Skip to main content
SpringerLink
Log in

Progress on Schistosomiasis Research in China

  • Chapter
  • First Online:
Tropical Diseases in China

Part of the book series: Public Health in China ((PUBHECH,volume 5))

  • 110 Accesses

Abstract

Schistosomiasis japonica is one of the most important parasitic diseases in China despite a documented history of more than 2100 years. The study and use of diagnostic techniques play an important role in targeting chemotherapy, assessing morbidity, and evaluating control strategies that have been continuously applied in the national schistosomiasis control programme for more than 60 years. The current widely used diagnostic approaches include two types, [1, 2] one is the parasitological techniques (detection of parasite eggs or miracidia in feces), and the other one is immunologic methods (detection of specific antibodies or circulating antigens). In addition, two approaches of molecular biotechnology, such as loop-mediated isothermal amplification (LAMP) and polymerase chain reaction (PCR), both of which are based on amplification of DNA fragments have been developed and successfully transferred from the laboratory to the field [3–5].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bergquist R, Johansen MV, Utzinger J. Diagnostic dilemmas in helminthology: what tools to use and when? Trends Parasitol. 2009;25:151–6.

    Article  PubMed  Google Scholar 

  2. Wu GL. A historical perspective on the immunodiagnosis of schistosomiasis in China. Acta Trop. 2002;82:193–8.

    Article  PubMed  Google Scholar 

  3. Xia CM, Rong R, Lu ZX, et al. Schistosoma japonicum: a PCR assay for the early detection and evaluation of treatment in a rabbit model. Exp Parasitol. 2009;121(2):175–9.

    Article  CAS  PubMed  Google Scholar 

  4. Xu J, Guan ZX, Zhao B, et al. DNA detection of Schistosoma japonicum: diagnostic validity of a LAMP assay for low-intensity infection and effects of chemotherapy in humans. PLoS Negl Trop Dis. 2015;9:e0003668.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Xu J, Rong R, Zhang HQ, et al. Sensitive and rapid detection of Schistosoma japonicum DNA by loop-mediated isothermal amplification (LAMP). Int J Parasitol. 2010;40:327–31.

    Article  CAS  PubMed  Google Scholar 

  6. Kato T, Miura M. On the comparison of some stool examination methods. Jpn J Parasitol. 1954;3:35.

    Google Scholar 

  7. Katz N, Chaves A, Pellegrino J. A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo. 1972;1972(14):397–400.

    Google Scholar 

  8. Qiu LZ, Xue HC. Experimental diagnosis. In: MAO, S. P., editor. Schistosome biology and control of schistosomiasis. Beijing: Publishing House for People’s Health; 1990.

    Google Scholar 

  9. Zhu HQ, Xu J, Zhu R, et al. The establishment and use of creteria to gauge proficiency at detecting common helminth eggs. J Pathogen Biol. 2013a;8:141–3,154. (in Chinese)

    Google Scholar 

  10. Xu J, Chen NG, Feng T, et al. Effectiveness of routinely used assays for the diagnosis of S. japonicum in the field. Chin J Parasitol Parasit Dis. 2007;25:175–9. (in Chinese)

    Google Scholar 

  11. Li L. Value of ultrasound in diagnosis of liver disease for schistosomiasis in different stages. Proceed Clin Med. 2015;24:308–10. (in Chinese)

    Google Scholar 

  12. Gan HR. The intradermal test for antigen of Schistosoma japonicum. Chin Med J. 1936;1:387. (in Chinese)

    Google Scholar 

  13. Song H, Liang Y, Dai J, et al. Evaluation on dipstick dye immunoassay for screening chemotherapy targets of schistosomiasis in a lower endemic area. Chin J Schisto Contr. 2003;15:102–3. (in Chinese)

    Google Scholar 

  14. Shi YE, Han JJ, Zhou ZL, et al. Studies on the indirect hemagglutination test for the diagnosis of S. japonicum. Acta Med Wuhan. 1980;1:26–31. (in Chinese)

