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Role of Viruses in Nanoparticles Synthesis

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Microbial Nanotechnology: Green Synthesis and Applications

Abstract

Nanotechnology has revolutionized with lots of applications in the medicinal field to prevent, detect and treat several biological problems including disease and infections. The plant virus nanoparticles (VNPs) and virus-like nanoparticles (VLPs) obtained through viral nanotechnology have become a versatile platform in several fields such as in obtaining high selectivity and specificity, optics and biosensing, drug delivery and targeting, nanocatalysis, next-generation nanoelectronics. The capsid proteins in plant viruses aid in the production of novel nanomaterials, also they can self-assemble and form well-organized icosahedral viruses with altered coat protein subunits, interior and exterior size properties. The virus interior is particularly used to protect the sensitive compounds and encapsulate them, while their exterior can be utilized to coat small molecules in a précised manner. These properties of viruses including their biocompatibility nature have led to the development of VNPs/VLPs to achieve targeted drug delivery. Plant viruses are natural immunogenic and thus they are altered to use as vaccines against various pathogens. In this chapter, we discuss their applications and role in nanoparticle synthesis to create an effective and alternate way related to both medicine and nanotechnology disciplines.

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Abbreviations

BMV:

Brome Mosaic Virus

CarMV:

Carnation Mottle Virus

CCMV:

Cowpea Chlorotic Mottle Virus

CP:

Capsid protein

CPMV :

Cowpea Mosaic Virus

CPs:

Capsid proteins

DNA:

Deoxyribonucleic acid

DOX:

Doxorubicin

EGF:

Epidermal growth factor

HCRSV:

Hibiscus Chlorotic Ringspot Virus

MP:

Movement protein

MPs:

Movement proteins

MRFV:

Maize Rayado Fino Virus

PAA:

Polyacrylic acid

PC:

Polyacid

PEG:

Polyethylene glycol

PSA:

Polystyrenesulfonic acid

PSD:

Particle size distribution

RCNMV:

Red Clover Necrotic Mottle Virus

RNA:

Ribonucleic acid

SeMV:

Sesbania Mosaic Virus

ssRNA:

Single-stranded RNA

TYMV:

Turnip Yellow Mosaic Virus

VLPs:

Virus-like particles

VNPs:

Virus-based nanoparticles

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Authors and Affiliations

  1. Department of Studies in Biotechnology, Davangere University, Shivagangothri, Davangere, Karnataka, India

    Chandrashekar Srinivasa & G. C. Kavitha

  2. Department of PG Studies and Research in Biotechnology, Sahyadri Science College, Kuvempu University, Shimoga, Karnataka, India

    M. Pallavi

  3. Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India

    Chandan Shivamallu & P. Sushma

  4. Department of Sciences, Amrita School of Arts and Sciences, Amrita Vishwa Vidyapeetham, Mysuru, Karnataka, India

    Shiva Prasad Kollur

  5. Department of Studies in Biotechnology, University of Mysore, Mysuru, Karnataka, India

    Mohammed Aiyaz

  6. King Abdullah Institute for Nanotechnology, King Saud University, Riyadh, Kingdom of Saudi Arabia

    Arun Kumar Shukla

  7. Applied Plant Pathology Laboratory, Department of Studies in Botany, University of Mysore, Manasagangotri, Mysuru, Karnataka, India

    M. Murali

  8. Department of Epidemic Disease Research, Institute for Research and Medical Consultation, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia

    Mohammad Azam Ansari

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  1. Chandrashekar Srinivasa
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  2. G. C. Kavitha
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  9. M. Murali
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  10. Mohammad Azam Ansari
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Correspondence to Chandrashekar Srinivasa .

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  1. Institute for Research & Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

    Mohammad Azam Ansari

  2. Institute for Research & Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia

    Suriya Rehman

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Srinivasa, C. et al. (2021). Role of Viruses in Nanoparticles Synthesis. In: Ansari, M.A., Rehman, S. (eds) Microbial Nanotechnology: Green Synthesis and Applications. Springer, Singapore. https://doi.org/10.1007/978-981-16-1923-6_6

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