Abstract
The expansion in population and economies leads to development of new methods of agriculture to increase the productivity and meet the demand. Chemical fertilizers and pesticides are used in large scale to increase the production, but these pose environmental impacts on different ecosystems of life. Bioactive natural products derived from microorganisms and plants serve to minimize these impact. Various compounds isolated from plant sources, algal sources, microbial sources, marine sources, etc., act as elicitors for plant defense against various sources. Majority of them are chitosan, salicylic acid (SA), benzoic acid, benzothiadiazole, alkaloids, flavonoids, terpenes, proteins, peptides, blasticidin, mildiomycin, polyoxins, phenolic compounds, etc., which act against various plant diseases caused by bacteria, fungi, and viruses. The present chapter discusses the usages of bioactive natural products as tool agonists pant disease management. These derived bioactive compounds minimize the use of chemical agents and contribute to eco-friendly sustainable agriculture practices.
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References
Abu Khalaf R, Alhusban AA, Al-Shalabi E et al (2019) Isolation and structure elucidation of bioactive polyphenols. In: Studies in natural products chemistry. Elsevier B.V., Amsterdam, pp 267–337
Aktar W, Sengupta D, Chowdhury A (2009) Impact of pesticides use in agriculture: their benefits and hazards. Interdiscip Toxicol 2:1–12. https://doi.org/10.2478/v10102-009-0001-7
Alkan N, Fortes AM (2015) Insights into molecular and metabolic events associated with fruit response to post-harvest fungal pathogens. Front Plant Sci 6:889
Altemimi A, Lakhssassi N, Baharlouei A et al (2017) Phytochemicals: extraction, isolation, and identification of bioactive compounds from plant extracts. Plan Theory 6(4):pii: E42
Amit Koparde A, Chandrashekar Doijad R, Shripal Magdum C (2019) Natural products in drug discovery. In: Pharmacognosy – medicinal plants. IntechOpen, Rijeka, Croatia
Anthoni U, Christophersen C, Nielsen PH (2001) O-benzylation of polyphenolics. Preparation of 1,2,4-tribenzyloxybenzene. Synth Commun 31:2223–2229. https://doi.org/10.1081/SCC-100104477
Atanasov AG, Waltenberger B, Pferschy-Wenzig EM et al (2015) Discovery and resupply of pharmacologically active plant-derived natural products: a review. Biotechnol Adv 33:1582–1614
Barakat A, Bagniewska-Zadworna A, Frost CJ, Carlson JE (2010) Phylogeny and expression profiling of CAD and CAD-like genes in hybrid Populus (P. deltoides × P. nigra): evidence from herbivore damage for subfunctionalization and functional divergence. BMC Plant Biol 10:100. https://doi.org/10.1186/1471-2229-10-100
Barbehenn RV, Peter Constabel C (2011) Tannins in plant-herbivore interactions. Phytochemistry 72:1551–1565
Barka EA, Vatsa P, Sanchez L et al (2016) Taxonomy, physiology, and natural products of actinobacteria. Microbiol Mol Biol Rev 80:1–43. https://doi.org/10.1128/mmbr.00019-15
Bartlett DW, Clough JM, Godwin JR et al (2002) The strobilurin fungicides. Pest Manag Sci 58:649–662. https://doi.org/10.1002/ps.520
Cardoso JC, de Oliveira MEB, Cardoso F de C (2019) Advances and challenges on the in vitro production of secondary metabolites from medicinal plants. Hortic Bras 37:124–132. https://doi.org/10.1590/s0102-053620190201
Céspedes CL, Salazar JR, Ariza-Castolo A et al (2014) Biopesticides from plants: Calceolaria integrifolia s.l. Environ Res 132:391–406. https://doi.org/10.1016/j.envres.2014.04.003
Chandler D, Bailey AS, Mark Tatchell G et al (2011) The development, regulation and use of biopesticides for integrated pest management. Philos Trans R Soc B Biol Sci 366:1987–1998. https://doi.org/10.1098/rstb.2010.0390