    Google Scholar 

  15. Chen NG, Lin DD, Xie SY, et al. Diagnostic efficiency of indirect hemagglutination assay kit for antibody detection of S. japonicum. Chin J Schisto Contr. 2011a;23:377–80. (in Chinese)

    Google Scholar 

  16. Yan ZZ, Lv ZY. The preliminary research and application on the immune enzyme marker technology. Chin Med J. 1978;88:470–3. (in Chinese)

    Google Scholar 

  17. Xu X, Zhang Y, Lin D, et al. Serodiagnosis of Schistosoma japonicum infection: genome-wide identification of a protein marker, and assessment of its diagnostic validity in a field study in China. Lancet Infect Dis. 2014;14:489–97.

    Article  CAS  PubMed  Google Scholar 

  18. Yan ZZ, Wan W, Lu Z, et al. Detection of circulating antigen in schistosomiasis by dot-ELISA with monoclonal antibody. Chin J Parasitol Parasitic Dis. 1990;8:161–4. (in Chinese)

    CAS  Google Scholar 

  19. Guan XH, Shi YE. Collaborative study on evaluation of immunodiagnostic assays in S. japonicum by treatment efficacy assessment. Chin Med J, Chin Med J (Engl). 1996;109:659–64.

    CAS  PubMed  Google Scholar 

  20. Ding JZ, Gan XX, Shen HY, et al. Establishment and application of dot immunogold filtration assay for detection of anti-schistosome antibodies. Chin J Parasit Dis Contr. 1998;11:308–10. (in Chinese)

    Google Scholar 

  21. Tang Y, Wang Y, Shi XH, et al. Rapid detection of specific IgM against Schistosoma japonicum by dot immune-gold filtration assay. Inter J Epide Infect Dis. 2008;35:316–8. (in Chinese)

    Google Scholar 

  22. He W, Zhu YC, Hua W, et al. Development of a rapid immunodiagnosis assay for schistosomiasis-colloidal dye strip immunoassay. Chin J Schisto Contr. 2000;12:18–20. (in Chinese)

    Google Scholar 

  23. Zhu YC, He W, Liang YS, et al. Development of a rapid, simple dipstick dye immunoassay for schistosomiasis diagnosis. J Immunol Methods. 2002;266:1–5.

    Article  CAS  PubMed  Google Scholar 

  24. Yu LL, Ding JZ, Wen LY, et al. Development of a rapid dipstick with latex immunochromatographic assay (DLIA) for diagnosis of schistosomiasis japonica. Parasit Vectors. 2011;4:157.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. van Dam GJ, De Dood CJ, Lewis M, et al. A robust dry reagent lateral flow assay for diagnosis of active schistosomiasis by detection of Schistosoma circulating anodic antigen. Exp Parasitol. 2013;135:274–82.

    Article  PubMed  PubMed Central  Google Scholar 

  26. van Dam GJ, Xu J, Bergquist R, et al. An ultra-sensitive assay targeting the circulating anodic antigen for the diagnosis of Schistosoma japonicum in a low-endemic area. People’s Republic of China Acta Trop. 2015;141:190–7.

    PubMed  Google Scholar 

  27. Lier T, Johansen MV, Hjelmevoll SO, et al. Real-time PCR for detection of low intensity Schistosoma japonicum infections in a pig model. Acta Trop. 2008;105:74–80.

    Article  CAS  PubMed  Google Scholar 

  28. Fung MS, Xiao N, Wang S, et al. Field evaluation of a PCR test for Schistosoma japonicum egg detection in low-prevalence regions of China. Am J Trop Med Hyg. 2012;87:1053–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Zhou XN, Xu J, Chen HG, et al. Tools to support policy decisions related to treatment strategies and surveillance of S. japonicum towards elimination. PLoS Negl Trop Dis. 2011;5:e1408.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Bergquist R, Yang GJ, Knopp S, et al. Surveillance and response: tools and approaches for the elimination stage of neglected tropical diseases. Acta Trop. 2015;141:229–34.

    Article  PubMed  Google Scholar 

  31. Doenhoff MJ, Chiodini PL, Hamilton JV. Specific and sensitive diagnosis of schistosome infection: can it be done with antibodies? Trends Parasitol. 2004;20:35–9.

