Abstract
Many countries are trying to reduce prescription and use of antibiotics. This Chapter outlines a five-year program, implemented in Australia from 2013–2018. The aim was to reduce antibiotic prescribing in primary care by 25% and there was a focus on the management of respiratory infections. Formative evaluation pointed to diagnostic uncertainty and patient expectation as important drivers of prescribing, and a series of key messages and interventions were designed to support both clinicians and patients to use fewer antibiotics. Messaging for health professionals and consumers included the concept that individuals can make a difference and that every prescription matters. Prescribing feedback (with and without audit components), patient action plans and use of media were included in the behavioural interventions. Program acceptance, changes in knowledge and attitudes and changes in prescribing were all trending very positively when the program had an interim evaluation in 2016. This included an overall reduction in antibiotic prescribing of 19%. In addition, ongoing evaluation proved useful in modifying and improving program delivery throughout implementation period.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
Pharmaceutical Benefits Scheme significantly subsidizes prescriptions for the vast majority of medicines in Australia. It is a national insurance scheme for medicines, available to all citizens and it is funded by the Commonwealth Government.
- 2.
See Chap. 2 for additional description of interventions.
- 3.
MedicineInsight practices by 2018 comprised over 600 general practices that voluntarily contributed de-identified data from their clinical management system to the MedicineInsight program for quality improvement purposes. This represents about 10% of all general practices.
References
André, M., Vernby, Å., Berg, J., & Lundborg, C. S. (2010). A survey of public knowledge and awareness related to antibiotic use and resistance in Sweden. Journal of Antimicrobial Chemotherapy, 65(6), 1292–1296. https://doi.org/10.1093/jac/dkq104.
Arnold, S., & Strauss, S. (2005). Interventions to improve antibiotic prescribing practices in ambulatory care (Review). In Cochrane database systematic review. Oxford: Cochrane.
Australia. Department of Health and Aged Care. (2000). The Commonwealth government response to the report of the Joint Expert Technical Advisory Committee on Antibiotic Resistance (JETACAR): Canberra: Australian Government.
Australian Commission on Safety and Quality in Health Care. (2014). Antimicrobial prescribing practice in Australia: Results of the 2013 National Antimicrobial Prescribing Survey. ACSQHC Sydney.
Bhattacharya, A., Hopkins, S., Sallis, A., Budd, E. L., & Ashiru-Oredope, D. (2017). A process evaluation of the UK-wide Antibiotic Guardian campaign: Developing engagement on antimicrobial resistance. Journal of Public Health, 39(2), e40–e47. https://doi.org/10.1093/pubmed/fdw059.
Bjorkman, I., Berg, J., Viberg, N., & Lundborg, C. (2013). Awareness of antibiotic resistance and antibiotic prescribing in UTI treatment: A qualitative study among primary care physicians in Sweden. Scandinavian Journal of Primary Health Care, 31, 50–55.
Bjornsdottir, I., Krintinsson, K., & Holme Hansen, E. (2010). Diagnosing infections: A qualitative view on prescription decisions in general practice over time. Pharmacy World Science, 32, 805–814.
Britt, H., & Harrison, C. (2012). The real story. GP prescribing of antibiotics for respiratory tract infections—From BEACH. Byte from BEACH No.2012; 2. Univeristy of Sydney.
Brookes-Howell, L., Elwyn, G., Hood, K., Wood, F., Cooper, L., Goossens, H., … Butler, C. C. (2012). ‘The body gets used to them’: Patients’ interpretations of antibiotic resistance and the implications for containment strategies. Journal of General Internal Medicine, 27(7), 766–772. https://doi.org/10.1007/s11606-011-1916-1.
Bryce, A., Hay, A. D., Lane, I. F., Thornton, H. V., Wootton, M., & Costelloe, C. (2016). Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: Systematic review and meta-analysis. British Medical Journal, 352, 1939.
Butler, C., Rollnick, S., Pill, R., Maggs-Rapport, F., & Scott, N. (1998). Understanding the culture of prescribing: A qualitative study of general practitioners’ and patients’ perceptions of antibiotics for sore throats. British Medical Journal, 317, 637–642.
Chahwakilian, P., Huttner, B., Schlemmer, B., & Harbarth, S. (2011). Impact of the French campaign to reduce inappropriate ambulatory antibiotic use on the prescription and consultation rates for respiratory tract infections. Journal of Antimicrobial Chemotherapy, 66(12), 2872–2879. https://doi.org/10.1093/jac/dkr387.
Cockburn, J., & Pit, S. (1997). Prescribing behaviour in clinical practice: Patients’ expectations and doctors’ perceptions of patients’ expectations—A questionnaire study. British Medical Journal, 315, 520–523.
Coenen, S., Michiels, B., & Renard, D. (2006). Antibiotic prescribing for acute cough: The effect of perceived patient demand. British Journal of General Practice, 56, 183–190.
Coenen, S., Van Royen, P., Vermeire, E., Hermann, I., & Denekens, J. (2000). Antibiotics for coughing in general practice: A qualitative decision analysis. Family Practice, 17, 380–385.
