Abstract
The efficient use of xylose represents one of the most important pillars for the economic development of converting lignocellulosic biomass into value-added by-products with potential use in various activities, such as pharmaceutical, food, or biofuel industries. The conversion of lignocellulosic biomass into bioproducts of industrial value needs to be subjected to pretreatment, enzymatic hydrolysis, fermentation, and distillation or purification step. Xylose is one of the main sugars obtained by hydrolysis of biomass hemicellulose fraction. However, xylose metabolism is restricted to a few microorganisms. This makes it difficult to establish an industrial scale of production to obtain value-added products. In addition, the use of lignocellulosic pretreatment can result in sugar degradation products: furfural (sugar pentose degradation) and 5-hydroxymethyl furfural (5-HMF) (sugar hexoses degradation); formic and levulinic acids from the degradation of furfural and 5-HMF and acetic acid from the acetyl group structures of hemicellulose; and phenolics compounds released from lignin. All of these compounds are related to losses in the fermentation process. Therefore, it is important to define the best strategies for choosing a pretreatment in order to obtain high sugar release and low conversion of contaminants. Processes that aim at detoxifying the fermentative medium must be carried out. In addition, it is necessary to establish ideal cultivation conditions, such as the concentration of dissolved oxygen and pH regulation of the médium, which controls that lead to better xylose conversion rates. Studies have been conducted with potential pentose fermenting microorganisms, such as Scheffersomyces stipitis, Spathaspora hagerdaliae, Candida shehate (ethanol production); Meyerozyma guilliermondii; Spathaspora passalidarum (xylitol production); Klebsiella oxytoca; Klebsiella pneumonia; Bacillus licheniformis (2,3-butanediol (BDO) production). Therefore, research should be focused on genetic changes in yeast strains, for the production of high-value compounds as ways to establishing gains of the biofuels production, chemicals, and food. This chapter discusses the main implications involving the conversion of hemicellulose sugar into value-added products and the main microorganisms used in these processes.
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References
Almeida JRM, Modig T, Peterson A, Hänh-Hagerdal B, Lidén G, Gorwa-Grauslund MF (2007) Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae. J Chem Technol Biotechnol 82:340–349. https://doi.org/10.1002/jctb.1676
Alokika A, Kumar A, Kumar V, Singh B (2021) Cellulosic and hemicellulosic fractions of sugarcane bagasse: potential, challenges and future perspective. Int J Biol Macromol 169:564–582. https://doi.org/10.1016/j.ijbiomac.2020.12.175
Alves LA, Felipe MGA, Silva JBAE, Silva SS, Prata AMR (1998) Pretreatment of sugarcane bagasse hemicellulose hydrolysate for xylitol production by Candida guilliermondii. In: Finkelstein M, Davison BH (eds) Biotechnology for fuels and chemicals. Applied Biochemistry and Biotechnology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-1814-2_9
Alves RC, Melati RB, Casagrande GMS, Contiero J, Pagnocca FC, Brienzo M (2020) Sieving process selects sugarcane bagasse with lower recalcitrance to xylan solubilization. J Chem Technol Biotechnol 96:327–334. https://doi.org/10.1002/jctb.6541