    Article  PubMed  Google Scholar 

  32. Chen XY, Wang LY, Cai JM, et al. Schistosomiasis control in China: the impact of a 10-year World Bank loan project (1992-2001). Bull World Health Organ. 2005;2005(83):43–8.

    Google Scholar 

  33. Balen J, Zhao ZY, Williams GM, et al. Prevalence, intensity and associated morbidity of Schistosoma japonicum infection in the Dongting Lake region. China Bull World Health Organ. 2007;85:519–26.

    Article  PubMed  Google Scholar 

  34. Wang LD, Chen HG, Guo JG, et al. A strategy to control transmission of Schistosoma japonicum in China. N Engl J Med. 2009;360:121–8.

    Article  CAS  PubMed  Google Scholar 

  35. Lin DD, Liu JX, Liu YM, et al. Routine Kato-Katz technique underestimates the prevalence of Schistosoma japonicum: a case study in an endemic area of the People’s republic of China. Parasitol Int. 2008;57:281–6.

    Article  PubMed  Google Scholar 

  36. Huang MJ, Chen NG, Wu ZQ, et al. Comparison of effect of stool hatching method and Kato-Katz in the field examination of schistosomiasis. Chin J Schisto Contr. 2007;19:458–9. (in Chinese)

    Google Scholar 

  37. Zhu R, Qin ZQ, Feng T, et al. Assessment of effect and quality control for parasitological tests in national schistosomiasis surveillance sites. Chin J Schisto Contr. 2013b;25:11–5. (in Chinese)

    Google Scholar 

  38. Xu J, Feng T, Guo JG, et al. Comprehensive evaluation of several diagnosis agents of S. japonicum in China. Chin J Schisto Contr. 2005;17:116–9. (in Chinese)

    Google Scholar 

  39. Qin ZQ, Xu J, Feng T, et al. Strategic thinking of the construction of national schistosomiasis laboratory network in China. Chin J Schisto Contr. 2013;25:329–32. (in Chinese)

    Google Scholar 

  40. Chen W, Zhu MD, Yan XL, et al. Quality control assessments of feces examination for schistosomiasis in province-level laboratories of Zhejiang Province. Chin J Schisto Contr. 2011b;23:318–20. (in Chinese)

    Google Scholar 

  41. Feng T, Xu J, Hang DR, et al. Conditions of schistosomiasis laboratories at county level. Chin J Schisto Contr. 2011;23:370–6. (in Chinese)

    Google Scholar 

  42. Zhu HQ, Xu J, Zhu R, et al. Comparison of the miracidium hatching test and modified Kato-Katz method for detecting Schistosoma japonicum in low prevalence areas of China. Southeast Asian J Trop Med Public Health. 2014;45:20–5.

    PubMed  Google Scholar 

  43. Andrews P, Thomas H, Pohlke R, et al. Praziquantel. Med Res Rev. 1983;3:147–200.

    Article  CAS  PubMed  Google Scholar 

  44. Chai JY. Praziquantel treatment in trematode and cestode infections: an update. Infect Chemether. 2013;45(1):32–43.

    Article  CAS  Google Scholar 

  45. Pax R, Bennett JL, Fetterer R. A benzodiazepine derivative and praziquantel: effects on musculature of Schistosoma mansoni and Schistosoma japonicum. Naunyn Schmiedeberg's Arch Pharmacol. 1978;304:309–15.

    Article  CAS  Google Scholar 

  46. Harnett W, Kusel JR. Increased exposure of parasite antigens at the surface of adult male Schistosoma mansoni exposed to praziquantel in vitro. Parasitology. 1986;93:401–5.

    Article  CAS  PubMed  Google Scholar 

  47. Aragon AD, Imani RA, Blackburn VR, et al. Towards an understanding of the mechanism of action of praziquantel. Mol Biochem Parasitol. 2009;164:57–65.

    Article  CAS  PubMed  Google Scholar 

  48. Xiao SH. Development of antischistosomal drugs in China, with particular consideration to praziquantel and the artemisinins. Acta Trop. 2005;96:153–67.

