Abstract
Ganoderma species are a large and diverse genus of wood-rotting fungi that are found worldwide. It is made up of species that cause white rot on a wide variety of tree species. It has a long history of use as a medicinal mushroom in Asia and contains a variety of pharmacological properties associated with immunomodulatory action. It grows on decaying wood, and different components of the mushroom, including mycelia, spores, and the basidiocarps, are taken and marketed in a variety of forms, including powder, capsules, and beverages. Recent years have seen the rapid expansion of the Ganoderma enterprise, which has been aided by several efforts by academia and business. Numerous commercial products have used the bioactive components and their pharmacological activities. Thus, demand for Ganoderma mushroom as a therapeutic material is projected to increase in the near future. This is due to consumers who use dietary supplements and nutraceuticals to maintain their health and immunity. This chapter summarizes the significance, current perspectives, methodology for mushroom growth and production, and products in order to ascertain the current market status of Ganoderma mushroom products. These include strain characteristics, culture, and product processing, among others. It will serve as a significant information source for both research and commercial production.
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References
Ahmad, M. F. (2018). Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement. Biomedicine & Pharmacotherapy, 107, 507–519.
Baldrian, P., Větrovský, T., Lepinay, C., & Kohout, P. (2021). High-throughput sequencing view on the magnitude of global fungal diversity. Fungal Diversity, 114, 539–547. https://doi.org/10.1007/s13225-021-00472-y
Barshteyn, V., & Krupodorova, T. (2016). Utilization of agro-industrial waste by higher mushrooms: Modern view and trends. Journal of Microbiology, Biotechnology and Food Sciences, 05, 563–577. https://doi.org/10.15414/jmbfs.2016.5.6.563-577
Basnet, B. B., Liu, L., Bao, L., & Liu, H. (2017). Current and future perspective on antimicrobial and anti-parasitic activities of Ganoderma sp.: An update. Mycology, 8, 111–124. https://doi.org/10.1080/21501203.2017.1324529
Bernabé-gonzález, T., & Cayetano-Catarino, M. (2015). Cultivation of Ganoderma lucidum on agricultural by-products in Mexico. Micología Aplicada International, 27, 25–30.
Bharadwaj, S., Lee, K. E., Dwivedi, V. D., et al. (2019). Discovery of Ganoderma lucidum triterpenoids as potential inhibitors against Dengue virus NS2B-NS3 protease. Scientific Reports, 9, 1–12. https://doi.org/10.1038/s41598-019-55723-5
Bhosle, S., Ranadive, K., Bapat, G., et al. (2010). Taxonomy and diversity of Ganoderma from the western parts of Maharashtra (India). Mycosphere, 1, 249–262.
Bijalwan, A., Bahuguna, K., Vasishth, A., et al. (2021). Growth performance of Ganoderma lucidum using billet method in Garhwal Himalaya, India. Saudi Journal of Biological Sciences, 28, 2709–2717. https://doi.org/10.1016/j.sjbs.2021.03.030
Bishop, K. S., Kao, C. H. J., Xu, Y., et al. (2015). Phytochemistry from 2000 years of Ganoderma lucidum to recent developments in nutraceuticals. Phytochemistry, 114, 56–65. https://doi.org/10.1016/j.phytochem.2015.02.015
Cao, Y., Wu, S. H., & Dai, Y. C. (2012). Species clarification of the prize medicinal Ganoderma mushroom Lingzhi. Fungal Diversity, 56, 49–62. https://doi.org/10.1007/s13225-012-0178-5
Chen, A. W. (2002). Natural-Log Cultivation of the Medicinal Mushroom Ganoderma lucidum (reishi). The Mushroom Growers’ Newsletter.
Chen, B., Ke, B., Ye, L., et al. (2017). Isolation and varietal characterization of Ganoderma resinaceum from areas of Ganoderma lucidum production in China. Scientia Horticulturae (Amsterdam), 224, 109–114. https://doi.org/10.1016/j.scienta.2017.06.002
Chen, S., Xu, J., Liu, C., et al. (2012). Genome sequence of the model medicinal mushroom Ganoderma lucidum. Nature Communications, 3, 1–9. https://doi.org/10.1038/ncomms1923
Erkel, E. I. (2009). Yield performance of Ganoderma lucidum (Fr.) Karst cultivation on substrates containing different protein and carbohydrate sources. African Journal of Agricultural Research, 4, 1331–1333.