Antunes FAF, Chandel AK, Santos JC, Lacerda TM, Dussán KJM, Silva DDV, Tagliaferro GV, Milessi TSS, Marcelino PRF, Brumano LP, Terán-Hilares R, Silvio SS (2018) Bioethanol: an overview of production possibilities. In: Brienzo M (ed) Bioethanol and beyond—advances in production process and future directions. Nova Science, Hauppauge. ISBN: 978-1-53613-478-0
Barsanti L, Gualtieri P (2014) Algae: anatomy, biochemistry, and biotechnology. CRC, Boca Raton. 361 p. ISBN 9781439867327
Behrens PW (2005) Photobioreactors and fermentors: the light and dark sides of growing algae. In: Andersen RA (ed) Algal culturing tecniques. Elsevier Academic Press, Oxford, pp 189–204
Brat D, Boles E (2013) Isobutanol production from D-xylose by recombinant Saccharomyces cerevisiae. FEMS Yeast Res 13:241–244. https://doi.org/10.1111/1567-1364.12028
Brat D, Boles E, Wiedemann B (2009) Functional expression of a bacterial xylose isomerase in Saccharomyces cerevisiae. Appl Environ Microbiol 75:2304–2311. https://doi.org/10.1128/AEM.02522-08
Brienzo M, Ferreira S, Vicentim MP, Souza W, Sant’Anna C (2014) Comparison study on the biomass recalcitrance of different tissue fractions of sugarcane culm. Bioenergy Res 7:1454–1465. https://doi.org/10.1007/s12155-014-9487-8
Brienzo M, Tyhoda L, Benjamin Y, Görgens J (2015) Relationship between physicochemical properties and enzymatic hydrolysis of sugarcane bagasse varieties for bioethanol production. N Biotechnol 32(2):253–262. https://doi.org/10.1016/j.nbt.2014.12.007
Brienzo M, Abud Y, Ferreira S, Corrales RCNR, Ferreira-Leitão VS, Souza W, Sant’Anna C (2016a) Characterization of anatomy, lignin distribution, and response to pretreatments of sugarcane culm node and internode. Ind Crop Prod 84:305–313. https://doi.org/10.1016/j.indcrop.2016.01.039
Brienzo M, Carvalho AFZ, Figueiredo FC, Neto PO (2016b) Sugarcane bagasse hemicellulose properties, extraction technologies and xylooligosaccharides production. In: Riley GL (ed) Food waste. Nova Science, Hauppauge. ISBN: 978-1-63485-025-4
Brown A, Le Feuvre P (2017) Technology roadmap: delivering sustainable bioenergy. International Energy Agency (IEA). OECD/International Energy Agency, Paris
Cadete RM, de las Heras AM, Sandström AG, Gírio CFF, Gorwa-Grauslund MF, Rosa CA, Fonseca C (2016) Exploring xylose metabolism Spathaspora species: XYL1.2 from Spathaspora passalidarum as the key for efficient anaerobic xylose fermentation in metabolic engineered Saccharomyces cerevisiae. Biotechnol Biofuels 9:167. https://doi.org/10.1186/s13068-016-0570-6
Candido JP, Claro EMT, de Paula CBC, Shimizu FL, Leite DANO, Brienzo M, Angelis DF (2020) Detoxification of sugarcane bagasse hydrolysate with diferent adsorbents to improve the fermentative process. World J Microbiol Biotechnol 36:43. https://doi.org/10.1007/s11274-020-02820-7
Canilha L, Rodrigues RCLB, Antunes FAF, Chandel AK, Milessi TSS, Felipe MGA, Silva SS (2013) Bioconversion of hemicellulose from sugarcane biomass into sustainable products. In: Chandel AK, da Silva SS (eds) Sustainable degradation of lignocellulosic biomass—techniques, applications and commercialization. InTech, Rijeka. https://doi.org/10.5772/53832
Celińska E, Grajek W (2009) Biotechnological production of 2,3-butanediol-current state and prospects. Biotechnol Adv 27(6):715–725. https://doi.org/10.1016/j.biotechadv.2009.05.002
Chacón SJ, Matias G, Vieira CFS, Ezeji TC, Filho RM, Mariano AP (2020) Enabling butanol production from crude sugarcane bagasse hemicellulose hydrolysate by batch-feeding it into molasses fermentation. Ind Crop Prod 155:112837. https://doi.org/10.1016/j.indcrop.2020.112837
Chandel AK, Chandrasekhar G, Radhika K, Ravinder R, Ravindra R (2011) Bioconversion of pentose sugars into ethanol: a review and future directions. Biotechnol Mol Biol Rev 6(1):008–020. ISSN 1538-2273
