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CFD Applications for Drug Delivery

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Abstract

This chapter provides the latest research trends in applications of CFD for investigating nasal drug delivery. Contributions include research and outcomes from the regulatory body, US Food Drug Administration on recent projects. Additionally, the chapter showcases the application of multiphase flow for capturing nasal spray drug delivery for improving olfactory targeting for nose-to-brain drug delivery, and nasal irrigation targeting the sinuses.

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  • DOI: 10.1007/978-981-15-6716-2_11
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Fig. 11.1

Image provided by Julia Kimbell

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Reprinted with permission of Elsevier. ©2016 Elsevier

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(Inthavong et al. [32]; reproduced with permission ©Mary-Ann Libert Publishers)

Fig. 11.7

image taken from Inthavong et al. [32]; (reproduced with permission ©Mary-Ann Libert Publishers) of distorted pencil, onion stage, tulip stage, and fully developed.

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Shrestha, K. et al. (2021). CFD Applications for Drug Delivery. In: Inthavong, K., Singh, N., Wong, E., Tu, J. (eds) Clinical and Biomedical Engineering in the Human Nose. Biological and Medical Physics, Biomedical Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-15-6716-2_11

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  • DOI: https://doi.org/10.1007/978-981-15-6716-2_11

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