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Exercise and Peripheral Arteriosclerosis

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Physical Exercise for Human Health

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1228))

Abstract

Adaptation of a healthy lifestyle including adequate daily physical activity is shown to reduce 80% of cardiovascular mortality and 40% of cancer-related deaths. A large body of evidence exists proving that this relationship is dose dependent, and even half of the recommended normal physical activity yields significant risk reduction. There has been no medical therapy that would provide such high percentages of reduction in mortality to date. The World Health Organization, therefore, has started an initiative to implement exercise into daily life as a primary prevention measure. Herein, we will focus on the effects of exercise on the vasculature, mainly the peripheral vasculature, in the context of atherosclerotic disease. Exercise has a fundamental role in the pathogenesis, diagnosis, and treatment of atherosclerotic vascular disease. It exerts a protective effect against the development of atherosclerosis irrespective of other cardiovascular risk factors. Additionally, exercise induces changes in vascular hemodynamics helping us to elucidate the presence of obscure vascular involvement. Once again, exercise is the main treatment modality in peripheral arterial disease with accumulating evidence to reduce symptoms and improve both exercise capacity and cardiovascular symptoms.

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  1. Faculty of Medicine, Department of Cardiology, Namik Kemal University, Tekirdag, Turkey

    Demet Ozkaramanli Gur

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  1. Cardiac Regeneration and Ageing Lab Institute of Cardiovascular Sciences School of Life Science, Shanghai University, Shanghai, China

    Junjie Xiao

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Gur, D.O. (2020). Exercise and Peripheral Arteriosclerosis. In: Xiao, J. (eds) Physical Exercise for Human Health. Advances in Experimental Medicine and Biology, vol 1228. Springer, Singapore. https://doi.org/10.1007/978-981-15-1792-1_12

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