Chandel AK, Antunes FAF, Terán-Hilares R, Cota J, Ellilä S, Silveira MHL, dos Santos JC, da Silva SS (2018) Bioconversion of hemicellulose into ethanol and value-added products: commercialization, trends, and future opportunities. In: Chandel AK, MHL S (eds) Advances in sugarcane biorefinery technologies, commercialization, policy issues and paradigm shift for bioethanol and by-products. Elsevier, Amsterdam, pp 97–134. https://doi.org/10.1016/B978-0-12-804534-3.00005-7
Cheng KK, Liu Q, Zhang JA, Li JP, Xu JM, Wang GH (2010) Improved 2,3-butanediol production from corncob acid hydrolysate by fed-batch fermentation using Klebsiella oxytoca. Process Biochem 45:613–616. https://doi.org/10.1016/j.procbio.2009.12.009
Chiyanzy I, Brienzo M, García-Aparicio M, Agudelo R, Görgens J (2015) Spent coffee ground mass solubilisation by steam explosion and enzymatic hydrolysis. J Chem Technol Biotechnol 90:449–458. https://doi.org/10.1002/jctb.4313
CONAB – Companhia Nacional de Abastecimento (2019) Acomp. safra bras. cana, v. 5—Safra 2018/19, n. 4. Quarto Levantamento, Brasília, pp 1–75
Dasgupta D, Bandhu S, Adhikari DK, Ghosh D (2017) Challenges and prospects of xylitol production with whole cell bio-catalysis: a review. Microbiol Res 197:9–21. https://doi.org/10.1016/j.micres.2016.12.012
De Albuquerque TL, Da Silva IJ, De MacEdo GR, Rocha MVP (2014) Biotechnological production of xylitol from lignocellulosic wastes: a review. Process Biochem 49:1779–1789. https://doi.org/10.1016/j.procbio.2014.07.010
Delgado Arcaño Y, Valmaña García OD, Mandelli D et al (2020) Xylitol: a review on the progress and challenges of its production by chemical route. Catal Today 344:2–14. https://doi.org/10.1016/j.cattod.2018.07.060
Deutschmann R, Dekker RFH (2012) From plant biomass to bio-based chemicals: latest developments in xylan research. Biotechnol Adv 30:1627–1640. https://doi.org/10.1016/j.biotechadv.2012.07.001
Devantier R, Pedersen S, Olsson L (2005) Characterization of very high gravity etanol fermentation of corn mash. Effect of glucoamylase dosage, pre-saccharification and yeast strain. Appl Microbiol Biotechnol 68:622–629. https://doi.org/10.1007/s00253-005-1902-9
Dias MOS, Cunha MP, Jesus CDF, Rocha GJM, Pradella JGC, Rossell CEV, Maciel Filho R, Bonomi A (2011) Second generation ethanol in Brazil: can it compete with electricity production? Bioresour Technol 102:8964–8971. https://doi.org/10.1016/j.biortech.2011.06.098
Dijk MV, Erdei B, Galbe M, Nygård Y, Olsson L (2019) Strain-dependent variance in short-term adaptation effects of two xylose-fermenting strains of Saccharomyces cerevisiae. Bioresour Technol 292:121922. https://doi.org/10.1016/j.biortech.2019.121922
Du Preez JC (1994) Process parameters and environmental factors affecting D-xylose fermentation by yeasts. Enzyme Microb Technol 16:944–956. https://doi.org/10.1016/0141-0229(94)90003-5
Fao (2014) FAO Bioenergy & Food Security. Approach: implementation guide. FAO report, p 25. ISBN 978-92-5-108222-5
Felipuci JP, Schmatz A, Angelis DA, Brienzo M (2021d) Biological pretreatment improved subsequent xylan chemical solubilization. Biomass Conv Bioref. https://doi.org/10.1007/s13399-021-01506-w
Fernandes S, Murray P (2010) Metabolic engineering for improved microbial pentose fermentation. Bioeng Bugs 1(6):424–428. https://doi.org/10.4161/bbug.1.6.12724
Ferreira AD, Mussatto SI, Cadete RM, Rosa CA, Silva SS (2011) Ethanol production by a new pentose-fermenting yeast strain, Scheffersomyces stipitis UFMG-IMH 43.2, isolated from the Brazilian forest. Yeast 28:547–554. https://doi.org/10.1002/yea.1858