Chaudhary S, Kanwar RK, Sehgal A et al (2017) Progress on Azadirachta indica based biopesticides in replacing synthetic toxic pesticides. Front Plant Sci 8:610
Cheesman MJ, Ilanko A, Blonk B, Cock IE (2017) Developing new antimicrobial therapies: are synergistic combinations of plant extracts/compounds with conventional antibiotics the solution? Pharmacogn Rev 11:57–72
Chen H, Wilkerson CG, Kuchar JA et al (2005) Jasmonate-inducible plant enzymes degrade essential amino acids in the herbivore midgut. Proc Natl Acad Sci U S A 102:19237–19242. https://doi.org/10.1073/pnas.0509026102
Chen Y, Yan T, Gao C et al (2014) Natural products from the genus tephrosia. Molecules 19:1432–1458. https://doi.org/10.3390/molecules19021432
Ciko AM, Jokić S, Šubarić D, Jerković I (2018) Overview on the application of modern methods for the extraction of bioactive compounds from marine macroalgae. Mar Drugs 16(10):pii: E348. https://doi.org/10.3390/md16100348
Costa JAV, Freitas BCB, Cruz CG et al (2019) Potential of microalgae as biopesticides to contribute to sustainable agriculture and environmental development. J Environ Sci Health – Part B Pestic Food Contam Agric Wastes 54:366–375
Cowan MM (1999) Plant products as antimicrobial agents. Clin Microbiol Rev 12:564–582
Cragg GM, Newman DJ (2013) Natural products: a continuing source of novel drug leads. Biochim Biophys Acta, Gen Subj 1830:3670–3695
D’Odorico P, Davis KF, Rosa L et al (2018) The global food-energy-water nexus. Rev Geophys 56:456–531
Da Costa RJ, Voloski FLS, Mondadori RG et al (2019) Preservation of meat products with bacteriocins produced by lactic acid bacteria isolated from meat. J Food Qual 2019:1–12
Damalas CA, Eleftherohorinos IG (2011) Pesticide exposure, safety issues, and risk assessment indicators. Int J Environ Res Public Health 8:1402–1419
Davani-Davari D, Negahdaripour M, Karimzadeh I et al (2019) Prebiotics: definition, types, sources, mechanisms, and clinical applications. Foods 8(3):pii: E92
Davies J (2013) Specialized microbial metabolites: functions and origins. J Antibiot (Tokyo) 66:361–364
De Morais MG, Vaz BDS, De Morais EG, Costa JAV (2015) Biologically active metabolites synthesized by microalgae. Biomed Res Int 2015:835761
Dhifi W, Bellili S, Jazi S et al (2016) Essential oils’ chemical characterization and investigation of some biological activities: a critical review. Medicines 3:25. https://doi.org/10.3390/medicines3040025
Dias MC (2012) Phytotoxicity: an overview of the physiological responses of plants exposed to fungicides. J Bot 2012:1–4. https://doi.org/10.1155/2012/135479
Dias DA, Jones OAH, Beale DJ et al (2016) Current and future perspectives on the structural identification of small molecules in biological systems. Metabolites 6(4):46
Ding MG, Butler CA, Saracco SA et al (2008) Introduction of cytochrome b mutations in Saccharomyces cerevisiae by a method that allows selection for both functional and non-functional cytochrome b proteins. Biochim Biophys Acta Bioenerg 1777:1147–1156. https://doi.org/10.1016/j.bbabio.2008.04.029
El Gamal AA (2010) Biological importance of marine algae. Saudi Pharm J 18:1–25
Fatima N, Mukhtar U, Ihsan-Ul-Haq et al (2016) Biological evaluation of endophytic fungus chaetomium sp. NF15 of justicia adhatoda l.: a potential candidate for drug discovery. Jundishapur J Microbiol 9:e29978. https://doi.org/10.5812/jjm.29978
Felton GW, Gatehouse JA (1996) Antinutritive plant defence mechanisms. In: Biology of the insect midgut. Springer Netherlands, Dordrecht, pp 373–416
Fourati M, Smaoui S, Ennouri K et al (2019) Multiresponse optimization of pomegranate peel extraction by statistical versus artificial intelligence: predictive approach for foodborne bacterial pathogen inactivation. Evid Based Complement Alternat Med 2019:1–18. https://doi.org/10.1155/2019/1542615