Fernandes, P. D. T., Chaquisse, E., & Ferrão, J. (2020). HIV and the antiviral role of mushroom nutraceuticals. Advanced Image Video Process, 8(3). https://doi.org/10.14738/aivp.83.8650
Ferreira, I. C. F. R., Heleno, S. A., Reis, F. S., et al. (2015). Phytochemistry chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. Phytochemistry, 114, 38–55. https://doi.org/10.1016/j.phytochem.2014.10.011
Flórez-Sampedro, L., Zapata, W., Orozco, L. P., et al. (2016). In vitro anti-HIV-1 activity of the enzymatic extract enriched with laccase produced by the fungi Ganoderma sp. and Lentinus sp. Vitae, 23, 109–118. https://doi.org/10.17533/udea.vitae.v23n2a03
Girmay, Z., Gorems, W., Birhanu, G., & Zewdie, S. (2016). Growth and yield performance of Pleurotus ostreatus (Jacq. Fr.) Kumm (oyster mushroom) on different substrates. AMB Express, 6, 1–7. https://doi.org/10.1186/s13568-016-0265-1
Gonzáles-Matute, R., Figlas, D., Devalis, R., et al. (2002). Sunflower seed hulls as main nutrient source for Ganoderma. Micología Aplicada International, 14, 19–24.
González, A., Cruz, M., Losoya, C., et al. (2020). Edible mushrooms as a novel protein source for functional foods. Food & Function, 11, 7400–7414. https://doi.org/10.1039/d0fo01746a
Hapuarachchi, K. K., Elkhateeb, W. A., Karunarathna, S. C., et al. (2018). Current status of global Ganoderma cultivation, products, industry and market. Mycosphere, 9, 1025–1052. https://doi.org/10.5943/mycosphere/9/5/6
Hapuarachchi, K. K., Wen, T. C., Jeewon, R., et al. (2016). Mycosphere Essays 15. Ganoderma lucidum—Are the beneficial medical properties substantiated? Mycosphere, 7, 687–715. https://doi.org/10.5943/mycosphere/7/6/1
Hleba, L., Vuković, N., Petrová, J., & Kačániová, M. (2014). Antimicrobial activity of crude methanolic extracts from Ganoderma lucidum and Trametes versicolor. Scientific Papers Animal Science and Biotechnologies, 47, 89–93.
Ho, L.-H., Asyikeen Zulkifli, N., & Tan, T.-C. (2020). Edible mushroom: Nutritional properties, potential nutraceutical values, and its utilisation in food product development. In An introduction to mushroom. IntechOpen.
Hoq, A., Islam, N., Yeasmin, M., et al. (2016). Yield and yield attributes of reishi mushroom (Ganoderma lucidum) as affected by maturity levels. World Applied Sciences Journal, 34, 942–947. https://doi.org/10.5829/idosi.wasj.2016.34.7.156699
Huang, S. T., Teng, N. C., Wang, H. H., et al. (2019). Wasted Ganoderma tsugae derived chitosans for smear layer removal in endodontic treatment. Polymers (Basel), 11, 1–9. https://doi.org/10.3390/polym11111795
Hushiarian, R., Yusof, N. A., & Dutse, S. W. (2013). Detection and control of Ganoderma boninense: Strategies and perspectives. Springerplus, 2, 1–12.
Hwang, I. W., Kim, B. M., Kim, Y. C., et al. (2018). Improvement in β-glucan extraction from Ganoderma lucidum with high-pressure steaming and enzymatic pre-treatment. Applied Biological Chemistry, 61, 235–242. https://doi.org/10.1007/s13765-018-0350-z
Jandaik, S., Rajender, S., & Mamta, S. (2013). Comparative growth characteristics and yield attributes of lingzhi or reishi medicinal mushroom, Ganoderma lucidum (higher basidiomycetes) on different substrates in India. International Journal of Medicinal Mushrooms, 15, 497–503. https://doi.org/10.1615/IntJMedMushr.v15.i5.70
Jayasinghe, C., Imtiaj, A., Hur, H., et al. (2008). Favorable culture conditions for mycelial growth of korean wild strains in Ganoderma lucidum. Mycobiology, 36, 28–33.