    Article  CAS  PubMed  Google Scholar 

  49. Lima RM, Ferreira MA, Ponte TM, et al. Enantioselective analysis of praziquantel and trans-4-hydroxypraziquantel in human plasma by chiral LC-MS/MS: application to pharmacokinetics. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877:3083–8.

    Article  CAS  PubMed  Google Scholar 

  50. Xiao XH, You JQ, Mei JY, et al. In vitro and in vivo effect of levopraziquantel, dextropraziquantel versus racemic praziquantel on different developmental stages of Schistosoma japonicum. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1998;16:335–441. (in Chinese)

    CAS  PubMed  Google Scholar 

  51. Liu YH, Qian MX, Wang XG, et al. Comparative efficacy of praziquantel and its optic isomers in experimental therapy of schistosomiasis japonica in rabbits. Chin Med J. 1986;99:935–40.

    CAS  PubMed  Google Scholar 

  52. Meister I, Ingram K, Cowan N, et al. Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni. Antimicrob Agents Chemother. 2014;58:5466–72.

    Article  PubMed  PubMed Central  Google Scholar 

  53. Mufamadi MS, Pillay V, Choonara YE, et al. A review on composite liposomal technologies for specialized drug delivery. J Drug Deliv. 2011;2011:1–19.

    Article  Google Scholar 

  54. Mourau SC, Costa PI, Salgado HRN, et al. Improvement of antischistosomal activity of praziquantel by incorporation into phosphatidylcholine-containing lipossomes. Int J Pharmacol. 2005;290:157–62.

    Article  Google Scholar 

  55. Frezza TF, Gremiao MPD, Zanotti-Magalhaes EM, et al. Liposomal-praziquantel: Efficacy against Schistosoma mansoni in a preclinical assay. Acta Trop. 2013;128:70–5.

    Article  CAS  PubMed  Google Scholar 

  56. Zheng XS, Duan CZ, Xiao ZD, et al. Transdermal delivery of praziquantel: effects of solvents on permeation across rabbit skin. Biol Pharm Bull. 2008;31:1045–8.

    Article  CAS  PubMed  Google Scholar 

  57. Li XH, Zhang DZ, Yang Y, et al. Effect of praziquantel transdermal delivery on infection of Schistosoma japonicum of mice. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2012;24:155–9. (in Chinese)

    CAS  PubMed  Google Scholar 

  58. Tang S, Chen L, Guo Z, et al. Pharmacokinetics of a new ivermectin/praziquantel oil suspension after intramuscular administration in pigs. Vet Parasitol. 2012;185:229–35.

    Article  CAS  PubMed  Google Scholar 

  59. Tang S, Chen L, Qian M, et al. Pharmacokinetics of a new ivermectin/praziquantel suspension after intramuscular administration in sheep. Vet Parasitol. 2016;221:54–8.

    Article  CAS  PubMed  Google Scholar 

  60. Yang Y, Wang JM, Yan J, et al. Experiment of praziquantel rectal administration in treatment of schistosomiasis in mice. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2011;23:674–6. (in Chinese)

    PubMed  Google Scholar 

  61. Shen XL, Zhang H. Pharmacokinetics of praziquantel liquid suppository in rabbits. J Guangdong Coll Pharm. 2006;22:25–31. (in Chinese)

    CAS  Google Scholar 

  62. Li G, Qiu J, He G, et al. Phamacokinetics and bioavailability of praziquantel suppository in rabbit. Acta Univ Med Tongji. 1994;23(suppl 2):93–5. (in Chinese)

    Google Scholar 

  63. Andrews P. Praziquantel: mechanisms of anti-schistosomal activity. Pharmacol Ther. 1985;29:129–56.

    Article  CAS  PubMed  Google Scholar 

  64. Hong ST, Lee SH, Lee SJ, et al. Sustained-release praziquantel tablet: pharmacokinetics and the treatment of clonorchiasis in beagle dogs. Parasitol Res. 2003;91:316–20.

