Abstract
Continuous-flow aldol-type reactions are the other essential part of the aldol-hydrogenation strategy (Scheme 4.1). In Chap. 2, flow aldol condensation between nitromethane and aldehyde using amine-functionalized SiO2 catalyst was described. To expand the scope of nucleophiles and to access both aldol compounds and dehydrated compounds selectively, I decided to investigate different types of heterogeneous catalysts.
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Saito, Y. (2023). Anion Exchange Resins as Catalysts for Direct Aldol-Type Reactions of Ketones, Esters, and Nitriles Under Continuous-Flow Conditions. In: Multistep Continuous Flow Synthesis of Fine Chemicals with Heterogeneous Catalysts. Springer Theses. Springer, Singapore. https://doi.org/10.1007/978-981-19-7258-4_4
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