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Graphene Grafted Chitosan Nanocomposites and Their Applications

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Graphene Based Biopolymer Nanocomposites

Part of the book series: Composites Science and Technology ((CST))

Abstract

Proliferation in the biopolymer nanocomposites domain is a manifestation of its fringe benefit, opportunity to generate reformulations of traditional nanofillers and polymer matrix. The diversification in conservative nanocomposites and environmental congenial is eminent attributes to the excessive contamination in biota. Chitosan, a naturally derived biopolymer obtained from the exoskeleton of crustaceans, fungi, animals, plants and vegetables contemplated as a promising biodegradable polysaccharide for a range of applications mainly in tissue engineering, electronics, biomedical devices, supercapacitors food packaging, bone substitutes, and water filtration. The limitation of chitosan is its low mechanical strength and extremely high hydrophilicity which could be ameliorated by the inclusion of graphene oxide (GO) nanoparticles which results in outstanding load transfer. Due to the outstanding mechanical and antibacterial properties of chitosan, it has found versatile applications in the industrial and biomedical fields. This robust indagation will cast light on fabrication, properties and various applications of graphene reinforced chitosan polymer nanocomposite.

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References

  1. Sharma B, Malik P, Jain P (2018) Biopolymer reinforced nanocomposites: a comprehensive review. Mater Today Commun 16:353–363

    Article  CAS  Google Scholar 

  2. Sharma B, Malik P, Jain P (2019) To study the effect of processing conditions on structural and mechanical characterization of graphite and graphene oxide-reinforced PVA nanocomposite. Polym Bull 76(8):3841–3855

    Article  Google Scholar 

  3. Sharma B, Shekhar S, Gautam S, Jain P (2018) Dynamic shear rheology behavior and long term stability kinetics of reduced graphene oxide filled poly (vinyl alcohol) biofilm. Polym Testing 69:583–592

    Article  CAS  Google Scholar 

  4. Sharma B, Shekhar S, Malik P, Jain P (2018) Study of mechanism involved in synthesis of graphene oxide and reduced graphene oxide from graphene nanoplatelets. Mater Res Express 5(6):065012

    Article  Google Scholar 

  5. Zuo PP, Feng HF, Xu ZZ, Zhang LF, Zhang YL, Xia W, Zhang WQ (2013) Fabrication of biocompatible and mechanically reinforced graphene oxide-chitosan nanocomposite films. Chem Cent J 7(1):39

    Article  Google Scholar 

  6. Shao L, Chang X, Zhang Y, Huang Y, Yao Y, Guo Z (2013) Graphene oxide cross-linked chitosan nanocomposite membrane. Appl Surf Sci 280:989–992

    Article  CAS  Google Scholar 

  7. Zhang H, Yan T, Xu S, Feng S, Huang D, Fujita M, Gao XD (2017) Graphene oxide-chitosan nanocomposites for intracellular delivery of immunostimulatory CpG oligodeoxynucleotides. Mater Sci Eng C 73:144–151

    Article  Google Scholar 

  8. Kurita K, Yoshida A, Koyama Y (1988) Studies on chitin. 13. New polysaccharide/polypeptide hybrid materials based on chitin and poly (. gamma.-methyl L-glutamate). Macromolecules 21(6):1579–1583

    Google Scholar 

  9. Sharma B, Shekhar S, Gautam S, Sarkar A, Jain P (2018) Nanomechanical analysis of chemically reduced graphene oxide reinforced poly (vinyl alcohol) nanocomposite thin films. Polym Testing 70:458–466

    Article  CAS  Google Scholar 

  10. Sharma B, Gautam S, Shekhar S, Sharma R, Rajawat DS, Jain P (2019) Facile synthesis of poly (vinyl alcohol) nanocomposite & its potential application to enhance electrochemical performance. Polym Testing 74:119–126

    Article  CAS  Google Scholar 

  11. Jain P, Shekhar S, Chaudhary V (2019) Synergistic Reinforcement of Graphene Oxide-polyvinyl Alcohol Bionanocomposite to enhance mechanical performance. Res Rev J Phys 8(3):20–26

    Google Scholar 

  12. Bhasha SS, Jain P Thin films prepared using Sol Gel dip coating method. Metal Chalcogenide Nanostructures: Characteristics Synthesis 86

