inula racemosa Hook. f and Erythrina variegata linn on experimental atherosclerosis. Doctor of Philosophy Thesis, Sri Ramachandra Medical College and Research Institute, Porur, Chennai, India
Manipuri P, Indala R, Jagaralmudi A, Kumar RK (2013) Hepatoprotective effect of Inula racemosa on hepatic ischemia/reperfusion induced injury in rats. J Bioanal Biomed 5(2):22–27. https://doi.org/10.4172/1948-593X.1000076
Marc EB, Nelly A, Annick DD, Frederic D (2008) Plants used as remedies antirheumatic and antineuralgic in the traditional medicine of Lebanon. J Ethnopharmacol 120(3):315–334. https://doi.org/10.1016/j.jep.2008.08.024
Marisetti AK (2018) Review on phytochemical and phyto therapeutic properties of Inula racemosa. J Appl Sci 4(12):1–7
Mishra A, Thakur M, Alok S (2016) Evaluation of immunomodulatory activity of polysaccharide fraction of Inula racemosa, Bombax ceiba and Allium sativum. Int J Pharm Sci Res 7(9):3749–3755. https://doi.org/10.13040/IJPSR.0975-8232
Modi SSB, Doshi MM, Joshi MD (2000) Anticoughing preparation and method of its preparing. Patent No–RU 2157226 C2
Moerman DE (1986) Medicinal plants of native America, technical reports, vol II. University of Michigan Museum of Anthropology, Ann Arbor, p 910
Mohan S, Gupta D (2017) Phytochemical analysis and differential in vitro cytotoxicity assessment of root extracts of Inula racemosa. Biomed Pharmacother 89:781–795. https://doi.org/10.1016/j.biopha.2017.02.053
Molur S, Walker S (1998) Report of the workshop “Conservation assessment and management plan for selected medicinal plant species of northern, north eastern and central India” (BCPP-Endangered Species Project). Zoo Outreach Organisation, Conservation Breeding Specialist Group, Coimbatore, India, p 62
Nengroo RZ, Rauf A (2020) Inula racemosa and Digitalis purpurea from Kashmir: fatty acid composition, antioxidant, antibacterial activities, and functional group evaluation. Flavour Fragr J 35(6):653–665. https://doi.org/10.1002/ffj.3604
Ojha S, Nandave M, Kumaria S, Arya DS (2010) Cardio protection by Inula racemosa Hook in an experimental model of myocardial ischemic reperfusion injury. Indian J Exp Biol 48(9):918–924
Ojha S, Bharti S, Sharma AK, Rani N, Bhatia J, Kumari S, Arya DS (2011) Effect of Inula racemosa root extract on cardiac function and oxidative stress against isoproterenol-induced myocardial infarction. Indian J Biochem Biophys 48(1):22–28
Organic India (2021) Organic India: breathe free 60 capsules–respiratory & congestion relief. https://www.organicindia.com/shop/herbal-formulations/breathe-free-60-capsules-bottle.html. Accessed 6 Nov 2021
Pal HC, Sehar I, Bhushan S, Gupta BD, Saxena AK (2010) Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce apoptosis in leukemia HL-60 cells by Inula racemosa. Toxicol in Vitro 24(6):1599–1609. https://doi.org/10.1016/j.tiv.2010.06.007
Patanjali Ayurved limited (2021) Divya mukta vati extra power. https://www.patanjaliayurved.net/product/ayurvedic-medicine/vati/divya-mukta- vati-extra-power/125. Accessed 2 Nov 2021
Paulsen E (2002) Contact sensitization from compositae-containing herbal remedies and cosmetics: compositae-based remedies and cosmetics. Contact Dermatitis 47(4):189–198. https://doi.org/10.1034/j.1600-0536.2002.470401.x
Planet Ayurveda (2020) Pushkarmool powder. In: Planet ayurveda, holistic healing through herbs. https://global.planetayurveda.com/products/pushkarmool-powder?variant=23446572826688. Accessed 2 Nov 2021
