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Renal Involvement in HIV

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Pathology of Glomerular Diseases
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Abstract

The most common renal involvement in patients with HIV infection and AIDS is in the form of HIV-associated nephropathy (HIVAN); others being HIV associated immune complex-mediated glomerulonephritis (HIVIC) and noncollapsing focal segmental glomerulosclerosis. These patients usually have Cd4 counts <200 cells/cu mm. Clinically they present with significant proteinuria often in the nephrotic range and rapidly progressive renal failure.

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Further Reading

HIVAN

  • Khan S, Haragsim L, Laszik ZG. HIV-associated nephropathy. Adv Chronic Kidney Dis. 2006;13:307–13.

    Article  PubMed  Google Scholar 

  • Kopp JB, Heymann J, Winkler CA. APOL1 renal risk variants: fertile soil for HIV-associated nephropathy. Semin Nephrol. 2017;37:514–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Swanepoel CR, Atta MG, D’Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM, Conference Participants. Kidney disease in the setting of HIV infection: conclusions from a kidney disease: improving global outcomes (KDIGO) controversies conference. Kidney Int. 2018;93:545–59.

    Article  PubMed  PubMed Central  Google Scholar 

  • Wyatt CM, Klotman PE, D’Agati VD. HIV-associated nephropathy: clinical presentation, pathology and epidemiology in the era of antiretroviral therapy. Semin Nephrol. 2008;28:513–22.

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HIV Associated Crescentic Glomerulonephritis (Immune Complex Mediated)

  • Booth JW, Hamzah L, Jose S, Horsfield C, O’Donnell P, McAdoo S, Kumar EA, Turner-Stokes T, Khatib N, Das P, Naftalin C, Mackie N, Kingdon E, Williams D, Hendry BM, Sabin C, Jones R, Levy J, Hilton R, Connolly J, Post FA, HIV/CKD Study and the UK CHIC Study. Clinical characteristics and outcomes of HIV-associated immune complex kidney disease. Nephrol Dial Transplant. 2016;31:2099–107.

    Article  CAS  PubMed  Google Scholar 

  • Lescure FX, Flateau C, Pacanowski J, Brocheriou I, Rondeau E, Girard PM, Ronco P, Pialoux G, Plaisier E. HIV-associated kidney glomerular diseases: changes with time and HAART. Nephrol Dial Transplant. 2012;27:2349–55.

    Article  PubMed  Google Scholar 

  • Nobakht E, Cohen SD, Rosenberg AZ, Kimmel PL. HIV-associated immune complex kidney disease. Nat Rev Nephrol. 2016;12:291–300.

    Article  CAS  PubMed  Google Scholar 

  • Wyatt CM. Kidney disease and HIV infection. Top Antivir Med. 2017;25:13–6.

    PubMed  PubMed Central  Google Scholar 

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Gupta, P., Gupta, R.K. (2022). Renal Involvement in HIV. In: Pathology of Glomerular Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-19-1430-0_23

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  • DOI: https://doi.org/10.1007/978-981-19-1430-0_23

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-19-1429-4

  • Online ISBN: 978-981-19-1430-0

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