Ebell, M. H., Lundgren, J., & Youngpairoj, S. (2013). How long does a cough last? Comparing patients’ expectations with data from a systematic review of the literature. Annals of Family Medicine, 11(1), 5–13. https://doi.org/10.1370/afm.1430.
Edgar, T., Boyd, S. D., & Palamé, M. J. (2009). Sustainability for behaviour change in the fight against antibiotic resistance: A social marketing framework. Journal of Antimicrobial Chemotherapy, 63(2), 230–237. https://doi.org/10.1093/jac/dkn508.
Fletcher, S., & Khan, R. (2014). Exploring the management of URTI in general practice: A qualitative study of 34 GPs. Sydney: NPS MedicineWise.
Foisy, M., Martin, B., Domino, F., & Becker, L. A. (2011). The Cochrane Library and the treatment of sore throat in children and adolescents: An overview of reviews. Evidence-Based Child Health: A Cochrane Review Journal, 6(3), 810–823. https://doi.org/10.1002/ebch.771.
Garbutt, J. M., Sterkel, R., Banister, C., Walbert, C., & Strunk, R. C. (2010). Physician and parent response to the FDA advisory about use of over the counter cough and cold medications. Academic pediatrics, 10(1), 64–69. https://doi.org/10.1016/j.acap.2009.07.002.
Gillies, M., Williamson, M., & Carmichael, D. (2015). MedicineInsight. Atrial fibrillation, new oral anticoagulants and antibiotics (Post Market Surveillance Report No. 3).
Grossman, Z., del Torso, S., van Esso, D., Drabik, A., & Sharland, M. (2012). Antibiotic prescribing for upper respiratory tract infections: European primary paediatricians’ knowledge, attitudes and practice. Acta Paediatrica, 101, 935–940.
Gulliford, M. C., Moore, M. V., Little, P., Hay, A. D., Fox, R., Prevost, A. T., … Ashworth, M. (2016). Safety of reduced antibiotic prescribing for self limiting respiratory tract infections in primary care: Cohort study using electronic health records. British Medical Journal, 354. https://doi.org/10.1136/bmj.i3410.
Hutchinson, J., Jelinski, S., Hefferton, D., Desaulniers, G., & Parfrey, P. (2001). Role of diagnostic labelling in antibiotic prescription. Canadian Family Physician, 47, 1217–1224.
Huttner, B., Goossens, H., Verheij, T., & Harbarth, S. (2010). Characteristics and outcomes of public campaigns aimed at improving the use of antibiotics in outpatients in high-income countries. The Lancet Infectious Diseases, 10(1), 17–31. https://doi.org/10.1016/S1473-3099(09)70305-6.
Ingram, J., Cabral, C., Hay, A., Lucas, P., Horwood, J., & TARGET team. (2013). Parents’ information needs, self-efficacy and influences on consulting for childhood respiratory tract infections: A qualitative study. BMC Family Practice, 14, 106.
Khan, R. (2014). Evaluation of the Reducing Antibiotic Resistance (RAR 2012) program (Summary Report). Sydney: NPS MedicineWise.
Kumar, S., Little, P., & Britten, N. (2003). Why do general practitioners prescribe antibiotics for sore throat? Grounded theory interview study. British Medical Journal, 326, 138.
Lim, C., Stuart, R., Buising, K., Friedman, N., Bennett, N., Cheng, A., … Kong, D. (2014). Antimicrobial stewardship in residential aged care facilities: Need and readiness assessment. BMC Infectious Diseases, 14, 410. https://doi.org/10.1186/1471-2334-14-410.
Linder, J., Doctor, J., Friedberg, M., Reyes Nieva, H., Birks, C., Meeker, D., & Fox, C. (2014, July 10). Time of day and the decision to prescribe antibiotics. JAMA Internal Medicine, 174, 2029–2031.
Mangione-Smith, R., Elliott, M., & Stivers, T. (2006). Ruling out the need for antibiotics: Are we sending the right message? Archives of Pediatrics and Adolescent Medicine, 160, 945–952.
McNulty, C., Nichols, T., French, D., Joshi, P., & Butler, C. (2013). Expectations for consultations and antibiotics for respiratory tract infection in primary care: The respiratory tract infection clinical iceberg. British Journal of General Practice, 63, e429–e436.
Norris, P., Churchward, M., Faálau, F., & Vaái, C. (2009). Understanding and use of antibiotics among Samoan people in New Zealand. Journal of Primary Healthcare, 1, 30–35.
Norris, P., Ng, L., Kershaw, V., Hanna, F., Wong, A., Talekar, M., … Cheong, L. (2010). Knowledge and reported use of antibiotics among immigrant ethnic groups in New Zealand. Journal of Immigrant and Minority Health, 12, 107–112.
NPS MedicineWise. (2012). Antibiotic resistance and respiratory tract infections. Program feedback from GPs (Internal document). Sydney: NPS MedicineWise.
NPS MedicineWise. (2014a). Formative research: Antibiotic resistance. A topic specific report covering respiratory tract, urinary tract and skin infections (Internal document). Sydney: NPS MedicineWise.
