LED-Based Photoacoustic Imaging for Guiding Peripheral Minimally Invasive Procedures

Part of the Progress in Optical Science and Photonics book series (POSP, volume 7)


Photoacoustic imaging (PAI) could be useful for improving guidance of peripheral minimally invasive procedures. In this clinical application space, light emitting diodes (LEDs) have several potential advantages as excitation sources. B-mode ultrasound (US) imaging is often used for guiding invasive medical devices; however, most anatomical structures do not have unique US appearances, so the misidentification of tissues is common. There are several potential uses for LED-based PAI, including identifying procedural targets, avoiding critical tissue structures, and localising invasive medical devices relative to external imaging probes. In this chapter, we discuss the state-of-the-art of visualising tissue structures and medical devices relevant to minimally invasive procedures with PAI, key clinical considerations, and challenges involved with translating LED-based PAI systems from the benchtop to clinical use.



The authors gratefully acknowledge the support of the Wellcome/EPSRC Centre for Interventional and Surgical Sciences at the University College London, and Dr Mithun Singh for helpful feedback on this Chapter.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  1. 1.Department of Medical Physics and BioengineeringUniversity College LondonLondonUK
  2. 2.Wellcome-EPSRC Centre for Interventional & Surgical SciencesCharles Bell HouseLondonUK
  3. 3.School of Biomedical Engineering & Imaging SciencesKing’s College LondonLondonUK
  4. 4.Department of AnaesthesiaUniversity College HospitalLondonUK

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