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Droplet Microfluidics: A Multiphase System

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Applied Complex Flow

Part of the book series: Emerging Trends in Mechatronics ((emerg. Trends in Mechatronics))

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Abstract

Being able to control and manipulate multiphase flows in microfluidic channels is beneficial in a wide range of high-throughput biological and chemical applications including generating thousands of droplets in which particles and cells encapsulate, each serving as a microreactor. To design and operate such complex systems, a comprehensive understanding of the fundamentals of multiphase flow at confined microchannels is essential. Even though there are some reviews in the literature on droplet generation using a microfluidic channel, there is a distinct lack of CFD-based reviews. This chapter focuses on numerical research in the literature as Computational Fluid Dynamics (CFD) can provide some insight that could be difficult to obtain experimentally. In this chapter, first, the flow physics of droplet generation in microfluidic channels is explained. Different designs, geometries, and droplet generation regimes are mentioned and then the effect of some parameters in Newtonian and non-Newtonian systems are explored. Then, two cases of complex droplet formation are discussed. We hope this chapter can help readers to understand the flow physics involved in microfluidic microdroplet technologies as well as provide insight into CFD approaches in this field.

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Authors and Affiliations

  1. Department of Mechanical, Aerospace and Civil Engineering, The University of Manchester, Manchester, M13 9PL, UK

    Maryam Fatehifar & Alistair Revell

  2. School of Mechanical Engineering, University of Leeds, Leeds, LS2 9JT, UK

    Masoud Jabbari

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  1. Maryam Fatehifar
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  2. Alistair Revell
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  3. Masoud Jabbari
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Correspondence to Masoud Jabbari .

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  1. School of Engineering, Computing and Mathematics, Oxford Brookes University, Oxford, UK

    Aydin Azizi

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Fatehifar, M., Revell, A., Jabbari, M. (2023). Droplet Microfluidics: A Multiphase System. In: Azizi, A. (eds) Applied Complex Flow. Emerging Trends in Mechatronics. Springer, Singapore. https://doi.org/10.1007/978-981-19-7746-6_3

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