Freitas C, Carmona E, Brienzo M (2019) Xylooligosaccharides production process from lignocellulosic biomass and bioactive effects. Bioact Carbohydr Diet Fibre 18:100184. https://doi.org/10.1016/j.bcdf.2019.100184
Forsan C, Freitas C, Masarin F, Brienzo M (2021) Xylooligosaccharide production from sugarcane bagasse and leaf using Aspergillus versicolor endoxylanase and diluted acid. Biomass Convers Biorefin. https://doi.org/10.1007/s13399-021-01403-2
Forster-Carneiro T, Berni MD, Dorileo IL, Rostagno MA (2013) Biorefinery study of availability of agriculture residues and wastes for integrated biorefineries in Brazil. Resour Conserv Recy 77:78–88. https://doi.org/10.1016/j.resconrec.2013.05.007
Gírio FM, Fonseca C, Carvalheiro F et al (2010) Hemicelluloses for fuel ethanol: a review. Bioresour Technol 101:4775–4800. https://doi.org/10.1016/j.biortech.2010.01.088
Granström T, Leisola M (2002) Controlled transient changes reveal differences in metabolite production in two Candida yeasts. Appl Microbiol Biotechnol 58:511–516. https://doi.org/10.1007/s00253-001-0921-4
Granström T, Izumori K, Leisola M (2007) A rare sugar xylitol. Part I: the biochemistry and biosynthesis of xylitol. Appl Microbiol Biotechnol 74:227–281. https://doi.org/10.1007/s00253-006-0761-3
Guragain YN, Chitta D, Karanjikar M, Vadlani PV (2017) Appropriate lignocellulosic biomass processing strategies for efficient 2,3-butanediol production from biomass-derived sugars using Bacillus licheniformis DSM 8785. Food Bioprod Process 104:147–158. https://doi.org/10.1016/j.fbp.2017.05.010
Hahn-Hägerdal B, Lindén TS, Skoog K (1991) Ethanolic fermentation of pentoses in lignocellulose hydrolysates. Appl Biochem Biotechnol 28:131–144. https://doi.org/10.1007/BF02922595
Hahn-Hägerdal B, Jeppsson H, Skoog K, Prior BA (1994) Biochemistry and physiology of xylose fermentation by yeast. Enzym Microb Technol 16
Haldar D, Purkait MK (2020) Lignocellulosic conversion into value-added products: a review. Process Biochem 89:110–133
Harner NK, Wen X, Bajwa PK et al (2015) Genetic improvement of native xylose-fermenting yeasts for ethanol production. J Ind Microbiol Biotechnol 42:1–20. https://doi.org/10.1007/s10295-014-1535-z
Hazeena SH, Sindhu R, Pandey A, Binod P (2020) Lignocellulosic bio-refinery approach for microbial 2,3-Butanediol production. Bioresour Technol 302:122873. https://doi.org/10.1016/j.biortech.2020.122873
Hernández-Pérez AF, Arruda PV, Felipe MGA (2016) Sugarcane straw as a feedstock for xylitol production by Candida guilliermondii FTI 20037. Braz J Microbiol 47(2):489–496. https://doi.org/10.1016/j.bjm.2016.01.019
Ji XJ, Huang H, Ouyang PK (2011) Microbial 2,3-butanediol production: a state-of-the-art review. Biotechnol Adv 29:351–364. https://doi.org/10.1016/j.biotechadv.2011.01.007
Ji XJ, Huang H, Zhi-Kui N et al (2012) Fuels and chemicals from hemicellulose sugars. Adv Biochem Eng Biotechnol 128:199–224. https://doi.org/10.1007/10_2011_124
Jiang LQ, Fang Z, Guo F, Yang LB (2012) Production of 2,3-butanediol from acid hydrolysates of Jatropha hulls with Klebsiella oxytoca. Bioresour Technol 107:405–410. https://doi.org/10.1016/j.biortech.2011.12.083
Jo JH, Park YC, Jin YS, Seo JH (2017) Construction of efficient xylose-fermenting Saccharomyces cerevisiae through a synthetic isozyme system of xylose reductase from Scheffersomyces stipitis. Bioresour Technol 241:88–94. https://doi.org/10.1016/j.biortech.2017.05.091
Kahar P, Taku K, Tanaka S (2011) Enhancement of xylose uptake in 2-deoxyglucose tolerant mutant of Saccharomyces cerevisiae. J Biosci Bioeng 111(5):557–563. https://doi.org/10.1016/j.jbiosc.2010.12.020