    Google Scholar 

  13. Jagur-Grodzinski J (2002) Electronically conductive polymers. Polym Adv Technol 13(9):615–625

    Article  CAS  Google Scholar 

  14. Ruel-Gariepy E, Chenite A, Chaput C, Guirguis S, Leroux JC (2000) Characterization of thermosensitive chitosan gels for the sustained delivery of drugs. Int J Pharm 203(1–2):89–98

    Article  CAS  Google Scholar 

  15. Croisier F, Jérôme C (2013) Chitosan-based biomaterials for tissue engineering. Eur Polymer J 49(4):780–792

    Article  CAS  Google Scholar 

  16. Paz E, Forriol F, Del Real JC, Dunne N (2017) Graphene oxide versus graphene for optimisation of PMMA bone cement for orthopaedic applications. Mater Sci Eng C 77:1003–1011

    Article  CAS  Google Scholar 

  17. Palmieri V, Papi M, Conti C, Ciasca G, Maulucci G, De Spirito M (2016) The future development of bacteria fighting medical devices: the role of graphene oxide. Expert Rev Med Devices 13(11):1013–1019

    Article  CAS  Google Scholar 

  18. Jing X, Mi HY, Napiwocki BN, Peng XF, Turng LS (2017) Mussel-inspired electroactive chitosan/graphene oxide composite hydrogel with rapid self-healing and recovery behavior for tissue engineering. Carbon 125:557–570

    Article  CAS  Google Scholar 

  19. Guo B, Sun Y, Finne-Wistrand A, Mustafa K, Albertsson AC (2012) Electroactive porous tubular scaffolds with degradability and non-cytotoxicity for neural tissue regeneration. Acta Biomater 8(1):144–153

    Article  CAS  Google Scholar 

  20. Gupta P, Sharan S, Roy P, Lahiri D (2015) Aligned carbon nanotube reinforced polymeric scaffolds with electrical cues for neural tissue regeneration. Carbon 95:715–724

    Article  CAS  Google Scholar 

  21. Shin SR, Jung SM, Zalabany M, Kim K, Zorlutuna P, Kim SB, Nikkah M, Kabhiry M, Azize M, Kong J, Wan KT, Palacios T, Dokmeci MR, Bae H, Tang X, Khademhossaini A (2013) Carbon-nanotube-embedded hydrogel sheets for engineering cardiac constructs and bioactuators. ACS Nano 7(3):2369–2380

    Article  CAS  Google Scholar 

  22. Tu TH, Cam PTN, Phong MT, Nam HM, Hieu NH (2019) Synthesis and application of graphene oxide aerogel as an adsorbent for removal of dyes from water. Mater Lett 238:134–137

    Article  CAS  Google Scholar 

  23. Khatamiana M, Divband B, Daryana M (2016) Preparation, characterization and antimicrobial property of ag+-nano Chitosan/ZSM-5: novel Hybrid Biocomposites. Nanomedicine J 3(4):268–279

    CAS  Google Scholar 

  24. Ruiz S, Tamayo JA, Delgado Ospina J, Navia Porras DP, Valencia Zapata ME, Hernandez M, Valencia CH, Zuluaga F, Grande Tovar CD (2019) Antimicrobial films based on nanocomposites of chitosan/poly (vinyl alcohol)/graphene oxide for biomedical applications. Biomolecules 9(3):109

    Google Scholar 

  25. Mahanta AK, Patel DK, Maiti P (2019) Nanohybrid Scaffold of Chitosan and Functionalized Graphene Oxide for Controlled Drug Delivery and Bone Regeneration. ACS Biomater Sci Eng 5(10):5139–5149

    Article  CAS  Google Scholar 

  26. Velazquez-Meraz O, Ledezma-Sillas JE, Carreño-Gallardo C, Yang W, Chaudhari NM, Calderon HA, Rusakova I, Hernandez-Robles FC, Herrera-Ramirez JM (2019) Improvement of physical and mechanical properties on bio-polymer matrix composites using morphed graphene. Compos Sci Technol 184:107836

    Google Scholar 

  27. Jiang Y, Gong JL, Zeng GM, Ou XM, Chang YN, Deng CH, Zhang J, Liu HY, Huang SY (2016) Magnetic chitosan–graphene oxide composite for anti-microbial and dye removal applications. Int J Biol Macromol 82:702–710

