Abstract
Fluorescence biosensors have seen a recent evolution by employing micro-fabrication tools and strategies to create platforms capable of achieving high throughput detection. The fluorescent response elicited from analytes can be recorded and processed with the help of conventional software and hardware tools, which can add to procedure’s versatileness. Through either the coupling of a pertinent fluorophore to different complementary particles including quantum-dots, several case-specific antibodies, analyte binding agents, or the direct functionalization of a fluorescence material, fluorescence-based biosensors allow relatively rapid and on-site detection of several analytes. This chapter provides a thorough review on the latest advancements of bio-microelectromechanical systems (BioMEMS) that operate based on the principle of fluorescence detection. A detailed comparison between the fabrication and operation of these devices along with the advantages and disadvantages of each technique are also included in this chapter.
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Acosta-Soto, L., Hosseini, S. (2021). Bio-microelectromechanical Systems (BioMEMS) in Bio-sensing Applications-Fluorescence Detection Strategies. In: BioMEMS. Lecture Notes in Bioengineering. Springer, Singapore. https://doi.org/10.1007/978-981-15-6382-9_3
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DOI: https://doi.org/10.1007/978-981-15-6382-9_3
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