Fürstenberg-Hägg J, Zagrobelny M, Bak S (2013) Plant defense against insect herbivores. Int J Mol Sci 14:10242–10297
Gakuya DW, Itonga SM, Mbaria JM et al (2013) Ethnobotanical survey of biopesticides and other medicinal plants traditionally used in Meru central district of Kenya. J Ethnopharmacol 145:547–553. https://doi.org/10.1016/j.jep.2012.11.028
Ge Y, Liu P, Yang R et al (2015) Insecticidal constituents and activity of alkaloids from Cynanchum mongolicum. Molecules 20:17483–17492. https://doi.org/10.3390/molecules200917483
George DR, Finn RD, Graham KM, Sparagano OA (2014) Present and future potential of plant-derived products to control arthropods of veterinary and medical significance. Parasit Vectors 7:28
Gouda S, Das G, Sen SK et al (2016) Endophytes: a treasure house of bioactive compounds of medicinal importance. Front Microbiol 7:1538
Grasswitz TR (2019) Integrated pest management (IPM) for small-scale farms in developed economies: challenges and opportunities. Insects 10:179. https://doi.org/10.3390/insects10060179
Grzywacz D, Stevenson PC, Mushobozi WL et al (2014) The use of indigenous ecological resources for pest control in Africa. Food Secur 6:71–86. https://doi.org/10.1007/s12571-013-0313-5
Guimarães AC, Meireles LM, Lemos MF et al (2019) Antibacterial activity of terpenes and terpenoids present in essential oils. Molecules 24(13):pii: E2471. https://doi.org/10.3390/molecules24132471
Guo Z (2017) The modification of natural products for medical use. Acta Pharm Sin B 7:119–136
Gupta PD, Birdi TJ (2017) Development of botanicals to combat antibiotic resistance. J Ayurveda Integr Med 8:266–275
Gwinn KD (2018) Bioactive natural products in plant disease control. In: Studies in natural products chemistry. Elsevier B.V., Amsterdam, pp 229–246
Ha MW, Song BR, Chung HJ, Paek S-M (2019) Design and synthesis of anti-cancer chimera molecules based on marine natural products. Mar Drugs 17:500. https://doi.org/10.3390/md17090500
Hannon M, Gimpel J, Tran M et al (2010) Biofuels from algae: challenges and potential. Biofuels 1:763–784. https://doi.org/10.4155/bfs.10.44
Harir M, Bendif H, Bellahcene M, Fortas Z, Rebecca Pogni Z (2018) Streptomyces secondary metabolites. In: Basic biology and applications of actinobacteria. IntechOpen, Rijeka, Croatia
Harish S, Saravanakumar D, Radjacommare R et al (2008) Use of plant extracts and biocontrol agents for the management of brown spot disease in rice. BioControl 53:555–567. https://doi.org/10.1007/s10526-007-9098-9
Haruta M, Pedersen JA, Constabel CP (2001) Polyphenol oxidase and herbivore defense in trembling aspen (Populus tremuloides): cDNA cloning, expression, and potential substrates. Physiol Plant 112:552–558
Hintz T, Matthews KK, Di R (2015) The use of plant antimicrobial compounds for food preservation. Biomed Res Int 2015:246264
Hossain MK, Dayem AA, Han J et al (2016) Molecular mechanisms of the anti-obesity and anti-diabetic properties of flavonoids. Int J Mol Sci 17:569
Hussain A, Ahmed I, Nazir H, Ullah I (2012) Plant tissue culture: current status and opportunities. In: Recent advances in plant in vitro culture. InTech, Rijeka, Croatia
Issa AA, Hemida M, Ohyam T (2014) Nitrogen fixing cyanobacteria: future prospect. In: Advances in biology and ecology of nitrogen fixation. InTech, Rijeka, Croatia
Iwashina T (2000) The structure and distribution of the flavonoids in plants. J Plant Res 113:287–299
Jena J, Subudhi E (2019) Microalgae: an untapped resource for natural antimicrobials. In: The role of microalgae in wastewater treatment. Springer, Singapore, pp 99–114
Jin Q, Hu W, Brown I et al (2001) Visualization of secreted Hrp and Avr proteins along the Hrp pilus during type III secretion in Erwinia amylovora and Pseudomonas syringae. Mol Microbiol 40:1129–1139. https://doi.org/10.1046/j.1365-2958.2001.02455.x
