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Argus II Prosthetic Vision

Abstract

The Argus II Retinal Prosthesis is the first, and to date only, artificial visual implant commercially approved by the U.S. Food and Drug Administration (FDA). It is indicated for patients with end-stage retinitis pigmentosa (RP) in both eyes.

The Argus II system includes an external component, which consists of a camera, a video processing unit and a transmitting coil, and an internal component, which consists of a receiving coil, an electronics case, and the epiretinal microelectrode array. Images captured by the camera are converted to electronic signals, and then wirelessly transmitted to the implant. The signals are recovered by the internal electronics and delivered to the microelectrode array, where electrical stimulation pulses induce cellular responses in the retina.

Careful preoperative evaluation and accurate operative procedures are the key in achieving the optimal effect of this implant. Candidates for surgery must be carefully selected to ensure that they fulfill the surgical inclusion criteria and have realistic expectations of the level of vision they might gain, and they must be fully committed to undergoing visual rehabilitation and training with Argus II after surgery.

In this chapter, we cover the biomedical engineering aspects as well as the clinical aspects of the Argus II retinal prosthesis, including a brief discussion of the future development and perspectives.

Keywords

  • Argus II retinal prosthesis
  • Artificial vision
  • Retinitis pigmentosa
  • Implantation surgery
  • Clinical outcomes

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Author notes

  1. Young Hee Yoon and Lan Yue contributed equally to this work.

Authors and Affiliations

  1. Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

    Young Hee Yoon

  2. Department of Ophthalmology, USC Roski Eye Institute, University of Southern California, Los Angeles, CA, USA

    Lan Yue & Mark S. Humayun

  3. USC Institute for Biomedical Therapeutics, University of Southern California, Los Angeles, CA, USA

    Lan Yue & Mark S. Humayun

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Correspondence to Young Hee Yoon .

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Editors and Affiliations

  1. Sydney Retina Clinic and Sydney Eye Hospital, Sydney, NSW, Australia

    Dr. Andrew Chang

  2. Department of Ophthalmology and Visual Sciences, The University of Illinois at Chicago, Chicago, IL, USA

    Dr. William F. Mieler

  3. Department of Ophthalmology, Shiga University of Medical Science, Shiga, Japan

    Dr. Masahito Ohji

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Yoon, Y.H., Yue, L., Humayun, M.S. (2020). Argus II Prosthetic Vision. In: Chang, A., Mieler, W.F., Ohji, M. (eds) Macular Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-15-7644-7_34

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