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Epidemiology

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Wilms’ Tumor

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Abstract

Wilms’ tumor is the most common renal tumor of childhood, affecting seven to eight cases per million person years in children. It accounts for 95% of all pediatric renal cancers and 6% of all cancers below 15 years of age. The gender-specific incidence is almost similar with slight female preponderance. The mean age of diagnosis is 41.6 months in boys and 46.9 months in girls for unilateral disease. The patients with bilateral disease present approximately 1 year before those with unilateral disease. The recent data has revealed the difference in incidence between different geographic regions and ethnic groups within that geographic region. Various case control studies have been conducted to study the role of paternal occupational exposure and maternal occupational and hormonal exposure during pregnancy. There have been inconsistencies in the pattern of exposure, and it seems unlikely that environmental exposure has any significant role to play in the pathogenesis of Wilms’ tumor. This chapter discusses the epidemiology of Wilms’ tumor in particular relation to the incidence of the tumor, geographic and ethnic variations, causative hypothesis, role of environmental factors in causation, pertinent issues in low-income countries, and the role of tumor registries.

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Author information

Authors and Affiliations

  1. Department of Pediatric Surgery, All India Institute of Medical Sciences, Jodhpur, India

    Manish Pathak

  2. Department of Pediatric Surgery, Mahatma Gandhi Mission Medical College, Navi Mumbai, India

    Dattatray Bhusare

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  1. Manish Pathak
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  2. Dattatray Bhusare
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Editor information

Editors and Affiliations

  1. Department of Pediatric Surgery, Lady Hardinge Medical College and Kalawati Saran Children’s Hospital, New Delhi, India

    Yogesh Kumar Sarin

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Pathak, M., Bhusare, D. (2022). Epidemiology. In: Sarin, Y.K. (eds) Wilms’ Tumor. Springer, Singapore. https://doi.org/10.1007/978-981-19-3428-5_2

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  • DOI: https://doi.org/10.1007/978-981-19-3428-5_2

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-3427-8

  • Online ISBN: 978-981-19-3428-5

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