NPS MedicineWise. (2014b). National consumer survey. Sydney: NPS MedicineWise.
NPS MedicineWise. (2014c). NPS MedicineWise, Antibiotic resistance and respiratory tract infections 2012/2013: Final evaluation report. Sydney. Australia: NPS MedicineWise.
NPS Program Evaluation. (2016). Reducing antibiotic resistance 2014–2016: Evaluation report. Sydney: NPS MedicineWise.
NPS Program Evaluation. (2017). Reducing antibiotic resistance 2016–2017: Evaluation report. Sydney: NPS MedicineWise.
Paluck, E., Katzenstein, D., Frankish, C., Herbert, C., Milner, R., Speert, D., et al. (2001). Prescribing practices and attitudes towards giving children antibiotics. Canadian Family Physician, 47, 521–527.
Panagakou, S. G., Spyridis, Ν., Papaevangelou, V., Theodoridou, K. M., Goutziana, G. P., Theodoridou, M. N., … Hadjichristodoulou, C. S. (2011). Antibiotic use for upper respiratory tract infections in children: A cross-sectional survey of knowledge, attitudes, and practices (KAP) of parents in Greece. BMC Pediatrics, 11, 60. https://doi.org/10.1186/1471-2431-11-60.
Pinto, S., Costa, J., Vaz Carneiro, A., & Fernandes, R. (2013). Analysis of the Cochrane review: Antibiotics for acute otitis media in children. Cochrane Database of Systematic Reviews, 1, CD000219. Acta medica portuguesa, 26(6), 633.
Rousounidis, A., Papaevangelou, V., Hadjipanayis, A., Panagakou, S., Theodoridou, M., Syrogiannopoulos, G., et al. (2011). Descriptive study on parents’ knowledge, attitudes and practices on antibiotic use and misuse in children with upper respiratory tract infections in Cyprus. International Journal of Environmental Research and Public Health, 8, 3246–3262.
Sargent, L., McCullough, A., Del Mar, C., & Lowe, J. (2017). Using theory to explore facilitators and barriers to delayed prescribing in Australia: A qualitative study using the Theoretical Domains Framework and the Behaviour Change Wheel. BMC Family Practice, 18(1), 20. https://doi.org/10.1186/s12875-017-0589-1.
Shaban, R., Cruikshank, M., Christiansen, K., & Committee, Australian Antimicrobial Resistance Standing. (2013). National surveillance and reporting of antimicrobial resistance and antibiotic usage for human health in Australia. Canberra: Australian Government.
Simpson, S., Wood, F., & Butler, C. (2007). General practitioners’perceptions of antimicrobial resistance: A qualitative study. Journal of Antimicrobial Chemotherapy, 59, 292–296.
Singh, M., & Koyfman, A. (2015). Are antibiotics effective in the treatment of acute bronchitis? Annals of Emergency Medicine, 65(5), 566–567. https://doi.org/10.1016/j.annemergmed.2014.11.018.
Stocks, N., & Fahey, T. (2002). The treatment of acute bronchitis by general practitioners in the UK. Results of a cross-sectional postal survey. Australian Family Physician, 31, 676–679.
Strandberg, E., Brorsson, A., Hagstam, C., Troein, M., & Hedin, K. (2013). “I’m Dr Jekyll and Mr Hyde”: Are GP’s antibiotic prescribing patterns contextually dependent? A qualitative focus group study. Scandinavian Journal of Primary Health Care, 31, 158–165.
Wang, K., Seed, P., Schofield, P., Ibrahim, S., & Ashworth, M. (2009). Which practices are high antibiotic prescribers? A cross-sectional analysis. British Journal of General Practice, 59, e315–e320.
World Health Organization. (2015). Global action plan on antimicrobial resistance.
Wu, J., Taylor, D., Ovchinikova, L., Heaney, A., & Morgan, T. (2018). Relationship between antimicrobial-resistance programs and antibiotic dispensing for upper respiratory tract infection: An analysis of Australian data between 2004 and 2015. Journal of International Medical Research, 46, 1326–1338.
Acknowledgements
I wish to acknowledge the work of NPS MedicineWise personnel who designed, conducted and evaluated this program. In particular, I recognize the contribution of Jane London, Clare Weston and Jonathan Dartnell and their teams in designing and delivering the interventions. Suzanne Blogg oversaw the evaluation and Fred Wu undertook the Bayesian analysis to demonstrate changes in prescribing. Kylie Easton led the formative evaluation team that helped elucidate the drivers for change.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Weekes, L.M., Weston, C. (2020). Program to Improve Antibiotic Prescribing in Primary Care. In: Weekes, L. (eds) Improving Use of Medicines and Medical Tests in Primary Care. Springer, Singapore. https://doi.org/10.1007/978-981-15-2333-5_8
Download citation
DOI: https://doi.org/10.1007/978-981-15-2333-5_8
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-15-2332-8
Online ISBN: 978-981-15-2333-5
eBook Packages: MedicineMedicine (R0)