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Intestinal Cancer Associated with IBD: Aim and Structure of This Book

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Atlas of Inflammatory Bowel Disease-Associated Intestinal Cancer
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Abstract

Inflammatory bowel disease (IBD)-associated intestinal cancer has been diagnosed and treated mainly in Europe and the United States. In Japan, IBD-associated colorectal cancer (CRC) has been increasing, and although ulcerative colitis (UC) surgery itself has been decreasing, CRC has been reported to account for a large proportion (34.8%) of the reasons for colorectal resection surgery [1], suggesting that countermeasures are urgently needed. Since CRC diagnosis in advanced cancer does not improve the prognosis, efficient surveillance endoscopy methodologies have been discussed to pick up early-stage cancer. In this context, the Japanese classification of early-stage colorectal cancer has been used as the Paris classification, which is a universal gross classification of superficial CRC [2]. Based on this classification, progress has been made in endoscopic diagnosis and techniques for UC-related cancers, and dye method and target biopsy is becoming the basic technique [3, 4]. However, there is a need for a more reliable diagnosis method. The reason for this is that there is an opportunity to diagnose smaller dysplasia or early-stage cancer and to seek endoscopic treatment. However, these advances have not progressed as expected because of the current limitations of endoscopic diagnostic capability and pathological diagnosis.

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References

  1. Uchino M, Ikeuchi H, Hata K, et al. Changes in the rate of and trends in colectomy for ulcerative colitis during the era of biologics and calcineurin inhibitors based on a Japanese nationwide cohorts survey. Surg Today. 2019;49:1066–73.

    Article  CAS  Google Scholar 

  2. The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc. 2003;58(6 Suppl):S3–43.

    Google Scholar 

  3. Laine L, Kaltenbach T, Barkun A, et al. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastrointest Endosc. 2015;81:489–501.

    Article  Google Scholar 

  4. Watanabe T, Ajioka Y, Mitsuyama K, et al. Comparison of targeted vs random biopsies for surveillance of ulcerative colitis-associated colorectal cancer. Gastroenterology. 2016;151(6):1122–30.

    Article  Google Scholar 

  5. Uchino M, Ikeuchi H, Hata K, et al. Intestinal cancer in patients with Crohn’s disease: a systematic review and meta-analysis. J Gastroenterol Hepatol. 2020;35:1–8.

    Google Scholar 

  6. Yano Y, Matsui T, Hirai F, et al. Cancer risk in Japanese Crohn’s disease patients: investigation of the standardized incidence ratio. J Gastroenterol Hepatol. 2013;28:1300–5.

    Article  Google Scholar 

  7. Yasukawa S, Matsui T, Yano Y, et al. Crohn’s disease-specific mortality: a 30-year cohort study at a tertiary referral center in Japan. J Gastroenterol. 2019;54(1):42–52.

    Article  Google Scholar 

  8. Jess T, Simonsen J, Jørgensen KT, et al. Decreasing risk of colorectal cancer in patients with inflammatory bowel disease over 30 years. Gastroenterology. 2012;143:375–81.

    Article  Google Scholar 

  9. Castaño-Milla C, Chaparro M, Gisbert JP. Systematic review with meta-analysis: the declining risk of colorectal cancer in ulcerative colitis. Aliment Pharmacol Ther. 2014;39(7):645–59.

    Article  Google Scholar 

  10. King D, Reulen RC, Thomas T, et al. Changing patterns in the epidemiology and outcomes of inflammatory bowel disease in the United Kingdom: 2000-2018. Aliment Pharmacol Ther. 2020;51(10):922–34. https://doi.org/10.1111/apt.15701.

    Article  PubMed  Google Scholar 

  11. Matsumoto T, Iwao Y, Igarashi M, et al. Endoscopic and chromoendoscopic atlas featuring dysplastic lesions in surveillance colonoscopy for patients with long-standing ulcerative colitis. Inflamm Bowel Dis. 2006;14:259–64.

    Article  Google Scholar 

  12. Soetikno R, Sanduleanu S, Kaltenbach T. An atlas of nonpolypoid colorectal neoplasms in inflammatory bowel disease. Gastrointest Endosc Clin N Am. 2014;24:483–520.

    Article  Google Scholar 

  13. Jaramillo E, Watanabe M, Befrits R, et al. Small, flat colorectal neoplasias in long-standing ulcerative colitis detected by high-resolution electronic video endoscopy. Gastrointest Endosc. 1996;44(1):15–22.

    Article  CAS  Google Scholar 

  14. Sugimoto S, Naganuma M, Iwao Y, et al. Endoscopic morphologic features of ulcerative colitis-associated dysplasia classified according to the SCENIC consensus statement. Gastrointest Endosc. 2017;85(3):639–46.

    Article  Google Scholar 

  15. Wang YR, Cangemi JR, Loftus EV Jr, Picco MF. Rate of early/missed colorectal cancers after colonoscopy in older patients with or without inflammatory bowel disease in the United States. Am J Gastroenterol. 2013;108:444–9.

    Article  Google Scholar 

  16. Sanduleanu S, Rutter MD. Interval colorectal cancers in inflammatory bowel disease: the grim statistics and true stories. Gastrointest Endosc Clin N Am. 2014;24(3):337–48.

    Article  Google Scholar 

  17. Choi CH, Rutter MD, Askari A, et al. Forty-year analysis of the colonoscopic surveillance program for neoplasia in ulcerative colitis: an updated overview. Am J Gastroenterol. 2015;110(7):1022–34.

    Article  Google Scholar 

  18. Yamasaki K, Matsui T, Hisabe T, et al. Retrospective analysis of the growth speed of 54 lesions of colitis-associated colorectal neoplasia. Anticancer Res. 2016;36(7):3731–40.

    PubMed  Google Scholar 

  19. Hisabe T, Matsui T, Yamasaki K, et al. Possible earlier diagnosis of ulcerative colitis-associated neoplasia: a retrospective analysis of interval cases during surveillance. J Clin Med. 2021;10:1927. https://doi.org/10.3390/jcm10091927.

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Toshiyuki Matsui .

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Matsui, T. (2022). Intestinal Cancer Associated with IBD: Aim and Structure of This Book. In: Matsui, T., Iwashita, A., Matsumoto, T., Hisabe, T., Futami, K., Tanabe, H. (eds) Atlas of Inflammatory Bowel Disease-Associated Intestinal Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-19-3413-1_1

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  • DOI: https://doi.org/10.1007/978-981-19-3413-1_1

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-3412-4

  • Online ISBN: 978-981-19-3413-1

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