Ju J, Xie Y, Guo Y et al (2019) Application of edible coating with essential oil in food preservation. Crit Rev Food Sci Nutr 59:2467–2480. https://doi.org/10.1080/10408398.2018.1456402
Kadam SU, Tiwari BK, O’Donnell CP (2015) Extraction, structure and biofunctional activities of laminarin from brown algae. Int J Food Sci Technol 50:24–31. https://doi.org/10.1111/ijfs.12692
Khalifa SAM, Elias N, Farag MA et al (2019) Marine natural products: a source of novel anticancer drugs. Mar Drugs 17:491. https://doi.org/10.3390/md17090491
Kim JF, Beer SV (1998) HrpW of Erwinia amylovora, a new harpin that contains a domain homologous to pectate lyases of a distinct class. J Bacteriol 180(19):5203–5210
Köhl J, Kolnaar R, Ravensberg WJ (2019) Mode of action of microbial biological control agents against plant diseases: relevance beyond efficacy. Front Plant Sci 10:845. https://doi.org/10.3389/fpls.2019.00845
Koma S (2012) Plants as potential sources of pesticidal agents: a review. In: Pesticides – advances in chemical and botanical pesticides. InTech, Rijeka, Croatia
Kortbeek RWJ, van der Gragt M, Bleeker PM (2019) Endogenous plant metabolites against insects. Eur J Plant Pathol 154:67–90. https://doi.org/10.1007/s10658-018-1540-6
Kosina P, Gregorova J, Gruz J et al (2010) Phytochemical and antimicrobial characterization of Macleaya cordata herb. Fitoterapia 81:1006–1012. https://doi.org/10.1016/j.fitote.2010.06.020
Kregiel D, Berlowska J, Witonska I et al (2017) Saponin-based, biological-active surfactants from plants. In: Application and characterization of surfactants. InTech, Rijeka, Croatia
Kumar P, Kizhakkedathu JN, Straus SK (2018) Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo. Biomol Ther 8(1):pii: E4
Kumar M, Jaiswal S, Sodhi KK et al (2019) Antibiotics bioremediation: perspectives on its ecotoxicity and resistance. Environ Int 124:448–461
Künstler A, Király L, Kátay G et al (2019) Glutathione can compensate for salicylic acid deficiency in tobacco to maintain resistance to tobacco mosaic virus. Front Plant Sci 10:1115. https://doi.org/10.3389/fpls.2019.01115
Kurutas EB (2016) The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state. Nutr J 15(1):71
Lamichhane JR, Osdaghi E, Behlau F et al (2018) Thirteen decades of antimicrobial copper compounds applied in agriculture. A review. Agron Sustain Dev 38(3):28
Legentil L, Paris F, Ballet C et al (2015) Molecular interactions of β-(1→3)-glucans with their receptors. Molecules 20:9745–9766. https://doi.org/10.3390/molecules20069745
Li JG, Liu HX, Cao J et al (2010) PopW of Ralstonia solanacearum, a new two-domain harpin targeting the plant cell wall. Mol Plant Pathol 11:371–381. https://doi.org/10.1111/j.1364-3703.2010.00610.x
Lin T-C, Ishizaka M, Ishii H (2009) Acibenzolar-S-methyl-induced systemic resistance against anthracnose and powdery mildew diseases on cucumber plants without accumulation of phytoalexins. J Phytopathol 157:40–50. https://doi.org/10.1111/j.1439-0434.2008.01448.x
Liu Q, Meng X, Li Y et al (2017) Antibacterial and antifungal activities of spices. Int J Mol Sci 18(6):pii: E1283
Louzoun Zada S, Green KD, Shrestha SK et al (2018) Derivatives of ribosome-inhibiting antibiotic chloramphenicol inhibit the biosynthesis of bacterial cell wall. ACS Infect Dis 4:1121–1129. https://doi.org/10.1021/acsinfecdis.8b00078
Lucas JA, Ramos Solano B, Montes F et al (2009) Use of two PGPR strains in the integrated management of blast disease in rice (Oryza sativa) in Southern Spain. Field Crop Res 114:404–410. https://doi.org/10.1016/j.fcr.2009.09.013
Lymperopoulos P, Msanne J, Rabara R (2018) Phytochrome and phytohormones: working in tandem for plant growth and development. Front Plant Sci 9:1037
Magnuson A (2019) Heterocyst thylakoid bioenergetics. Life 9(1):pii: E13. https://doi.org/10.3390/life9010013