Kang Q, Appels L, Tan T, Dewil R (2014) Bioethanol from lignocellulosic biomass: current findings determine research priorities. Sci World J 2014:298153. https://doi.org/10.1155/2014/298153
Kim D (2018) Physico-chemical conversion of lignocellulose: inhibitor effects and detoxification strategies: a mini review. Molecules 23:309. https://doi.org/10.3390/molecules23020309
Kim SR, Skerker JM, Kang W, Lesmana A, Wei N, Arkin AP, Jin YS (2013) Rational and evolutionary engineering approaches uncover a small set of genetic changes efficient for rapid xylose fermentation in Saccharomyces cerevisiae. PLoS One 8(2):e57048. https://doi.org/10.1371/journal.pone.0057048
Kim SJ, Seo SO, Jin YS, Seo JH (2014a) (a) Production of 2,3-butanediol by engineered Saccharomyces cerevisiae. Bioresour Technol 146:274–281. https://doi.org/10.1016/j.biortech.2013.07.081
Kim SJ, Seo SO, Park YC, Jin YS, Seo JH (2014b) (b) Production of 2,3-butanediol from xylose by engineered Saccharomyces cerevisiae. J Biotechnol 192:376–382. https://doi.org/10.1016/j.jbiotec.2013.12.017
Kluts IN, Brinkman MLJ, de Jong SA, Junginger HM (2017) Biomass resources: agriculture. In: Wagemann K, Tippkötter N (eds) Biorefineries. Advances in biochemical engineering/biotechnology. Springer, Berlin, p 166. https://doi.org/10.1007/10_2016_66
Kumar AK, Sharma S (2017) Recent updates on different methods of pretreatment of lignocellulosic feed stocks: a review. Bioresour Bioprocess 4:7. https://doi.org/10.1186/s4064-3-017-0137-9
Kumar V, Yadav SK, Kumar J, Ahluwalia V (2020) A critical review on current strategies and trends employed for removal of inhibitors and toxic materials generated during biomass pretreatment. Bioresour Technol 299:122633. https://doi.org/10.1016/j.biortech.2019.122633
Kummamuru B (2017) World Bioenergy Association - Global Bioenergy Statistics 2017. Available at https://worldbioenergy.org/uploads/WBA%20GBS%202017_hq.pdf. Accessed 21 Jul 2020
Kwak S, Kim SR, Xu H et al (2017) Enhanced isoprenoid production from xylose by engineered Saccharomyces cerevisiae. Biotechnol Bioeng 114:2581–2591. https://doi.org/10.1002/bit.26369
Kwak S, Jo JH, Yun EJ et al (2019) Production of biofuels and chemicals from xylose using native and engineered yeast strains. Biotechnol Adv 37:271–283. https://doi.org/10.1016/j.biotechadv.2018.12.003
Lamounier KFR, Rodrigues PO, Pasquini D, dos Santos AS, Baffi MA (2020) Ethanol production and other bioproducts by Galactomyces geotrichum from sugarcane bagasse hydrolysate. Curr Microbiol 77:738–745. https://doi.org/10.1007/s00284-019-01866-7
Lee SH, Choi BK, Kim YJ (2012a) The cariogenic characters of xylitol-resistant and xylitol-sensitive Streptococcus mutans in biofilm formation with salivary bacteria. Arch Oral Biol 57:697–703. https://doi.org/10.1016/j.archoralbio.2011.12.001
Lee SH, Kodaki T, Park YC, Seo JH (2012b) Effects of NADH-preferring xylose reductase expression on ethanol production from xylose in xylose-metabolizing recombinant Saccharomyces cerevisiae. J Biotechnol 158:184–191. https://doi.org/10.1016/j.jbiotec.2011.06.005
Li L, Li K, Wang K, Chen C, Gao C, Ma C, Xu P (2014) Efficient production of 2,3-butanediol from corn Stover hydrolysate by using a thermophilic Bacillus Licheniformis strain. Bioresour Technol 170:256–261. https://doi.org/10.1016/j.biortech.2014.07.101
Liu T, Huang S, Geng A (2018) Recombinant diploid Saccharomyces cerevisiae strain development for rapid glucose and xylose co-fermentation. Fermentation 4(3):59. https://doi.org/10.3390/fermentation4030059