    Article  PubMed  Google Scholar 

  65. Choi MH, Chang BC, Lee SJ, et al. Therapeutic evaluation of sustained-releasing praziquantel (SRP) for clonorchiasis: phase 1 and 2 clinical studies. Korean J Parasitol. 2006;44:361–6.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Cao L, Hu GH, Guo JG, et al. Compliance study on mass chemotherapy with praziquantel in schistosomiasis hyper-endemic area of Poyang Lake region for successive 6 years. Parasito Infec Dis. 2003;1:153–5. (in Chinese)

    Google Scholar 

  67. Chen CL, You XJ, Zeng XY, et al. Side-effect induced by praziquantel treatment for schistosomiasis. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2005a;17:323–7. (in Chinese)

    Google Scholar 

  68. Cao CL, Bao ZP, Chen L, et al. Compliance of film-coated praziquantel tablets in schistosomiasis transmission-controlled areas. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2011;23:659–63. (in Chinese)

    PubMed  Google Scholar 

  69. Meyer T, Sekljic H, Fuchs S, et al. Taste, a new incentive to switch to (R)-praziquantel in schistosomiasis treatment. PLoS Negl Trop Dis. 2009;3:e357.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Chen MG. Use of praziquantel for clinical treatment and morbidity control of schistosomiasis japonica in China: a review of 30 years’s experience. Acta Trop. 2005;96:168–76.

    Article  CAS  PubMed  Google Scholar 

  71. Xiao SH, Keiser J, Chen MG, et al. Research and development of antischistosomal drugs in the People’s republic of China: a 60-year review. Adv Parasitol. 2010;73:231–95.

    Article  PubMed  Google Scholar 

  72. Guo JG, Cao CL, Hu GH, et al. The role of passive chemotherapy in schistosomiasis control during maintain and consolidate stage. Chin J Parasit Dis Control. 2003;16:266–8. (in Chinese)

    Google Scholar 

  73. Ross AG, Sleigh AC, Li YS, et al. Schistosomiasis in the People’s republic of China: prospects and challenges for the 21st century. Clin Microbiol Rev. 2001;14:270–95.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  74. Zhu R, Guo JG. Role of chemotherapy with praziquantel in schistosomiasis control. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2009;21:154–7.

    Google Scholar 

  75. Chen MG. Chemotherapy in schistosomiasis control program. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2003;15:401. (in Chinese)

    CAS  Google Scholar 

  76. Cao Z, Huang Y, Wang T. Schistosomiasis japonica control in domestic animals: progress and experiences in China. Front Microbiol. 2017;8:1–5.

    Article  Google Scholar 

  77. Cao MK, Tian ZY, Xiao JW, et al. Effect of synchronous chemotherapy of human and livestock to block schistosomiasis transmission in Changde, Hunan province, P.R.China. Hunan Med. 1989;6:9–10. (in Chinese)

    Google Scholar 

  78. Chen X, Wang L, Cai J, et al. Schistosomiasis control in China: the impact of a 10-year World Bank loan project (1992-2001). Bull World Health Organ. 2005b;83:43–8.

    Google Scholar 

  79. Zhang JF. A detailed chronological record of project 523 and the discovery and development of Qinghaosu (Artemisinin). Guangzhou: Yangcheng Evening News Publisher; 2006. (in Chinese)

    Google Scholar 

  80. Li Y, Wu YL. A golden phoenix arising from the herbal net–a review and reflection on the study of antimalarial drug artemisinin. Front Chem Chin. 2010;5:357–422. (in Chinese)

    Article  Google Scholar 

  81. Liu JM, Ni MY, Fan JF, et al. Structure and reactions of arteannuin. Acta Chim Sin. 1979;37:129–43. (in Chinese)

    CAS  Google Scholar 

  82. Li Y. Qinghaosi (Artemisinin): chemistry and pharmacology. Acta Pharmacol Sin. 2012;33:1141–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  83. Li Y, Yu PL, Chen YX, et al. Synthesis of some derivatives of artemisinin. Chin Sci Bull. 1979;24:667–9. (in Chinese)

