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Role of In Vivo Confocal Microscopy in the Diagnosis of Microbial Keratitis

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Infections of the Cornea and Conjunctiva

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Abstract

In vivo confocal microscopy (IVCM) is a noninvasive tool that potentially enables rapid diagnosis of infective keratitis, particularly in cases of Acanthamoeba or fungal keratitis. Nonspecific signs of infection include the presence of leukocytes and Langerhans cells, which can sometimes be difficult to distinguish from pathogenic organisms. This chapter discusses the IVCM morphological features and the diagnostic sensitivity and specificity of IVCM for various types of infective keratitis. The role of IVCM in assessing prognosis and monitoring the effect of treatment is also discussed.

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Authors and Affiliations

  1. Department of Ophthalmology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand

    Dipika V. Patel

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  1. Dipika V. Patel
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Correspondence to Dipika V. Patel .

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Editors and Affiliations

  1. Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India

    Sujata Das

  2. Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Vishal Jhanji

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Patel, D.V. (2021). Role of In Vivo Confocal Microscopy in the Diagnosis of Microbial Keratitis. In: Das, S., Jhanji, V. (eds) Infections of the Cornea and Conjunctiva. Springer, Singapore. https://doi.org/10.1007/978-981-15-8811-2_17

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  • DOI: https://doi.org/10.1007/978-981-15-8811-2_17

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-8810-5

  • Online ISBN: 978-981-15-8811-2

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