Abstract
The gastrointestinal system is one of the most complex organ systems in our body. In addition to functioning as a digestive system, the gastrointestinal tract (GIT) houses perhaps the largest repertoire of lymphoid tissue in our body and an extensive network of neuroendocrine cells. Luminal contents are not merely restricted to the food we consume, neither enzymes, nor the products of digestion awaiting absorption or excretion, but a world of microbiota that seem to have a far-reaching effect on our well-being and ill-being. These make the gastrointestinal system one of the most fascinating systems of the human body, a system that continues to remain to be fully explored in health and disease. Pathology, as a science, is uniquely poised to contribute to the understanding of not only diseases that afflict this tract but also, as a corollary, to the normal structure and function.
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References
Hartenstein V, Martinez P. Structure, development and evolution of the digestive system. Cell Tissue Res. 2019;377:289–92.
From Lumen Biology for Majors II, Module 21, the Digestive System. https://courses.lumenlearning.com/wm-biology2/chapter/invertebrates-and-vertebrate-digestive-systems/. Provided by: Open Stax CNX. Located at: http://cnx.org/contents/185cbf87-c72e-48f5-b51e-f14f21b5eabd@10.8.under. Creative Commons License.
Montgomery RK, Mulberg AE, Grand RJ. Development of the human gastrointestinal tract: twenty years of progress. Gastroenterology. 1999;116:702–31.
Robinson JO. The history of gastric surgery. Postgrad Med J. 1960;36:706–13.
Sircus W, Flisk E, Craigs B. Milestones in the evolution of endoscopy: a short history. J R Coll Physicians Edinb. 2003;33:124–34.
Appleman HD. A curmudgeon reflects on half a century of gastrointestinal pathology. Gastroenterology. 2017;152:4–6.
Crino SF, Larghi A, Bernardoni L, Parisi A, Frulloni L, Gabbrielli A, Parcesepe P, Scarpa A, Manfrin E. Touch imprint cytology on endoscopic ultrasound fine needle biopsy provides comparable sample quality. Cytopathology. 2019;30(2):179–86.
Fabbri C, Fornelli A, Fuccio L, Giovanelli S, Tarantino I, Antonini F, Liotta R, Frazzoni L, Gusella P, La Marca M, Barresi L. High diagnostic adequacy and accuracy of the new 20G procore needle for EUS–guided tissue. Endosc Ultrasound. 2019;8(4):261–8.
Sródka A. The short history of gastroenterology. J Physiol Pharmacol. 2003;54(S3):9–21.
Kirsner JB. Blossoming of gastroenterology during the twentieth century. World J Gastroenterol. 2004;10:1541–2.
Waddingham W, Graham D, Banks M, Jansen M. The evolving role of endoscopy in the diagnosis of premalignant gastric lesions. F1000Res. 2018;7:F1000 Faculty Rev-715. https://doi.org/10.12688/f1000research.12087.1.
Shepherd NA, Valori RM. The effective use of gastrointestinal histopathology: guidance for endoscopic biopsy in the gastrointestinal tract. Front Gastroenterol. 2014;5:84–7.
Peixoto A, Silva M, Pereira P, Macedo G. Biopsies in gastrointestinal endoscopy: when and how. GE Port J Gastroenterol. 2016;23:19–27.
Teriaky A, Al Nasser A, McLean C, Gregor J, Yan B. The utility of endoscopic biopsies in patients with normal upper endoscopy. Can J Gastroenterol Hepatol. 2016:Article ID 3026563. https://doi.org/10.1155/2016/3026563.
Li H, Hou X, Lin R, Fan M, Pang S, Jiang L, Liu Q, Fu L. Advanced endoscopic methods in gastrointestinal diseases: a systematic review. Quant Imaging Med Surg. 2019;9:905–20.
Xue Y, Farris AB, Quigley B, Krasinskas A. The impact of new technologic and molecular advances in the daily practice of gastrointestinal and hepatobiliary pathology. Arch Pathol Lab Med. 2017;141:517–27.
Wang DH, Park JY. Precision medicine in gastrointestinal pathology. Arch Pathol Lab Med. 2016;140:449–60.
Calderaro J, et al. Artificial intelligence-based pathology for gastrointestinal and hepatobiliary cancers. Gut. 2021;70:1183–93.
Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI. Deep learning can predict microsattelite instability directly from histology in gastrointestinal cancer. Nat Med. 2019;25(7):1054–6.
Norgeot B, Glicksberg BS, Butte AJ. A call for deep-learning healthcare. Nat Med. 2019;25(1):14–5.
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The authors agree to the fact that all biopsy procedures and surgical resections were performed after taking informed consent from respective patients as per the individual Institutional policies, which also includes consent for publishing the unidentified clinical images for publication or research purposes. The authors also declare no conflict of interest.
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Datta Gupta, S., Banerjee, M. (2022). Perspectives in Gastrointestinal Tract Pathology. In: Das, P., Majumdar, K., Datta Gupta, S. (eds) Surgical Pathology of the Gastrointestinal System. Springer, Singapore. https://doi.org/10.1007/978-981-16-6395-6_1
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DOI: https://doi.org/10.1007/978-981-16-6395-6_1
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