Prajapati ND (ed) (2003) A handbook of medicinal plants: a complete sourcebook. Agrobios, Jodhpur, p 712
Rathore S, Raj Y, Debnath P, Kumar M, Kumar R (2022) Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f.–a critically endangered medicinal plant of the western Himalaya. J Ethnopharmacol 283:114613. https://doi.org/10.1016/j.jep.2021.114613
Reich E, Schibli A (2006) High-performance thin-layer chromatography for the analysis of medicinal plants. Thieme, Teningen
Rinchen T, Patel MK, Dolkar P (2019) Agro-technique of critically endangered and commercially viable medicinal plant Inula racemosa Hook.f. in cold desert region of Ladakh, India. J Med Plants Stud 7(4):47–50
Sastry JLN, Nesari TM (2018) Dravyaguna Vijnana, Varanasi. Edition, Vol II. Chaukhambha Orientalia, Bangalore, Karnataka, p 241
Schippmann U, Leaman DJ, Cunningham AB (2002) Impact of cultivation and gathering of medicinal plants on biodiversity: global trends and issues. FAO, Rome, pp 1–21
Seca AML, Grigore A, Pinto DCGA, Silva AMS (2014) The genus Inula and their metabolites: from ethnopharmacological to medicinal uses. J Ethnopharmacol 154(2):286–310. https://doi.org/10.1016/j.jep.2014.04.010
Shaanxi Iknow Biotechnology Co., Ltd. (2021) Herbal extract Inula racemosa extract with high quality. https://iknowbio.en.made-inchina.com/product/xBJEqIAvTlRn /China-Herbal-Extract-Inula-Racemosa-Extract-with-High-Quality.html. Accessed 9 Nov 2021
Shabir PA, Nawchoo IA, Wani AA (2013) Among and within-population variation in growth dynamics and floral sex ratios in Inula racemosa; a critically endangered medicinal herb of North West Himalayas. Int J Biodivers Conserv 5(12):796–802. https://doi.org/10.5897/IJBC2013.0621
Shah M, Coulson S (2021) Artportalen (Swedish species observation system). Version 92.261. SLU Artdatabanken. https://doi.org/10.15468/kllkyl. Accessed 28 Sept 2021
Shah WA, Dar MY, Qurishi MA (2009) New epoxyalantolactone from Inula racemosa. J Res Educ Indian Med 15(1):11–14
Sharma P, Malav A (2017) A review on the micropropagations of an important medicinal plant Inula racemosa Hook. f. Int J Dev Res 07(10):16369–16372
Sharma V, Hem K, Sharma D, Singh VP, Singh NK (2016) Ethnopharmacology, phytochemistry and pharmacology of Inula racemosa Hook.f. J Nat Prod Resour 2(1):40–46
Shetty MV (2020) Herbo-mineral formulation for prevention, treatment, and management of diabetes and method of preparation thereof. Patent No–US 2018/0236018 A1
Shirole TS, Jagtap AG, Phadke AS, Velhankar RD (2013) Preventive effect of ethanolic extract of “Inula racemosa” on electrocardiographic, biochemical and histopathological alteration in isoproterenol induced myocardial infarction in rats. Int J Res Phytochem Pharmacol 3:13–22
Shishodia S, Harikumar KB, Dass S, Ramawat KG, Aggarwal BB (2008) The guggul for chronic diseases: ancient medicine, modern targets. Anticancer Res 28:3647–3664
Singh N, Nath R, Gupta ML, Kohli RP (1980) An experimental evaluation of anti-asthmatic potentialities of Inula racemosa (Puskar Mul). Quart J Crude Drug Res 18(2):89–96. https://doi.org/10.3109/13880208009065184
Singh TN, Upadhyay BN, Tewari CM, Tripathi SN (1985) Management of diabetes mellitus (prameha) with Inula racemosa and Cinnamomum tamala. Anc Sci Life 5(1):9–16. PMID: 22557492; PMCID: PMC3331436