    Article  CAS  Google Scholar 

  28. Dhanavel S, Revathy TA, Sivaranjani T, Sivakumar K, Palani P, Narayanan V, Stephen A (2020) 5-Fluorouracil and curcumin co-encapsulated chitosan/reduced graphene oxide nanocomposites against human colon cancer cell lines. Polym Bull 77(1):213–233

    Article  CAS  Google Scholar 

  29. Lai KC, Hiew BYZ, Lee LY, Gan S, Thangalazhy-Gopakumar S, Chiu WS, Khiew PS (2019) Ice-templated graphene oxide/chitosan aerogel as an effective adsorbent for sequestration of metanil yellow dye. Biores Technol 274:134–144

    Article  CAS  Google Scholar 

  30. Olad A, Hagh HBK (2019) Graphene oxide and amin-modified graphene oxide incorporated chitosan-gelatin scaffolds as promising materials for tissue engineering. Compos B Eng 162:692–702

    Article  CAS  Google Scholar 

  31. Ahmed J, Mulla M, Maniruzzaman M (2019) Rheological and dielectric behavior of 3D-Printable Chitosan/Graphene Oxide Hydrogels. ACS Biomater Sci Eng

    Google Scholar 

  32. Hsan N, Dutta PK, Kumar S, Bera R, Das N (2019) Chitosan grafted graphene oxide aerogel: synthesis, characterization and carbon dioxide capture study. Int J Biol Macromol 125:300–306

    Article  CAS  Google Scholar 

  33. Samuel MS, Bhattacharya J, Raj S, Santhanam N, Singh H, Singh NP (2019) Efficient removal of Chromium (VI) from aqueous solution using chitosan grafted graphene oxide (CS-GO) nanocomposite. Int J Biol Macromol 121:285–292

    Article  CAS  Google Scholar 

  34. Shamekhi MA, Mirzadeh H, Mahdavi H, Rabiee A, Mohebbi-Kalhori D, Eslaminejad MB (2019) Graphene oxide containing chitosan scaffolds for cartilage tissue engineering. Int J Biol Macromol 127:396–405

    Article  CAS  Google Scholar 

  35. de Luna MS, Ascione C, Santillo C, Verdolotti L, Lavorgna M, Buonocore GG, Castaldo R, Filippone G, Xia J, Ambrosio L (2019) Optimization of dye adsorption capacity and mechanical strength of chitosan aerogels through crosslinking strategy and graphene oxide addition. Carbohyd Polym 211:195–203

    Article  Google Scholar 

  36. Barra A, Ferreira NM, Martins MA, Lazar O, Pantazi A, Jderu AA, Neumayer SM, Rodriguez BJ, Enachesceu M, Ferraira P, Nunes C (2019) Eco-friendly preparation of electrically conductive chitosan-reduced graphene oxide flexible bionanocomposites for food packaging and biological applications. Compos Sci Technol 173:53–60

    Article  CAS  Google Scholar 

  37. Poletti F, Favaretto L, Kovtun A, Treossi E, Corticelli F, Gazzano M, Palermo V, Zanardi C, Melucci M (2020) Electrochemical sensing of glucose by chitosan modified graphene oxide. J Phys: Mater 3(1):014011

    CAS  Google Scholar 

  38. Tavakoli M, Karbasi S, Soleymani Eil Bakhtiari S (2020) Evaluation of physical, mechanical, and biodegradation of chitosan/graphene oxide composite as bone substitutes. Polymer-Plastics Technol Mater 59(4):430–440

    Google Scholar 

  39. Valencia Zapata ME, Hernandez M, Herminsul J, Grande Tovar CD, Valencia Llano CH, Diaz Escobar JA, Vasquez-Laza B, Roman JS, Rojo L (2019) Novel bioactive and antibacterial acrylic bone cement nanocomposites modified with graphene oxide and chitosan. Int J Mol Sci 20(12):2938

    Google Scholar 

  40. Kafi MA, Paul A, Vilouras A, Hosseini ES, Dahiya RS (2019) Chitosan-Graphene Oxide based ultra-thin and flexible sensor for diabetic wound monitoring. IEEE Sens J

    Google Scholar 

  41. Tang T, Cao S, Xi C, Li X, Zhang L, Wang G, Chen Z (2020) Chitosan functionalized magnetic graphene oxide nanocomposite for the sensitive and effective determination of alkaloids in hotpot. Int J Biol Macromol

