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Biotechnological Interventions in Developing Vaccines Against Aeromonas Infection in Aquaculture

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Biotechnological Advances in Aquaculture Health Management

Abstract

Vaccination is one of the most effective means for disease prevention and control in any living system, and aquatic organisms are no exception. In aquaculture, the sustainability is at stake due to emergence and reemergence of infectious diseases. Among several pathogens Aeromonas species such as A. hydrophila, A. salmonicida, A. sorbia, A. bestiarum and A. veronii are the major fish pathogens that cause severe economic loss in many fish species rangingĀ from freshwater to marine water. Over the years, several attempts have been made to develop vaccines against different Aeromonas species that includes the use of inactivated form, live attenuated, its toxins, or surface antigens, outer membrane proteins, lipopolysaccharide-based vaccines against different Aeromonas species. However, the modern biotechnological tools together with reverse vaccinology approaches have opened a new era in the fieldĀ of aquatic vaccinology to formulate, develop and deliver different types of recombinant vaccines which can induce effective immunoresponses in diversified fish species to fight against Aeromoniasis.

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Nayak, S.K., Dash, J.P., Dutta, P. (2021). Biotechnological Interventions in Developing Vaccines Against Aeromonas Infection in Aquaculture. In: Gupta, S.K., Giri, S.S. (eds) Biotechnological Advances in Aquaculture Health Management . Springer, Singapore. https://doi.org/10.1007/978-981-16-5195-3_5

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