Singh RP, Singh R, Ram P, Batliwala PG (1993) Use of pushkar-guggul, an indigenous anti-ischemic combination, in the management of ischemic heart disease. Int J Pharmacogn 31(2):147–160. https://doi.org/10.3109/13880209309082932
Singh, NB, Banerjee, G, Blom, WAM, Gouka, RJ, Kalathil, R, Majumder, S (2015) Edible composition comprising an extract of Inula racemose and naringin. Patent No.–US 2015/0343.007 A1
Soni DMK, Sharma DO (2018) Pushmarmoola (Inula racemosa Hook.f.): ayurvedic review. World J Pharm Med Res 4(3):199–201
Srivastava S, Gupta PP, Prasad R, Dixit KS, Palit G, Ali B, Misra G, Saxena RC (1999) Evaluation of antiallergic activity (type I hypersensitivity) of Inula racemosa in rats. Indian J Physiol Pharmacol 43(2):235–241
Svirin S, Pospelov I, Panasenko N, Seregin AP, Shilnikov D, Golyakov P, Nesterova S, Kosachev P, Chimitov D, Suslova E, Ebel AL, Gamova N, Dudov S, Pyak A (2021). Flora of Russia. Version 1.4. Lomonosov Moscow State University, Moskva. https://doi.org/10.15468/956zqa. Accessed 7 Nov 2021
Swinnen K et al (2018) Waarnemingen. be–Non-native plant and animal occurrences in Flanders and the Brussels capital region, Belgium. Bioinvasions Rec 7(3):335–342. https://doi.org/10.3391/bir.2018.7.3.17
Tan RX, Tang HQ, Hu J, Shuai B (1998) Lignans and sesquiterpene lactones from Artemisia Sieversiana and Inula racemosa. Phytochemistry 49(1):157–161. https://doi.org/10.1016/S0031-9422(97)00889-3
Tansukh Herbals (2021) Pushkarmool churna. Tansukh herbals private limited. https://www.tansukhherbals.com/products/pushkarmool-churna. Accessed 5 Nov 2021
Tenzin S, Tashi S (2015) Monograph on traditional medicine of Bhutan. Menjong Sorig Pharmaceuticals, Department of Traditional Medicine Services, Ministry of Health, Thimphu
Tripathi YB, Chaturvedi P (1995) Assessment of endocrine response of Inula racemosa in relation to glucose homeostasis in rats. Indian J Exp Biol 33(9):686–689
Tripathi YB, Tripathi P, Upadhyay BN (1988) Assessment of the adrenergic beta-blocking activity of Inula racemosa. J Ethnopharmacol 23(1):3–9. https://doi.org/10.1016/0378-8741(88)90109-2
Tyagi R, Alam P, Rehman MT, AlAjmi MF, Hussain A, Amin S, Mujeeb M, Mir SR (2021) A new cytotoxic dimeric sesquiterpene isolated from Inula racemosa Hook. f. (Root): in vitro and in silico analyses. Separations 8(1):2–14. https://doi.org/10.3390/separations8010002
Ueda, K. (2020) iNaturalist research-grade observations. https://doi.org/10.15468/ab3s5x. Accessed 1 Nov 2021
Vadnere GP, Gaud RS, Singhai AK, Somani RS (2009) Effect of Inula racemosa root extract on various aspects of Asthma. Pharmacologyonline 2:84–94
Vanreusel W, Barendse R, Steeman R, Gielen K, Swinnen K, Desmet P, Herremans M (2021) Waarnemingen.be–non-native plant occurrences in Flanders and the Brussels capital region, Belgium. Version 1.34. Natuurpunt. https://doi.org/10.15468/smdvdo. Accessed 5 Nov 2021
Ventura MT, Viola M, Calogiuri G, Gaeta F, Pesole O, Romano A (2006) Hypersensitivity reactions to complementary and alternative medicine products. Curr Pharm Des 12:3393–3399. https://doi.org/10.2174/138161206778194079
Walter KS, Gillett HJ (eds) (1998) 1997 IUCN red list of threatened plants. IUCN, World Conservation Union, Cambridge
Wang Z, Geng L, Chen Z, Lin B, Zhang M, Zheng S (2017) In vivo therapeutic potential of Inula racemosa in hepatic ischemia-reperfusion injury following orthotopic liver transplantation in male albino rats. AMB Express 7(1):211. https://doi.org/10.1186/s13568-017-0511-1