Long SP et al (2015) Feedstocks for biofuels and bioenergy. In: Souza GM, Victoria RL, Joly CA, Verdade LM (eds) Bioenergy & sustainability: bridging the gaps, vol 72. SCOPE, Paris, pp 302–346. ISBN: 978-2-9545557-0-6
Manochio C, Andrade BR, Rodriguez RP, Moraes BS (2017) Ethanol from biomass: a comparative overview. Renew Sustain Energy Rev 80:743–755. https://doi.org/10.1016/j.rser.2017.05.063
Martini C, Tauk-tornisielo SM, Codato CB, Bastos RG, Ceccato-Antonini SR (2016) A strain of Meyerozyma guilliermondii isolated from sugarcane juice is able to grow and ferment pentoses in synthetic and bagasse hydrolysate media. World J Microbiol Biotechnol 32:80. https://doi.org/10.1007/s11274-016-2036-1
Martins GM, Bocchini-Martins DA, Bezzerra-Bussoli C, Pagnocca FC, Boscolo M, Monteiro DA, da Silva R, Gomes E (2018) The isolation of pentose-assimilating yeasts and their xylose fermentation potential. Braz J Microbiol 49(1):162–168. https://doi.org/10.1016/j.bjm.2016.11.014
Martins RP, Schmatz A, Freitas LA, Mutton MJR, Brienzo M (2021) Solubilization of hemicellulose and fermentable sugars from bagasse, stalks, and leaves of sweet sorghum. Ind Crop Prod 170:113813. https://doi.org/10.1016/j.indcrop.2021.113813
McMillan JD (1993) Xylose fermentation ethanol: a review. National Renewable Energy Laboratory, Golden, CO
Melati RB, Sass DC, Pagnocca FC, Brienzo M (2021) Anatomic influence of sugarcane biomass on xylan solubilization. Ind Crop Prod 164:113357. https://doi.org/10.1016/j.indcrop.2021.113357
Melati RB, Shimizu FL, Oliveira G, Pagnocca FC, Souza W, Sant’Anna C, Brienzo M (2019) Key factors affecting the recalcitrance and conversion process of biomass. Bioenergy Res 12:1–20. https://doi.org/10.1007/s12155-018-9941-0
Meyrial V, Delgenes JP, Romieu C, Moletta R, Gounot AM (1995) Ethanol tolerance and activity of plasma membrane ATPase in Pichia stipitis grown on D-xylose or on D-glucose. Enzyme Microb Technol 17:535–540. https://doi.org/10.1016/0141-0229(94)00065-Y
Milanez AY, Nyko D, Valente MS, Sousa LC, Bonomi AMFLJ, Jesus CDF, Watanabe MDB, Chagas MF, Rezende MCAF, Cavalett O, Junqueira TL, Gouvêia VLR (2015) De promessa a realidade: como o etanol celulósico pode revolucionar a indústria da cana-de-açúcar: uma avaliação do potencial competitivo e sugestões de política pública. BNDES Setorial Rio de Janeiro 41:237–294
Molinary SV, Quinlan ME (2012) In: O’Donnell K (ed) Sweeteners and sugar alternatives in food technology. Malcolm W. Kearsley, Weybridge
Mussato SI, Roberto JC (2004) Alternatives for detoxification of diluted-acid lignocellulosic hydrolyzates for use in fermentative process: a review. Bioresour Technol 93:1–10. https://doi.org/10.1016/j.biortech.2003.10.005
Nakanishi SC, Soares LB, Biazi LE, Nascimento VM, Costa AC, Rocha GJM, Ienczak JL (2017) Ethanol production from sugarcane bagasse hydrolyzate by Pathaspora passalidarum and Scheffersomyces stipitis. Biotechnol Bioeng 114(10):2211–2221. https://doi.org/10.1002/bit.26357
Novy V, Brunner B, Nidetzky B (2018) L-lactic acid production from glucose and xylose with engineered strains of Saccharomyces cerevisiae: aeration and carbon source influence yields and productivities. Microb Cell Fact 17:1–11. https://doi.org/10.1186/s12934-018-0905-z
Nweze JE, Ndubuisi I, Murata Y et al (2019) Isolation and evaluation of xylose-fermenting thermotolerant yeasts for bioethanol production. Biofuels:1–10. https://doi.org/10.1080/17597269.2018.1564480
Palmqvist E, Hahn-Hägerdal B (2000) Fermentation of lignocellulosic hydrolysates. II: Inhibitors and mechanisms of inhibition. Bioresour Technol 74:25–33. https://doi.org/10.1016/S0960-8524(99)00161-3
