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Numerical Simulation of Blocked Blood Vessel for Early Diagnosis of Coronary Artery Disease

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Modeling, Simulation and Optimization

Part of the book series: Smart Innovation, Systems and Technologies ((SIST,volume 206))

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Abstract

In this work, we present a numerical simulation of blocked blood vessel in a two-dimensional rectangular channel along with two different sizes of blood vessel diameters (4 and 1 mm). It is assumed that the blood flow is laminar, compressible, viscous, unsteady, non-newtonian, and the arterial wall be elastic. Simple algorithm was employed to solve the governing momentum and mass equations. More precisely, the present study analyzed the blood flow in presence of blocked blood vessel which caused by plaque deposited by fat and cholesterol accumulation on the side walls of the blood vessels. For different size of blockages, the current work investigates the blood velocity profile and pressure profile at eight different locations. Furthermore, it also presents the plaque’s deposition from the initial stage to complete arterial blockage [6–88%] and its impact on blood flow. It is found that, the pressure is more noticeable at 4 mm artery rather than 1 mm artery. The numerical simulations could be used to better understand the blockages and to detect coronary artery disease at a very early stage, which ignores the angiography.

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Correspondence to Sandip Saha .

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Saha, S., Biswas, P., Nath, S. (2021). Numerical Simulation of Blocked Blood Vessel for Early Diagnosis of Coronary Artery Disease. In: Das, B., Patgiri, R., Bandyopadhyay, S., Balas, V.E. (eds) Modeling, Simulation and Optimization. Smart Innovation, Systems and Technologies, vol 206. Springer, Singapore. https://doi.org/10.1007/978-981-15-9829-6_56

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