Abstract
This chapter presents Molecular Imprinting Technology (MIT) as a biomimetic technique suitable as binding sites for synthetic receptor molecules and functional monomers owing to their definite interest of selectivity, sensitivity, recognition, and applications. MIT has been used extensively for the detection of pharmaceutical compounds like antibiotics which have become a global challenge due to their occurrence in the environment. Also, their detection and recognition in various industrial sample matrices are time-consuming, laborious, expensive, and very intricate. Additionally, MIT has shown great potential in producing antibacterial coatings, which could play a critical role in the fight against antibiotic-resistant bacteria especially in biomedical devices.
In this chapter, recently advanced materials used for biorecognition in terms of their morphological, physiological, and chemical properties together with their preparation techniques, are highlighted. Among the types of MITs, the sol–gel imprinting route based materials derived from polymers, ceramics, and glass which seems very promising are presented here. Additionally, the chapter investigates the strength and limitations of the sol–gel imprinting route to design antibacterial agents or receptors from pharmaceutical compounds, biomaterials, chitosan, nanomaterials, and cell implanting for biomedical applications. It was found to be economically viable with benefits good for both healthcare and environment sustainability. Therefore, MIT development presents economical application for antibacterial detection, recognition, and quantification, due to the high selectivity, rapid response, excellent stability, simplicity, and robustness of their materials when integrated with sensor detection technology.
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Acknowledgement
The authors are thankful to the Durban University of Technology, South Africa and Punjabi University, Patiala, India, for using their available resource facilities. Also, acknowledge Ms Georgina Birago Odoom for sharing her expertise in the medical field.
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Kweinor Tetteh, E., Rathilal, S., Amankwa Opoku, M., Amoah, I.D., Chollom, M.N. (2021). Molecular Imprinting Technology: A New Approach for Antibacterial Materials. In: Inamuddin, Ahamed, M.I., Prasad, R. (eds) Advanced Antimicrobial Materials and Applications. Environmental and Microbial Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-15-7098-8_15
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