Abstract
Synthesis of hydroxyapatite (HA) composite material loaded with ZnO nanoparticles is proposed. Hydroxyapatite was taken as a basic component due to its biocompatibility with bone tissue and perfect sorption properties. It could be combined with different ions and nanoparticles by simple mixing method due to its high capacity to metal ions retention. The results of studies of the structure, morphology, phase composition and antibacterial activity are presented. The minimum bactericidal concentration against E. coli and S. aureus was equal 0.034 mg/mL.
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Acknowledgements
This research supported by H2020 Marie Skłodowska-Curie Actions Grant NanoSurf 777926 and Ukraine MES Grants “Effectiveness of nanocomposite (chitosan-nanometal) antimicrobial action against multiresistant clinical strains” #0119U003577 and “Biological effectiveness of Plasma Electrolytic Oxidation and sol-gel deposition for development of functional implant surface” #0119U100823).
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Yanovska, A. et al. (2020). Synthesis, Characterization and Antibacterial Activity of Hydroxyapatite Composite Materials Loaded with ZnO Nanoparticles. In: Pogrebnjak, A., Pogorielov, M., Viter, R. (eds) Nanomaterials in Biomedical Application and Biosensors (NAP-2019). Springer Proceedings in Physics, vol 244. Springer, Singapore. https://doi.org/10.1007/978-981-15-3996-1_7
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DOI: https://doi.org/10.1007/978-981-15-3996-1_7
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