Jeewanthi, L. A. M. N., Ratnayake, K., & Rajapakse, P. (2017). Growth and yield of reishi mushroom [Ganoderma lucidum (Curtis) P. Karst] in different sawdust substrates. Journal of Food and Agriculture, 10(8). https://doi.org/10.4038/jfa.v10i1-2.5208
Karuppiah, S., & Ji, L. S. (2020). Ganotherapy and holistic human system is the pathway of holistic health for immediate relief for COVID19. Open Journal of Preventive Medicine, 10, 45–61. https://doi.org/10.4236/ojpm.2020.103003
Khoo, S. C., Ma, N. L., Peng, W. X., et al. (2022). Valorisation of biomass and diaper waste into a sustainable production of the medical mushroom Lingzhi Ganoderma lucidum. Chemosphere, 286, 131477. https://doi.org/10.1016/j.chemosphere.2021.131477
Khoo, S. C., Peng, W. X., Yang, Y., et al. (2020). Development of formaldehyde-free bio-board produced from mushroom mycelium and substrate waste. Journal of Hazardous Materials, 400, 123296. https://doi.org/10.1016/j.jhazmat.2020.123296
Kim, J. W., Kim, H. I. I., Kim, J. H., et al. (2016). Effects of ganodermanondiol, a new melanogenesis inhibitor from the medicinal mushroom Ganoderma lucidum. International Journal of Molecular Sciences, 17, 1–12. https://doi.org/10.3390/ijms17111798
Kumla, J., Suwannarach, N., Sujarit, K., et al. (2020). Cultivation of mushrooms and their lignocellulolytic enzyme production through the utilization of agro-industrial waste. Molecules, 25, 1–39.
Leskosek-Cukalovic, I., Despotovic, S., Lakic, N., et al. (2010). Ganoderma lucidum - Medical mushroom as a raw material for beer with enhanced functional properties. Food Research International, 43, 2262–2269. https://doi.org/10.1016/j.foodres.2010.07.014
Li, H., Tian, Y., Menolli, N., et al. (2021). Reviewing the world’s edible mushroom species: A new evidence-based classification system. Comprehensive Reviews in Food Science and Food Safety, 20, 1982–2014.
Li, S., Dong, C., Wen, H., & Liu, X. (2016). Development of Ling-zhi industry in China – Emanated from the artificial cultivation in the Institute of Microbiology, Chinese Academy of Sciences (IMCAS). Mycology, 7, 74–80. https://doi.org/10.1080/21501203.2016.1171805
Liu, Y.-c., Tang, X.-c., Hu, H.-p., et al. (2021). Genetic diversity and main functional composition of Lingzhi strains from main producing areas in China. AMB Express, 11, 119. https://doi.org/10.1186/s13568-021-01280-y
Loyd, A. L., Richter, B. S., Jusino, M. A., et al. (2018). Identifying the “Mushroom of immortality”: Assessing the Ganoderma species composition in commercial reishi products. Frontiers in Microbiology, 9, 1–14. https://doi.org/10.3389/fmicb.2018.01557
Magday, J., Jr. (2014). Optimization of mycelial growth and cultivation of fruiting body of Philippine wild strain of Ganoderma lucidum. Current Research in Environmental and Applied Mycology, 4, 162–172. https://doi.org/10.5943/cream/4/2/4
Majid, A., Maryam, T., Mohammad, F., & Fatemeh, O. (2012). Yield performance of lingzhi or reishi medicinal mushroom, Ganoderma lucidum (W.Curt.:Fr.) P. Karst. (higher basidiomycetes), using different waste materials as substrates. International Journal of Medicinal Mushrooms, 521–527. https://doi.org/10.1615/IntJMedMushr.v14.i5.110
Mehta, S., Jandaik, S., & Gupta, D. (2014). Effect of cost-effective substrates on growth cycle and yield of lingzhi or reishi medicinal mushroom, Ganoderma lucidum (Higher Basidiomycetes) from Northwestern Himalaya (India). International Journal of Medicinal Mushrooms, 16, 585–591. https://doi.org/10.1615/IntJMedMushrooms.v16.i6.80
Midot, F., Lau, S. Y. L., Wong, W. C., et al. (2019). Genetic diversity and demographic history of Ganoderma boninense in oil palm plantations of Sarawak, Malaysia inferred from ITS regions. Microorganisms, 7, 464. https://doi.org/10.3390/microorganisms7100464
Niazi, A. R., & Ghafoor, A. (2021). Different ways to exploit mushrooms: A review. All Life, 14, 450–460.
