Abstract
In a vast number of medical treatments, the local drug delivery is of prime importance to achieve a favorable therapeutic effect since it enhances drug bioavailability. These systems provide biological and chemical protection for drugs, reduce toxicity, increase the concentration at the site of interest, and avoid systemic exposure. The development of local systems is of great interest in both prophylactics and intensive therapies, and their formulation will depend on the characteristics of the drug and motives for actions pursued. This chapter describes the use of carrier systems, routes of administration, release mechanisms and methods, and site of action.
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This work was supported by Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México under Grant IN202320.
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Duarte, L., López-Saucedo, J., Vázquez, E., Flores-Rojas, G.G., Lopéz-Saucedo, F., Bucio, E. (2021). Antimicrobial Materials for Local Drug Delivery. In: Inamuddin, Ahamed, M.I., Prasad, R. (eds) Advanced Antimicrobial Materials and Applications. Environmental and Microbial Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-15-7098-8_12
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