Passoth V, Sandgren M (2019) Biofuel production from straw hydrolysates: current achievements and perspectives. Appl Microbiol Biotechnol 103:5105–5116. https://doi.org/10.1007/s00253-019-09863-3
Perna MSC, Bastos RG, Cecatto-Antonini SR (2018) Single and combined effects of acetic acid, furfural, and sugars on the growth of the pentose-fermenting yeast Meyerozyma guilliermondii. 3 Biotech 8:119. https://doi.org/10.1007/s1320-5-018-1143-0
Prior BA, Kilian SG, Du Preez JC (1989) Fermentation of D-xylose by the yeasts Candida shehatae and Pichia stipitis: prospects and problems. Process Biochem 24(1):21–32
Pulicharla R, Lonappan L, Brar SK, Verma M (2016) Production of renewable C5 platform chemicals and potential applications. Elsevier, Amsterdam
Rastogi M, Shrivastava S (2017) Recent advances in second generation bioethanol production: an insight to pretreatment, saccharification and fermentation processes. Renew Sustain Energy Rev 80:330–340. https://doi.org/10.1016/j.rser.2017.05.225
Rech FR, Fontana RC, Rosa CA, Camassola M, Ayub MAZ, Dillon AJP (2019) Fermentation of hexoses and pentoses from sugarcane bagasse hydrolysates into ethanol by Spathaspora hagerdaliae. Bioprocess Biosyst Eng 42:83–92. https://doi.org/10.1007/s00449-018-2016-y
Rocha GJM, Nascimento VM, Gonçalves AR, Silva VFN, Martin C (2015) Influence of mixed sugarcane bagasse samples evaluated by elemental and physical chemical composition. Ind Crop Prod 64:52–58. https://doi.org/10.1016/j.indcrop.2014.11.003
Rodrigues RCLB, Sene L, Matos GS, Roberto IC, Pessoa A Jr, MGA F (2006) Enhanced Xylitol production by precultivation of Candida guilliermondii cells in sugarcane bagasse hemicellulosic hydrolysate. Curr Microbio 53:53–59. https://doi.org/10.1007/s00284-005-0242-4
Rodrussamee N, Sattayawat P, Yamada M (2018) Highly efficient conversion of xylose to ethanol without glucose repression by newly isolated thermotolerant Spathaspora passalidarum CMUWF1-2. BMC Microbiol 18:1–11. https://doi.org/10.1186/s12866-018-1218-4vl
Saha BC (2003) Hemicellulose bioconversion. J Ind Microbiol Biotechnol 30:279–291. https://doi.org/10.1007/s10295-003-0049-x
Sánchez J et al (2019) Biomass resources. In: Lago C, Caldés N, Lechón Y (eds) The role of bioenergy in the emerging bioeconomy. Academic Press, San Diego, CA, pp 25–111
Schmatz AA, Salazar-Bryam AM, Contiero J, Sant’Anna C, Brienzo M (2020a) (a) Pseudo-lignin content decreased with hemicellulose and lignin removal, improving cellulose accessibility, and enzymatic digestibility. Bioenergy Res 14:106–121. https://doi.org/10.1007/s12155-020-10187-8
Schmatz AA, Tyhoda L, Brienzo M (2020b) (b) Sugarcane biomass conversion influenced by lignin. Biofuels Bioprod Biorefin 14:469–480. https://doi.org/10.1002/bbb.2070
Shimizu FL, de Azevedo GO, Coelho LF, Pagnocca FC, Brieno M (2020) Minimum lignin and Xylan removal to improve cellulose accessibility. Bioenergy Res 13:775–785. https://doi.org/10.1007/s12155-020-10120-z
Silva JPA, Mussatto SI, Roberto IC, Teixeira JA (2012) Fermentation medium and oxygen transfer conditions that maximize the xylose conversion to ethanol by Pichia stipitis. Renew Energy 37:259–265. https://doi.org/10.1016/j.renene.2011.06.032
Singla A, Paroda S, Dhamija SS et al (2012) Bioethanol production from xylose: problems and possibilities. J Biofuels 3:1. https://doi.org/10.5958/j.0976-3015.3.1.004
Soares LCSR, Chandel AK, Pagnocca FC, Gaikwad SC, Rai M, Silva SS (2016) Screening of yeasts for selection of potential strains and their utilization for in situ microbial detoxification (ISMD) of sugarcane bagasse hemicellulosic hydrolysate. Indian J Microbiol 56(2):172–181. https://doi.org/10.1007/s12088-016-0573-9