Okamoto, H., & Mizuno, T. (1997). IV. Cultivation of reishi (Ganoderma lucidum). Food Review International, 13, 370–373. https://doi.org/10.1080/87559129709541119
Pegler, D. N. (2002). Useful fungi of the world: The ling-zhi - The mushroom of immortality. Mycologist, 16, 100–101. https://doi.org/10.1017/S0269915X0200304X
Peksen, A., & Yakupoglu, Æ. G. (2009). Tea waste as a supplement for the cultivation of Ganoderma lucidum. World Journal of Microbiology and Biotechnology, 25, 611–618. https://doi.org/10.1007/s11274-008-9931-z
Postemsky, P. D., Marinangeli, P. A., & Curvetto, N. R. (2016). Recycling of residual substrate from Ganoderma lucidum mushroom cultivation as biodegradable containers for horticultural seedlings. Scientia Horticulturae (Amsterdam), 201, 329–337. https://doi.org/10.1016/j.scienta.2016.02.021
Ralte, Z., Lal, A. A., & Simon, S. (2020). Evaluation of the locally available substrates for the cultivation of Ganoderma lucidum (W.Curt.:Fr.) Karst (Reishi Mushroom) in Prayagraj, U.P. International Journal of Current Microbiology and Applied Sciences, 9, 1564–1569. https://doi.org/10.20546/ijcmas.2020.911.185
Rashad, F. M., El Kattan, M. H., Fathy, H. M., et al. (2019). Recycling of agro-wastes for Ganoderma lucidum mushroom production and Ganoderma post mushroom substrate as soil amendment. Waste Management, 88, 147–159. https://doi.org/10.1016/j.wasman.2019.03.040
Renu, T., & Brij, M. S. (2015). Deployment of indigenous wild Ganoderma lucidum for better yield on different substrates. African Journal of Agricultural Research, 10, 3338–3341. https://doi.org/10.5897/ajar2015.9866
Ritu, M., Ladhu, R., Deepesh, & Tanu, M. (2020). Ganoderma. In R. W. Weber (Ed.), Beneficial microbes in agro-ecology (pp. 625–649). Elsevier.
Rolim, L. D. N., Sales-Campos, C., Cavalcanti, M. A. D. Q., & Urben, A. F. (2014). Application of Chinese Jun-Cao technique for the production of Brazilian Ganoderma lucidum strains. Brazilian Archives of Biology and Technology, 57, 367–373. https://doi.org/10.1590/S1516-89132014005000015
Roy, S. (2015). Artificial cultivation of Ganoderma lucidum (reishi medicinal mushroom) using different sawdusts as substrates. American Journal of BioScience, 3, 178. https://doi.org/10.11648/j.ajbio.20150305.13
Seephueak, P., Preecha, C., & Seephueak, W. (2019). Effects of palm oil sludge as a supplement on Ganoderma lucidum (Fr.) Karst. cultivation. Songklanakarin Journal of Science and Technology, 41, 292–298. https://doi.org/10.14456/sjst-psu.2019.37
Sharma, C., Bhardwaj, N., Sharma, A., et al. (2019). Bioactive metabolites of Ganoderma lucidum: Factors, mechanism and broad spectrum therapeutic potential. Journal of Herbal Medicine, 17–18, 100268.