    Google Scholar 

  42. Sadjadi S, Heravi MM, Raja M (2019) Composite of ionic liquid decorated cyclodextrin nanosponge, graphene oxide and chitosan: a novel catalyst support. Int J Biol Macromol 122:228–237

    Article  CAS  Google Scholar 

  43. Wang F, Wei D, Li Y, Chen T, Mu P, Sun H, Zhu Z, Liang W, Li A (2019) Chitosan/reduced graphene oxide-modified spacer fabric as a salt-resistant solar absorber for efficient solar steam generation. J Mater Chem A 7(31):18311–18317

    Article  CAS  Google Scholar 

  44. Yang S, Zhang X, Zhang D (2019) Electrospun Chitosan/Poly (Vinyl Alcohol)/Graphene Oxide Nanofibrous Membrane with Ciprofloxacin Antibiotic Drug for Potential Wound Dressing Application. Int J Mol Sci 20(18):4395

    Article  CAS  Google Scholar 

  45. Sheshmani S, Nejabat Ghamsari H (2019) Photodegradation of acid orange 7 from aqueous solution under visible light irradiation using nanosized ZnO/chitosan/graphene oxide composite. Int J Environ Anal Chem 1–10

    Google Scholar 

  46. Omidi S, Pirhayati M, Kakanejadifard A (2020) Co-delivery of doxorubicin and curcumin by a pH-sensitive, injectable, and in situ hydrogel composed of chitosan, graphene, and cellulose nanowhisker. Carbohyd Polym 231:115745

    Article  CAS  Google Scholar 

  47. Duan J, Liu F, Kong Y, Hao M, He J, Wang J, Wang S, Liu J, Sang Y (2020) Homogeneous Chitosan/Graphene Oxide nanocomposite hydrogel-based actuator driven by efficient photothermally induced water gradients. ACS Appl Nano Mater

    Google Scholar 

  48. de Figueiredo Neves T, Dalarme NB, da Silva PMM, Landers R, Picone CSF, Prediger P (2020) Novel magnetic chitosan/quaternary ammonium salt graphene oxide composite applied to dye removal. J Environ Chem Eng 103820

    Google Scholar 

  49. Shekhar S, Anjana S, Bhasha S, Purnima J (2019) Electrochemical evaluation of functionalized graphene oxide filled PVA‐chitosan biohybrid for supercapacitor applications. J Appl Polymer Sci 48610

    Google Scholar 

  50. Rinaudo M (2006) Chitin and chitosan: properties and applications. Prog Polym Sci 31(7):603–632

    Article  CAS  Google Scholar 

  51. Shekhar S, Sharma R, Sharma S, Sharma B, Sarkar A, Jain P (2020) An exploration of electrocatalytic analysis and antibacterial efficacy of electrically conductive poly (D-Glucosamine)/graphene oxide bionanohybrid. Carbohydrate Polym 116242

    Google Scholar 

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Acknowledgements

Authors would like to pay gratitude to Department of Chemisitry, Netaji Subhas University of Technology, Delhi, India.

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Authors and Affiliations

  1. Department of Chemistry, Netaji Subhas University of Technology, Delhi, India

    Bhasha Sharma, Shashank Shekhar, Purnima Jain & Reetu Sharma

  2. Bhashakaracharya College of Applied Science, University of Delhi, Delhi, India

    K. K. D. Chauhan

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  1. Bhasha Sharma
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  2. Shashank Shekhar
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  3. Purnima Jain
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  4. Reetu Sharma
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  5. K. K. D. Chauhan
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Correspondence to Bhasha Sharma .

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Editors and Affiliations

  1. Department of Chemistry, Netaji Subhas University of Technology, New Delhi, Delhi, India

    Bhasha Sharma

  2. Department of Chemistry, Netaji Subhas University of Technology, New Delhi, Delhi, India

    Purnima Jain

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Sharma, B., Shekhar, S., Jain, P., Sharma, R., Chauhan, K.K.D. (2021). Graphene Grafted Chitosan Nanocomposites and Their Applications. In: Sharma, B., Jain, P. (eds) Graphene Based Biopolymer Nanocomposites. Composites Science and Technology . Springer, Singapore. https://doi.org/10.1007/978-981-15-9180-8_7

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