Stambuk BU, Eleutherio ECA, Florez-Pardo LM, Souto-Maior AM, Bon EPS (2008) Brazilian Potencial for biomass ethanol: challenge of using hexose and pentose co-fermentation yeast strains. J Sci Ind Res 67:918–926
Taherzadeh MJ, Niklasson C, Liden G (2000) On-line control of fed-batch fermentation of dilute-acid hydrolyzates. Biotechnol Bioeng 69:330–338. https://doi.org/10.1002/1097-0290(20000805)69:33.0.CO;2-Q
Vallejos ME, Chade M, Mereles EB, Bengoechea DI, Brizuela JG, Felissia FE, Area MC (2016) Strategies of detoxification and fermentation for biotechnological production of xylitol from sugarcane bagasse. Ind Crop Prod 91:161–169. https://doi.org/10.1016/j.indcrop.2016.07.007
van der Pol EC, Bakker RR, Baets P, Eggink G (2014) By-products resulting from lignocellulose pretreatment and their inhibitory effect on fermentations for (bio) chemicals and fuels. Appl Microbiol Biotechnol 98:9579–9593. https://doi.org/10.1007/s00253-014-6158-9
Van Zyl B, Prior BA, du Preez JC (1991) Acetic acid inhibition of D-xylose fermentation by Pichia stipitis. Enzyme Microb Technol 13:82–86. https://doi.org/10.1016/0141-0229(91)90193-E
Venkateswar Rao L, Goli JK, Gentela J, Koti S (2016) Bioconversion of lignocellulosic biomass to xylitol: an overview. Bioresour Technol 213:299–310. https://doi.org/10.1016/j.biortech.2016.04.092
Wang Z, Dien BS, Rausch KD, Tumbleson ME, Singh V (2018) Fermentation of undetoxified sugarcane bagasse hydrolyzates using a two stage hydrothermal and mechanical refining pretreatment. Bioresour Technol 261:313–321. https://doi.org/10.1016/j.biortech.2018.04
Xiao-Xiong W, Hong-Ying H, De-Hua L, Yuan-Quan S (2016) The implementation of high fermentative 2,3-butanediol production from xylose by simultaneous additions of yeast extract, Na2EDTA, and acetic acid. N Biotechnol 33(1):16–22. https://doi.org/10.1016/j.nbt.2015.07.004
Zhang M, Eddy C, Deanda K, Finkelstein M, Picataggio S (1995) Metabolic engineering of a pentose metabolism pathway in Ethanologenic Zymomonas mobilis. Science 13(267):240–243. https://doi.org/10.1126/science.267.5195.240
Zhang F, Rodriguez S, Keasling JD (2011) Metabolic engineering of microbial pathways for advanced biofuels production. Curr Opin Biotechnol 22:775–783. https://doi.org/10.1016/j.copbio.2011.04.024
Zhao X, Song Y, Liu D (2011) Enzymatic hydrolysis and simultaneous saccharification and fermentation ofalkali/peracetic acid-pretreated sugarcane bagasse for ethanol and 2,3-butanediol production. Enzyme Microb Technol 49:413–419. https://doi.org/10.1016/j.enzmictec.2011.07.003
Zhao Z, Xian M, Liu M, Zhao G (2020) Biochemical routes for uptake and conversion of xylose by microorganisms. Biotechnol Biofuels 13:1–12. https://doi.org/10.1186/s13068-020-1662-x
Zheng Y, Pan Z, Zhang R (2009) Overview of biomass pretreatment for cellulosic ethanol production. Int J Agric Biol Eng 2:51. https://doi.org/10.3965/j.issn.1934-6344.2009.03.051-068
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The authors thank the São Paulo Research Foundation (FAPESP grant number 2017/22401-8; 2019/12997-6) for research support.
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Candido, J.P. et al. (2022). Hemicellulose Sugar Fermentation: Hydrolysate Challenges, Microorganisms, and Value-Added Products. In: Brienzo, M. (eds) Hemicellulose Biorefinery: A Sustainable Solution for Value Addition to Bio-Based Products and Bioenergy. Clean Energy Production Technologies. Springer, Singapore. https://doi.org/10.1007/978-981-16-3682-0_11
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