Singh, S., Harsh, N. S. K., & Gupta, P. K. (2014). A novel method of economical cultivation of medicinally important mushroom, Ganoderma lucidum. International Journal of Pharmaceutical Sciences and Research, 5, 2033–2037. https://doi.org/10.13040/IJPSR.0975-8232.5(5).2033-37
Siwulski, M., Sobieralski, K., Golak-Siwulska, I., et al. (2015). Ganoderma lucidum (Curt.: Fr.) Karst. – Health-promoting properties. A review. Herba Polonica, 61, 105–118. https://doi.org/10.1515/hepo-2015-0026
Solomon, P. W. (2010). Medicinal mushroom science: History, current status, future trends and unsolved problems. International Journal of Medicinal Mushrooms, 12, 1–16.
Subedi, K., Basnet, B. B., Panday, R., et al. (2021). Optimization of growth conditions and biological activities of nepalese Ganoderma lucidum strain Philippine. Advances in Pharmacological and Pharmaceutical Sciences, 2021, 4888979. https://doi.org/10.1155/2021/4888979
Sudheer, S., Alzorqi, I., Ali, A., Cheng, P. G., Siddiqui, Y., & Manickam, S. (2018). Determination of the biological efficiency and antioxidant potential of lingzhi or reishi medicinal mushroom, Ganoderma lucidum (Agaricomycetes), cultivated using different agro-wastes in Malaysia. International Journal of Medicinal Mushrooms, 20, 89–100. https://doi.org/10.1615/IntJMedMushrooms.2017024588
Thiribhuvanamala, G., & Krishnamoorthy, A. S. (2021). Evaluation of different lignocellulosic substrates for cultivation of medicinal mushroom Ganoderma lucidum. Journal of Environmental Biology, 42, 1314–1319. https://doi.org/10.22438/jeb/42/5/MRN-1686
Veena, S. S., & Pandey, M. (2011). Paddy straw as a substrate for the cultivation of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (W.Curt.:Fr.) P. Karst. in India. International Journal of Medicinal Mushrooms, 13, 397–400. https://doi.org/10.1615/IntJMedMushr.v13.i4.100
Venturella, G., Ferraro, V., Cirlincione, F., & Gargano, M. L. (2021). Medicinal mushrooms: Bioactive compounds, use, and clinical trials. International Journal of Molecular Sciences, 22, 1–31.
Wang, H., & Ng, T. B. (2006). Ganodermin, an antifungal protein from fruiting bodies of the medicinal mushroom Ganoderma lucidum. Peptides, 27, 27–30. https://doi.org/10.1016/j.peptides.2005.06.009
Wang, J., Cao, B., Zhao, H., & Feng, J. (2017). Emerging roles of Ganoderma lucidum in anti-aging. Aging and Disease, 8, 691–707.
Wang, X. C., Xi, R. J., Li, Y., et al. (2012). The species identity of the widely cultivated ganoderma, “G. lucidum” (ling-zhi), in China. PLoS One, 7, e40857. https://doi.org/10.1371/journal.pone.0040857
Zhang, W., Tao, J., Yang, X., et al. (2014). Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochemical and Biophysical Research Communications, 449, 307–312. https://doi.org/10.1016/j.bbrc.2014.05.019
Zhibin Lin, B. Y. (2019). Ganoderma and health: Biology, chemistry and industry. Springer.
Zhou, X. W., Su, K. Q., & Zhang, Y. M. (2012). Applied modern biotechnology for cultivation of Ganoderma and development of their products. Applied Microbiology and Biotechnology, 93, 941–963.
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Seethapathy, P., Sankaralingam, S., Muniraj, I.K., Perumal, M., Pandurangan, N. (2023). Mass Multiplication, Economic Analysis, and Marketing of Ganoderma sp. (Reishi Mushroom). In: Amaresan, N., Dharumadurai, D., Babalola, O.O. (eds) Food Microbiology Based Entrepreneurship. Springer, Singapore. https://doi.org/10.1007/978-981-19-5041-4_6
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