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X-Linked Retinoschisis

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Inherited Retinal Disease

Abstract

Since Josef Hass first described X-linked retinoschisis (XLRS, OMIM 312700) in two affected brothers in 1989 [1], XLRS has been shown to be one of the most common juvenile-onset retinal degeneration in males with an estimated prevalence of 1:5000–1:20,000 [2]. Haas believed that the disease was inflammatory in nature [1], but X-linked pattern of inheritance was demonstrated 15 years later [3], and the term “X-linked retinoschisis” was first coined in 1953 [4], which is widely accepted now.

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  1. Retina and Uveitis Clinic, Department of Ophthalmology, Severance Hospital, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Republic of Korea

    Christopher Seungkyu Lee

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  1. Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea (Republic of)

    Hyeong-Gon Yu

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Lee, C.S. (2022). X-Linked Retinoschisis. In: Yu, HG. (eds) Inherited Retinal Disease. Springer, Singapore. https://doi.org/10.1007/978-981-16-7337-5_11

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