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Pathogenesis of Cochlear Nerve Deficiency

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Cochlear Implantation for Cochlear Nerve Deficiency

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Abstract

The etiology and pathogenesis of cochlear nerve deficiency (CND) are unclear and are generally thought to be related to congenital development and acquired degeneration. Congenital developments include early developmental insult that affects both the hindbrain and cochlear formation and later localized insult that is limited to the cochlear inner hair cells, spiral ganglion, or cochlear nerve itself. Acquired degeneration includes cochlear hair cell loss, and the amount of degeneration may differ considerably between the two ears. Furthermore, congenital cytomegalovirus infection may be associated with CND, but the exact mechanism remains to be further explored.

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Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otolaryngology, Beijing, China

    Lihui Huang, Cheng Wen, Jinge Xie, Yiding Yu & Yue Li

  2. Key Laboratory of Otolaryngology-Head and Neck Surgery (Capital Medical University), Ministry of Education, Beijing, China

    Lihui Huang, Cheng Wen, Jinge Xie, Yiding Yu & Yue Li

Authors
  1. Lihui Huang
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  2. Cheng Wen
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  3. Jinge Xie
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  4. Yiding Yu
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  5. Yue Li
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Correspondence to Lihui Huang .

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Editors and Affiliations

  1. Capital Medical University, Beijing Tongren Hospital, Beijing, China

    Yongxin Li

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Huang, L., Wen, C., Xie, J., Yu, Y., Li, Y. (2022). Pathogenesis of Cochlear Nerve Deficiency. In: Li, Y. (eds) Cochlear Implantation for Cochlear Nerve Deficiency. Springer, Singapore. https://doi.org/10.1007/978-981-19-5892-2_2

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  • DOI: https://doi.org/10.1007/978-981-19-5892-2_2

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-5891-5

  • Online ISBN: 978-981-19-5892-2

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