Skip to main content

Identification of Sentinel Lymph Nodes in Breast Cancer Surgery

  • Chapter
  • First Online:
Fluorescence-Guided Surgery
  • 147 Accesses

Abstract

The safety and usefulness of sentinel node biopsy have been established as a standard treatment for breast cancer. In Japan, the indocyanine green (ICG) fluorescence method has been developed as an alternative to the dye and radioisotope (RI) methods, which have been used as tracers in many institutions around the world. In this chapter, we outline the actual technique of sentinel lymph node biopsy using ICG fluorescence imaging in breast cancer surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Japanese Breast Cancer Society. Breast cancer treatment guidelines (1) treatment edition 2018. Kinbara Shuppan; 2018. p. 228–42.

    Google Scholar 

  2. Kim T, Guiliano AE, Lyman GH, et al. Lymphatic mapping and sentinel lymph node biopsy in early-stage breast carcinoma: a meta-analysis. Cancer. 2006;106:4–16.

    Article  PubMed  Google Scholar 

  3. Sugie T, Sawada T, Tagaya N, et al. Comparison of indocyanine green fluorescence and blue dye methods in the detection of sentinel lymph nodes in early-stage breast cancer. Ann Surg Oncol. 2013;20:2213–8.

    Article  PubMed  Google Scholar 

  4. Xiong L, Gazyakan E, Yang W, et al. Indcyanine green fluorescence-guided sentinel node biopsy: a meta-analysis on detection rate and diagnostic performance. Eur J Surg Oncol. 2014;40:843–9.

    Article  CAS  PubMed  Google Scholar 

  5. Giuliano AE, Hunt KK, Ballman KV, et al. Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial. JAMA. 2011;305:569–75.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Morton DL, Wen DR, Wong JH, et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg. 1992;127:392–9.

    Article  CAS  PubMed  Google Scholar 

  7. Krag DN, Anderson SJ, Julian TB, et al. Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial. Lancet Oncol. 2010;11:927–33.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Giuliano AE, Kirgan DM, Guenther JM, et al. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg. 1994;220:391–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Kitai T, Kawashima M. Transcutaneous detection and direct approach to the sentinel node using axillary compression technique in ICG fluorescence- navigated sentinel node biopsy for breast cancer. Breast Cancer. 2012;19:343–8.

    Article  PubMed  Google Scholar 

  10. Sugie T, Kinoshita T, Masyda N, et al. Evaluation of the clinical utility of the ICG fluorescence method compared with the radioisotope method for sentinel lymph node biopsy in breast cancer. Ann Surg Oncol. 2016;23:44–50.

    Article  PubMed  Google Scholar 

  11. Sugie T, Ikeda T, Kawaguchi A, et al. Sentinel lymph node biopsy using indocyanine green fluorescence in early-stage breast cancer: a meta-analysis. Int J Clin Oncol. 2017;22:11–7.

    Article  CAS  PubMed  Google Scholar 

  12. Takada M, Takeuchi M, Suzuki E, et al. Real-time navigation system for sentinel lymph node biopsy in breast cancer patients using projection mapping with indocyanine green fluorescence. Breast Cancer. 2018;25:650–5.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tomoharu Sugie .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Tada, M., Sugie, T. (2023). Identification of Sentinel Lymph Nodes in Breast Cancer Surgery. In: Ishizawa, T. (eds) Fluorescence-Guided Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-19-7372-7_20

Download citation

  • DOI: https://doi.org/10.1007/978-981-19-7372-7_20

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-7371-0

  • Online ISBN: 978-981-19-7372-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics