Abstract
Osteoporosis is the most common metabolic bone disorder which is characterized by reduction in the bone density. Osteoporosis is called as “the silent killer” and often diagnosed after the development of fracture because it itself has no overt clinical symptoms. However, osteoporosis must not be neglected since osteoporotic fractures have enormous impacts on patients as well as the whole society. Osteoporotic fracture is the most serious clinical outcome of osteoporosis, and it is more common in women than in men, due to decreased bone mineral density (BMD) after menopause. Thus, active prevention including early diagnosis and proper treatment is crucial in the management of patients with osteoporosis. This chapter includes clinically relevant cases performed by nuclear imaging (bone scan, SPECT/CT, and PET/CT) and other correlative radiologic images for the diagnosis of the vertebral compression fracture, sacral insufficiency fracture, atypical femoral fracture, and medication-related osteonecrosis of the jaw (MRONJ) in patients with osteoporosis.
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References
Cheung C-L, Ang SB, Chadha M, Chow ES-L, Chung Y-S, Hew FL, et al. An updated hip fracture projection in Asia: the Asian Federation of Osteoporosis. Osteoporos Sarcopenia. 2018;4(1):16–21.
Elgazzar AH. Diagnosis of metabolic, endocrine and congenital bone disease. In: Elgazzar AH, editor. Orthopedic nuclear medicine. Springer; 2017. p. 111.
Schmitz A, Risse JH, Textor J. FDG-PET findings of vertebral compression fractures in osteoporosis: preliminary results. Osteoporos Int. 2002;13(9):755–61.
Cai S, Yu H, Li Y, He X, Yan L, Huang X, et al. Bone mineral density measurement combined with vertebral fracture assessment increases diagnosis of osteoporosis in postmenopausal women. Skelet Radiol. 2020;49(2):273–80.
Ahn SE, Ryu KN, Park JS, et al. Early bone marrow edema pattern of the osteoporotic vertebral compression fracture can be predictor of vertebral deformity types and prognosis? J Korean Neurosurg Soc. 2016;59:137–42.
Yang SO, Kim S, Juhng SK. Imaging diagnosis of osteoporotic fracture. J Korean Med Assoc. 2010;53:67–75.
Bredella MA, Essary B, Torriani M, Ouellette HA, Palmer WE. Use of FDG-PET in differentiating benign from malignant compression fractures. Skelet Radiol. 2008;37:405–13.
Shin DS, Shon OJ, Byun SJ, Choi JH, Chun KA, Cho IH. Differentiation between malignant and benign pathologic fractures with F-18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography. Skelet Radiol. 2008;37:415–21.
Maheshwari PR, Nagar AM, Prasad SS, Shah JR, Patkar DP. Avascular necrosis of spine: a rare appearance. Spine. 2004;29(6):E119–22.
Hamilton CB, Harnett JD, Stone NC, et al. Morbidity and mortality following pelvis ramus fractures in an older Atlantic Canadian cohort. Can J Surg. 2019;62:270–4.
Cabarrus MC, Ambekar A, Lu Y, et al. MRI and CT of insufficiency fractures of the pelvis and the proximal femur. AJR. 2008;191:995–1001.
Yoon RS, Hwang JS, Beebe KS. Long-term bisphosphonate usage and subtrochanteric insufficiency fractures? A cause for concern? J Bone Joint Surg Br. 2011;93(10):1289–95.
Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM, et al. Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2014;29(1):1–23.
Varun B, Sivakumar T, Nair BJ, Joseph AP. Bisphosphonate induced osteonecrosis of jaw in breast cancer patients: a systematic review. J Oral Maxillofac Pathol. 2012;16:210–4.
Mallya SM, Tetradis S. Imaging of radiation- and medication-related osteonecrosis. Radiol Clin N Am. 2018;56(1):77–89.
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Yang, SO., Park, J.M., Son, H.J., Cha, J.G., Chai, J.W., Oh, S.W. (2022). Osteoporosis. In: Yang, SO., Oh, S.W., Choi, Y.Y., Ryu, JS. (eds) Atlas of Nuclear Medicine in Musculoskeletal System. Springer, Singapore. https://doi.org/10.1007/978-981-19-2677-8_15
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DOI: https://doi.org/10.1007/978-981-19-2677-8_15
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