Malve H (2016) Exploring the ocean for new drug developments: marine pharmacology. J Pharm Bioallied Sci 8:83–91
Mancosu N, Snyder R, Kyriakakis G, Spano D (2015) Water scarcity and future challenges for food production. Water 7:975–992. https://doi.org/10.3390/w7030975
Marrone PG (2019) Pesticidal natural products – status and future potential. Pest Manag Sci 75:2325–2340. https://doi.org/10.1002/ps.5433
Martinez M, Santamaria ME, Diaz-Mendoza M et al (2016) Phytocystatins: defense proteins against phytophagous insects and acari. Int J Mol Sci 17(10):pii: E1747
Mc Carthy U, Uysal I, Badia-Melis R et al (2018) Global food security – issues, challenges and technological solutions. Trends Food Sci Technol 77:11–20
McKenzie FC, Williams J (2015) Sustainable food production: constraints, challenges and choices by 2050. Food Secur 7:221–233. https://doi.org/10.1007/s12571-015-0441-1
Miedes E, Vanholme R, Boerjan W, Molina A (2014) The role of the secondary cell wall in plant resistance to pathogens. Front Plant Sci 5:358
Mierziak J, Kostyn K, Kulma A (2014) Flavonoids as important molecules of plant interactions with the environment. Molecules 19:16240–16265. https://doi.org/10.3390/molecules191016240
Morsy NFS (2017) Chemical structure, quality indices and bioactivity of essential oil constituents. In: Active ingredients from aromatic and medicinal plants. InTech, London
Mujeeb F, Bajpai P, Pathak N (2014) Phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of aegle marmelos. Biomed Res Int 2014:1. https://doi.org/10.1155/2014/497606
Nair DG, Weiskirchen R, Al-Musharafi SK (2015) The use of marine-derived bioactive compounds as potential hepatoprotective agents. Acta Pharmacol Sin 36:158–170
Naqvi RZ, Zaidi SSEA, Akhtar KP et al (2017) Transcriptomics reveals multiple resistance mechanisms against cotton leaf curl disease in a naturally immune cotton species, Gossypium arboreum. Sci Rep 7:15880. https://doi.org/10.1038/s41598-017-15963-9
Nazzaro F, Fratianni F, De Martino L et al (2013) Effect of essential oils on pathogenic bacteria. Pharmaceuticals 6:1451–1474
Nita M, Grzybowski A (2016) The role of the reactive oxygen species and oxidative stress in the pathomechanism of the age-related ocular diseases and other pathologies of the anterior and posterior eye segments in adults. Oxidative Med Cell Longev 2016:1
Oka Y, Nacar S, Putievsky E et al (2000) Nematicidal activity of essential oils and their components against the root-knot nematode. Phytopathology 90:710–715. https://doi.org/10.1094/PHYTO.2000.90.7.710
Panche AN, Diwan AD, Chandra SR (2016) Flavonoids: an overview. J Nutr Sci 5:e47
Park SW, Liu PP, Forouhar F et al (2009) Use of a synthetic salicylic acid analog to investigate the roles of methyl salicylate and its esterases in plant disease resistance. J Biol Chem 284:7307–7317. https://doi.org/10.1074/jbc.M807968200
Paul P, Sharma P (2002) Azadirachta indica leaf extract induces resistance in barley against leaf stripe disease. Physiol Mol Plant Pathol 61:3–13. https://doi.org/10.1006/pmpp.2002.0412
Perez-Rosales E, Alcaraz-Meléndez L, Puente ME et al (2018) Endophytic bacteria isolated from wild jojoba [Simmondsia chinensis L. (Schneider)] roots improve in vitro propagation. Plant Cell Tissue Organ Cult 135:515–522. https://doi.org/10.1007/s11240-018-1483-9
Pfaltzgraff A, Brandenburg K, Weindl G (2018) Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds. Front Pharmacol 9:281
Pham JV, Yilma MA, Feliz A et al (2019) A review of the microbial production of bioactive natural products and biologics. Front Microbiol 10:1404. https://doi.org/10.3389/fmicb.2019.01404
Pohlit AM, Lopes NP, Gama RA et al (2011) Patent literature on mosquito repellent inventions which contain plant essential oils – a review. Planta Med 77:598–617