    Article  CAS  Google Scholar 

  84. Li Y, Yu PL, Chen YX, et al. Studies on analogs of artemisinin I. the synthesis of ethers, carboxylic esters and carbonates of dihydroartemisinine. Acta Pharm Sin. 1981;16:429–39. (in Chinese)

    CAS  Google Scholar 

  85. Le WJ, You JQ, Mei JY. Chemotherapeutic effect of artesunate in experimental schistosomiasis. Acta Pharm Sin. 1983;18:619–21. (in Chinese)

    CAS  Google Scholar 

  86. Utzinger J, Xiao SH, Keiser J, et al. Current progress in the development and use of artemether for chemoprophylaxis of major human schistosome parasites. Curr Med Chem. 2001a;8:1841–60.

    Article  CAS  PubMed  Google Scholar 

  87. Utzinger J, Keiser J, Xiao SH, et al. Combination chemotherapy of schistosomiasis in laboratory studies and clinical trials. Antimicrob Agents Chemother. 2003;47:1487–95.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  88. Utzinger J, Chollet J, You J, et al. Effect of combined treatment with praziquantel and artemether on Schistosoma japonicum and Schistosoma mansoni in experimentally infected animals. Acta Trop. 2001b;80:9–18.

    Article  CAS  PubMed  Google Scholar 

  89. Hou XY, McManus DP, Gray DJ, et al. A randomized, double-blind, placebo-controlled trial of safety and efficacy of combined praziquantel and artemether treatment for acute schistosomiasis japonica in China. Bull World Health Organ. 2008;86:788–95.

    Article  PubMed  PubMed Central  Google Scholar 

  90. Liu R, Dong HF, Guo Y, et al. Efficacy of praziquantel and artemisinin dervatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis. Parasit Vectors. 2011;4:201.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  91. Wu Lj XPS, Xuan YX, et al. Experimental studies on the prophylactic effect of artesunate in early treatment of schistosomiasis by oral administration. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 1995;7:129–33. (in Chinese)

    Google Scholar 

  92. Wu LJ, Xu PS, Fang JT, et al. Experimental study on the prophylaxis of artesunate against acute schistosomiasis. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 1997;9:284–6. (in Chinese)

    Google Scholar 

  93. Xiao CS, Zhao XY, Liu NP, et al. Effect of artesunate and praziquantel in the prevention of schistosomiasis. Prev Med J PLA Chin. 2000;18:120–1. (in Chinese)

    Google Scholar 

  94. Wu L, Li S, Xuan Y, et al. Field application of artesunate in prophylaxis of schistosomiasis: an observation of 346 cases. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 1995;7:323–7. (in Chinese)

    Google Scholar 

  95. Li SW, Wu LJ, Zhang SJ, et al. Study on the optimal scheme and spreading application of artesunate on prevention of schistosomiasis japonica. Chin Med News. 2002;10:14–5. (in Chinese)

    CAS  Google Scholar 

  96. Andrews P, Thyssen J, Lorke D. The biology and toxicology of molluscicides Bayluscide. Pharmac Ther. 1982;19:245–95.

    Article  CAS  Google Scholar 

  97. Tian XG, Pan XP, Ke ZM, et al. Study on molluscicide effect of niclosamide with different methods in the field. J Trop Dis Parasitol. 2007;5:97–8. (in Chinese)

    Google Scholar 

  98. Dai JR, Li HJ, Shen XH, et al. Study on molluscicidal effect of suspension concentrate of niclosamide ethanolamine salt. Chin J Schisto Control. 2009;21:83–6. (in Chinese)

    CAS  Google Scholar 

  99. Jiang L, Li SF, Li XS, et al. Preparation of niclosamide ethanolamine nano-suspension and its molluscicidal effect. Chin J Schisto Control. 2006;19:102–6. (in Chinese)

    Google Scholar 

  100. Xi WP, Huang YX. Cute toxicity to brachydanio rerio of qiangluocide powder. Chin J Schisto Control. 2004;16:63–4. (in Chinese)

