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Sperm Selection Techniques for ICSI

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Textbook of Assisted Reproduction

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Abstract

Infertility is a global health problem, affecting an estimated 50 million couples worldwide. It is generally accepted that in 30% of infertile couples, the problem is confined solely to issues related with sperm production, while in 50% of these cases, the problem is a combination of both female and male factors. Since 1992, intracytoplasmic sperm injection (ICSI) has become the technique of hope for many couples suffering from severe male infertility. In order for the ICSI approach to be effective, the preparation and selection of sperm with the highest quality is particularly important. However, current laboratory and clinical results indicate that contemporary methods and approaches are still insufficient to reproducibly prepare and/or select the optimal sperm for successful fertilization, pregnancy, and live birth. In other words, although strong research evidence suggests that the quality of the sperm can predict male fertility potential, association with the main contemporary semen analysis parameters per se is poor or remains largely unclear. This chapter discusses current approaches and their rationale, as well as laboratory and clinical efficacy in selecting the best sperm for a successful ICSI outcome. Based on the available technological knowledge, the future directions in sperm selection for ICSI are also discussed.

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Authors and Affiliations

  1. Bahçeci Fulya IVF Centre, Istanbul, Turkey

    Necati Findikli & Mustafa Bahceci

  2. Faculty of Medicine, Department of Histology and Embryology, Akdeniz University, Antalya, Turkey

    Ciler Celik-Ozenci

  3. British Cyprus IVF Centre, Nicosia, Cyprus

    Munevver Serdarogullari

Authors
  1. Necati Findikli
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  2. Ciler Celik-Ozenci
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  3. Munevver Serdarogullari
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  4. Mustafa Bahceci
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Correspondence to Necati Findikli .

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Editors and Affiliations

  1. Consultant Reproductive Endocrinology & IVF Millennium Medical Center MMC IVF, Dubai Health Care City, Dubai, United Arab Emirates

    Gautam Nand Allahbadia

  2. Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Koç University School of Medicine, Istanbul, Turkey

    Baris Ata

  3. Department of Obstetrics and Gynecology, Wright State University, Boonshoft School of Medicine, Dayton, OH, USA

    Steven R. Lindheim

  4. X&Y Fertility, Leicester, UK

    Bryan J. Woodward

  5. School of Medicine and Dentistry, University of Rochester Medical Center, Newyork, USA

    Bala Bhagavath

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Findikli, N., Celik-Ozenci, C., Serdarogullari, M., Bahceci, M. (2020). Sperm Selection Techniques for ICSI. In: Allahbadia, G.N., Ata, B., Lindheim, S.R., Woodward, B.J., Bhagavath, B. (eds) Textbook of Assisted Reproduction. Springer, Singapore. https://doi.org/10.1007/978-981-15-2377-9_88

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  • DOI: https://doi.org/10.1007/978-981-15-2377-9_88

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  • Publisher Name: Springer, Singapore

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  • Online ISBN: 978-981-15-2377-9

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