Wangchuk P (2009) Monographs on medicinal plants of Bhutan, vol II. Pharmaceutical and Research Unit, Ministry of Health, Thimphu
Wangchuk P (2014) Phytochemical analysis, bioassays and the identification of drug lead compounds from seven Bhutanese medicinal plants. Doctor of Philosophy Thesis. Department of Chemistry, University of Wollongong, New South Wales, Australia
Wangchuk P, Yeshi K, Vennos C, Mandal SC, Kloos S, Nugraha AS (2020) Three medicinal Corydalis species of the Himalayas: their ethnobotany, pharmacognosy, phytochemistry and pharmacology. J Herb Med 23:100384. https://doi.org/10.1016/j.hermed.2020.100384
Wani AP, Ganaie KA, Nawchoo IA, Wafai BA (2006) Phenological episodes and reproductive strategies of Inula racemosa (Asteraceae), a critically endangered medicinal herb of North West Himalaya. Int J Bot 2(4):388–394. https://doi.org/10.3923/ijb.2006.388.394
Wani IA, Kumar V, Verma S, Tasleem Jan A, Rather IA (2020) Dactylorhiza hatagirea (D. Don) Soo: a critically endangered perennial orchid from the north-west Himalayas. Plan Theory 9(12):1644. https://doi.org/10.3390/plants9121644
WHO (2021) Quality control methods for herbal materials. Updated edition of Quality control methods for medicinal plant materials, 1998. World Health Organisation, Geneva
Xu LW, Shi YP (2011) Sesquiterpenoids from Inula racemosa. J Asian Nat Prod Res 13(06):570–574. https://doi.org/10.1080/10286020.2011.575066
Yang YQ, Ma HL, Zhang ZX (2009) Study on medicinal constituents of cultivated Inula racemosa. Master Thesis, Henan University of Science and Technology, China
Yashwant S (2011) Inula racemosa Hook. f: a potential medicinal crop in the cold desert agro-ecosystem of North Western Himalaya, India. J Med Plant Res 5(26):6218–6223. https://doi.org/10.5897/JMPR11.1040
Yousheng C, Anderberg AA (2011) Inuleae. In Flora of China Vol. 20–21 (Asteraceae). Science press and Missouri Botanical Garden Press, Beijing and St. Louis, p 820–850
Zhang T, Xiao W, Gong T, Yang Y, Chen RY, Yu DQ (2010) Two new eudesmanolides from Inula racemosa. J Asian Nat Prod Res 12(9):788–792. https://doi.org/10.1080/10286020.2010.504662
Zhang SD, Qin JJ, Jin HZ, Yin YH, Li HL, Yang XW, Li X, Shan L, Zhang WD (2012a) Sesquiterpenoids from Inula racemosa Hook.f. inhibits nitric oxide production. Planta Med 78(02):166–171. https://doi.org/10.1055/s-0031-1280294
Zhang T, Gong T, Yang Y, Chen RY, Yu DQ (2012b) Two new eudesmanolides from Inula racemosa and their bioactivities. Phytochem Lett 5(2):229–232. https://doi.org/10.1016/j.phytol.2011.12.014
Zhang, W, Su J, Shan L, Li H, Shen Y, Ye J, Chen B, Lin S (2013) Preparation method of Inula racemosa sesquiterpene lactone. Patent No.–CN 103251666 A
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Wangchuk, P., Jamtsho, T. (2023). Inula racemosa Hook. f. Pushkarmool: Its Ethnobotanical Uses, Phytochemicals, and Pharmacological Activities. In: Sharma, A., Nayik, G.A. (eds) Immunity Boosting Medicinal Plants of the Western Himalayas. Springer, Singapore. https://doi.org/10.1007/978-981-19-9501-9_11
Download citation
DOI: https://doi.org/10.1007/978-981-19-9501-9_11
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-19-9500-2
Online ISBN: 978-981-19-9501-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)