    Google Scholar 

  101. Zhu HQ, Zhong B, Cao CL, et al. Molluscicidal effect of Rongbao powder in schistosomiasis mountainous areas. Chin J Schisto Control. 2007;19:212–6. (in Chinese)

    Google Scholar 

  102. Lv GL, Wei WY, Li GP, et al. Observation on long-term field molluscicidal effects of Rongbao. Pract Prev Med. 2006;13:1462–4. (in Chinese)

    Google Scholar 

  103. Li GP, Hu PC, Wei WY, et al. Effect of Rongya in killing Oncomelania hupensis and its toxicity to fresh water fish. Chin Trop Med. 2009;9:1010–1. (in Chinese)

    CAS  Google Scholar 

  104. Zhu D, Zhou XN, Zhang SQ, et al. Study on the molluscicidal effect of META-Li against Oncomelania hupensis. Chin J Parasit Dis. 2006;24:200–3. (in Chinese)

    Google Scholar 

  105. Zhang ZH, Fang R, Yu B, et al. Field evaluation of a novel plant molluscicide “Luo-wei” against Oncomelania hupensis snails II Molluscicidal effect in the field of lake areas in Hanchuan City. Hubei Province Chin J Schisto Control. 2013;25:481–4. (in Chinese)

    CAS  Google Scholar 

  106. Zhou Y, Wang ZM, Zhang B, et al. Field evaluation of a novel plant molluscicide “Luo-wei” against the snail Oncomelania hupensis III Molluscicidal effect by spraying method in hilly regions. Chin J Schisto Control. 2013;25:495–7. (in Chinese)

    CAS  Google Scholar 

  107. Shu F, Chen SY, Xie WP, et al. Field evaluation of a novel plant molluscicide “Luo-wei” against Oncomelania hupensis IV Molluscicidal effect in field of river beach in Dongzhi County. Anhui Province Chin J Schisto Control. 2013;25:623–6. (in Chinese)

    CAS  Google Scholar 

  108. Chen L, Guo DY, Ge AQ, et al. Comparison of four kinds of snail-killing compounds. Biotechnology. 2014;27. (in Chinese)

    Google Scholar 

  109. Han BX, Chen J, Hao L, et al. Molluscicidal effect of endophyte LL3026 from buddleia lindleyana against Oncomelania hupensis. Chin J Parasit Dis. 2010;28:210–3. (in Chinese)

    Google Scholar 

  110. Utzinger J, Zhou XN, Chen MG, et al. Conquering schistosomiasis in China: the long march. Acta Trop. 2005;96:69–96.

    Article  PubMed  Google Scholar 

  111. Yang GJ, Gemperli A, Vounatsou P, et al. A growing degree-days based time-series analysis for prediction of Schistosoma japonicum transmission in Jiangsu province. China Am J Trop Med Hyg. 2006;75:549–55.

    Article  PubMed  Google Scholar 

  112. Zhou XN, Malone JB, Kristensen TK, et al. Application of geographic information systems and remote sensing to schistosomiasis control in China. Acta Trop. 2001;79:97–106.

    Article  CAS  PubMed  Google Scholar 

  113. Yang GJ, Vounatsou P, Zhou XN, et al. A review of geographic information system and remote sensing with applications to the epidemiology and control of schistosomiasis in China. Acta Trop. 2005;96:117–29.

    Article  PubMed  Google Scholar 

  114. Chen Z, Zhou XN, Yang K, et al. Strategy formulation for schistosomiasis japonica control in different environmental settings supported by spatial analysis: a case study from China. Geospat Health. 2007;1:223–31.

    Article  PubMed  Google Scholar 

  115. Yang K, Wang XH, Yang GJ, et al. An integrated approach to identify distribution of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, in a mountainous region in China. Int J Parasitol. 2008;38:1007–16.

    Article  PubMed  Google Scholar 

  116. Zhou XN, Yang K, Hong QB, et al. Prediction of the impact of climate warming on transmission of schistosomiasis in China. Chin J Parasitol Parasit Dis. 2004;22:262–5.