Quarcoo F, Bonsi C, Tackie N (2014) Pesticides, the environment, and human health. In: Pesticides – toxic aspects. InTech, Rijeka, Croatia
Rai M, Pandit R, Gaikwad S, Kövics G (2016) Antimicrobial peptides as natural bio-preservative to enhance the shelf-life of food. J Food Sci Technol 53:3381–3394
Raja A, Gajalakshmi P, Mohamed Mahroop Raja M (2010) Drugs from the natural bio sources for human disease. Int J Pharmacol 6:511–514. https://doi.org/10.3923/ijp.2010.360.363
Rijal J, Regmi R, Ghimire R et al (2018) Farmers’ knowledge on pesticide safety and pest management practices: a case study of vegetable growers in Chitwan, Nepal. Agriculture 8:16. https://doi.org/10.3390/agriculture8010016
Ruiz-López MA, GarcÃa-López PM, RodrÃguez-MacÃas R et al (2010) Mexican wild lupines as a source of quinolizidine alkaloids of economic potential. México
Ruiz-Torres V, Encinar JA, Herranz-López M et al (2017) An updated review on marine anticancer compounds: the use of virtual screening for the discovery of small-molecule cancer drugs. Molecules 22:22. https://doi.org/10.3390/molecules22071037
Samuel VJ, Mahesh AR, Murugan V (2019) Phytochemical and pharmacological aspects of Tephrosia genus: a brief review. J Appl Pharm Sci 9:117–125. https://doi.org/10.7324/JAPS.2019.90317
Sánchez-González L, Vargas M, González-MartÃnez C et al (2011) Use of essential oils in bioactive edible coatings: a review. Food Eng Rev 3:1–16
Sathya A, Vijayabharathi R, Gopalakrishnan S (2017) Plant growth-promoting actinobacteria: a new strategy for enhancing sustainable production and protection of grain legumes. 3 Biotech 7:102
Selim KA, El-Beih AA, Abdel-Rahman TM, El-Diwany AI (2014) Biological evaluation of endophytic fungus, Chaetomium globosum JN711454, as potential candidate for improving drug discovery. Cell Biochem Biophys 68:67–82. https://doi.org/10.1007/s12013-013-9695-4
Shad AA, Ahmad S, Ullah R et al (2014) Phytochemical and biological activities of four wild medicinal plants. Sci World J 2014:1. https://doi.org/10.1155/2014/857363
Shan B, Cai YZ, Brooks JD, Corke H (2008) Antibacterial properties of Polygonum cuspidatum roots and their major bioactive constituents. Food Chem 109:530–537. https://doi.org/10.1016/j.foodchem.2007.12.064
Sharma P, Jha AB, Dubey RS, Pessarakli M (2012) Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions. J Bot 2012:1–26. https://doi.org/10.1155/2012/217037
Simmonds MS, Stevenson PC (2001) Effects of isoflavonoids from Cicer on larvae of Helicoverpa armigera. J Chem Ecol 27:965–977. https://doi.org/10.1023/a:1010339104206
Sivakumar D, Bautista-Baños S (2014) A review on the use of essential oils for postharvest decay control and maintenance of fruit quality during storage. Crop Prot 64:27–37
Sivalingam P, Hong K, Pote J, Prabakar K (2019) Extreme environment streptomyces: potential sources for new antibacterial and anticancer drug leads? Int J Microbiol 2019:1
Sofowora A, Ogunbodede E, Onayade A (2013) The role and place of medicinal plants in the strategies for disease prevention. Afr J Tradit Complement Altern Med 10:210–229
Song Z, Clain J, Iorga BI et al (2015) Saccharomyces cerevisiae-based mutational analysis of the bc1 complex Qo site residue 279 to study the trade-off between atovaquone resistance and function. Antimicrob Agents Chemother 59:4053–4058. https://doi.org/10.1128/AAC.00710-15
Strobel G, Daisy B (2003) Bioprospecting for microbial endophytes and their natural products. Microbiol Mol Biol Rev 67:491–502. https://doi.org/10.1128/mmbr.67.4.491-502.2003
Sugumaran M, Bolton J (1995) Direct evidence for quinone-quinone methide tautomerism during tyrosinase catalyzed oxidation of 4-allylcatechol. Biochem Biophys Res Commun 213:469–474. https://doi.org/10.1006/bbrc.1995.2155
Tan SY, Tatsumura Y (2015) Alexander Fleming (1881–1955): discoverer of penicillin. Singap Med J 56:366–367
Tembo Y, Mkindi AG, Mkenda PA et al (2018) Pesticidal plant extracts improve yield and reduce insect pests on legume crops without harming beneficial arthropods. Front Plant Sci 9:1425. https://doi.org/10.3389/fpls.2018.01425
Termentzi A, Fokialakis N, Leandros Skaltsounis A (2011) Natural resins and bioactive natural products thereof as potential antimicrobial agents. Curr Pharm Des 17:1267–1290. https://doi.org/10.2174/138161211795703807
Thakur M, Sohal BS (2013) Role of elicitors in inducing resistance in plants against pathogen infection: a review. ISRN Biochem 2013:1–10. https://doi.org/10.1155/2013/762412
Thornton PK (2010) Livestock production: recent trends, future prospects. Philos Trans R Soc B Biol Sci 365:2853–2867
Tyśkiewicz K, Konkol M, Kowalski R et al (2019) Characterization of bioactive compounds in the biomass of black locust, poplar and willow. Trees – Struct Funct 33:1235
Vandenborre G, Smagghe G, Van Damme EJM (2011) Plant lectins as defense proteins against phytophagous insects. Phytochemistry 72:1538–1550
Walia S, Saha S, Tripathi V, Sharma KK (2017) Phytochemical biopesticides: some recent developments. Phytochem Rev 16:989–1007
Walsh CT, Wencewicz TA (2014) Prospects for new antibiotics: a molecule-centered perspective. J Antibiot (Tokyo) 67:7–22
Wang X, Radwan MM, Taráwneh AH et al (2013) Antifungal activity against plant pathogens of metabolites from the endophytic fungus Cladosporium cladosporioides. J Agric Food Chem 61:4551–4555. https://doi.org/10.1021/jf400212y
War AR, Paulraj MG, Ahmad T et al (2012) Mechanisms of plant defense against insect herbivores. Plant Signal Behav 7:1306
Xie M, Zhang J, Tschaplinski TJ et al (2018) Regulation of lignin biosynthesis and its role in growth-defense tradeoffs. Front Plant Sci 9:1427. https://doi.org/10.3389/fpls.2018.01427
Xu J (2015) Bioactive natural products derived from mangrove-associated microbes. RSC Adv 5:841–892
Yoon MY, Cha B, Kim JC (2013) Recent trends in studies on botanical fungicides in agriculture. Plant Pathol J 29:1–9. https://doi.org/10.5423/PPJ.RW.05.2012.0072
Yu X, Gao X, Zhu Z et al (2014) Alkaloids from the tribe Bocconieae (Papaveraceae): a chemical and biological review. Molecules 19:13042–13060. https://doi.org/10.3390/molecules190913042
Yuan HY, Saha S, Vandenberg A, Bett KE (2017) Flowering and growth responses of cultivated lentil and wild lens germplasm toward the differences in red to far-red ratio and photosynthetically active radiation. Front Plant Sci 8:386. https://doi.org/10.3389/fpls.2017.00386
Zhang L, Yan C, Guo Q et al (2018) The impact of agricultural chemical inputs on environment: global evidence from informetrics analysis and visualization. Int J Low-Carbon Technol 13:338–352. https://doi.org/10.1093/ijlct/cty039
Zhao H, Ullah H, McNeill MR et al (2019) Inhibitory effects of plant trypsin inhibitors Msti-94 and Msti-16 on Therioaphis trifolii (Monell) (Homoptera: Aphididae) in Alfalfa. Insects 10:154. https://doi.org/10.3390/insects10060154
Zhou X, Liu Y, Huang J et al (2019) High temperatures affect the hypersensitive reaction, disease resistance and gene expression induced by a novel harpin HpaG-Xcm. Sci Rep 9:990. https://doi.org/10.1038/s41598-018-37886-9
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Singh, S., Kumar, V., Datta, S., Dhanjal, D.S., Singh, J. (2020). Plant Disease Management by Bioactive Natural Products. In: Singh, J., Yadav, A. (eds) Natural Bioactive Products in Sustainable Agriculture. Springer, Singapore. https://doi.org/10.1007/978-981-15-3024-1_2
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DOI: https://doi.org/10.1007/978-981-15-3024-1_2
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