    Google Scholar 

  117. Hong QB, Wen LY, Zhong B, et al. Applicable technology: a driver to eliminate schistosomiasis in China. Insights gained from the first forum on schistosomiasis control in China. Chin J Schisto. Control. 2015;27:447–50. (in Chinese)

    Google Scholar 

  118. Sun LP, Wang W, Hong QB, et al. Approaches being used in the national schistosomiasis elimination programme in China: a review. Int Dis Poverty. 2017;6:55.

    Article  Google Scholar 

  119. Gao Y, Yang J, Sun LP, et al. Study on schistosomiasis control measures in mobile boat fishermen I harmless public toilets at fixed anchor points. Chin J Schisto Control. 2008;20:102–5. (in Chinese)

    Google Scholar 

  120. Wang FB, Ma YC, Sun LP, et al. Integration and demonstration of key techniques in surveillance and fore-cast of schistosomiasis in Jiangsu Province III development of a machine simultaneously integrating mechanized environmental cleaning and automatic mollusciciding. Chin J Schisto Control. 2016;28:5–10. (in Chinese)

    Google Scholar 

  121. Jiang YF, Wang J, Ji ZP, et al. Development of method and detector for niclosamide detection in field. Chin J Schisto Control. 2009;21:209–11. (in Chinese)

    CAS  Google Scholar 

  122. Zhu HQ, Zhang GR, Zhong B, et al. Molluscicidal effect of film on ditches in mountainous schistosomiasis endemic regions. Chin J Schisto Control. 2011;23:128–32. (in Chinese)

    Google Scholar 

  123. Sun LP, Liang YS, Tian ZX, et al. Surveillance and forecast system of schistosomiasis in Jiangsu Province II establishment of real-time operation and expression platform based on Google earth. Chin J Schisto Control. 2009;21:368–72. (in Chinese)

    Google Scholar 

  124. Sun LP, Liang YS, Wu HH, et al. A Google earth-based surveillance system for schistosomiasis japonica implemented in the lower reaches of the Yangtze River. China Parasit Vectors. 2011;4:223.

    Article  PubMed  Google Scholar 

  125. Yang K, Sun LP, Huang YX, et al. A real-time platform for monitoring schistosomiasis transmission supported by Google earth and a web-based geographical information system. Geospat Health. 2012;6:195–203.

    Article  PubMed  Google Scholar 

  126. Liu XL, Ma YC, Wang FB. Effect of health education on schistosomiasis control in fishermen and boatmen. Chin J Schisto Control. 2009;21:424–5. (in Chinese)

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, Hangzhou, China

    Jian-feng Zhang & Li-yong Wen

  2. National Institute of Parasitic Diseases, Chinese Center for Disease control and Prevention, Shanghai, China

    Jing Xu, Wei Guan, Ying-jun Qian, Shi-zhu Li & Xiao-nong Zhou

  3. Hunan Institute of Parasitic Diseases, Yueyang, China

    Zheng-yuan Zhao, Yong-hui Zhu, Hui-lan Wang & Guang-hui Ren

  4. Jiangsu Institute of Parasitic Diseases, Wuxi, China

    Guo-jing Yang, Le-ping Sun, Qing-biao Hong & Wei Wang

Authors
  1. Jian-feng Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jing Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Li-yong Wen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zheng-yuan Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Yong-hui Zhu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hui-lan Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Guang-hui Ren
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Wei Guan
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Ying-jun Qian
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Guo-jing Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Le-ping Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Qing-biao Hong
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. Wei Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  14. Shi-zhu Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  15. Xiao-nong Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Xiao-nong Zhou .

Editor information

Editors and Affiliations

  1. National Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention, Shanghai, Shanghai, China

    Xiao-Nong Zhou

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Zhang, Jf. et al. (2022). Progress on Schistosomiasis Research in China. In: Zhou, XN. (eds) Tropical Diseases in China. Public Health in China, vol 5. Springer, Singapore. https://doi.org/10.1007/978-981-19-5707-9_4

Download citation

  • DOI: https://doi.org/10.1007/978-981-19-5707-9_4

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-5706-2

  • Online ISBN: 978-981-19-5707-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation