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Polyphenol-Loaded Nanomedicines Against Skin Aging

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Abstract

Aging of the skin is an unavoidable process, and different factors are responsible for this process, and the major contributing factor is ultraviolet rays with other factors being dry skin, smoking, lack of nutrients, hormones, etc. Aging of the skin is divided into two types: one is intrinsic aging and other is extrinsic which is also known as photoaging. Spotting, elasticity loss, sagging, wrinkles, and weakening of the skin are generally observed in aged skin. Different approaches are available to averting skin aging. Literature cited about various antioxidants used as cosmeceuticals in skin aging. Natural polyphenols are important phytoconstituents which have scavenging property and form complex with proteins. This property of polyphenols makes it an interesting concept in the treatment of skin aging. Polyphenols lack long-term stability, have low bioavailability rate, are very sensitive to light and heat, have poor solubility, and have bitter and astringent taste. This property limits its use in foods or in medicines. To evade these shortcomings, researchers focus on novel delivery approaches and nanotechnology; that is, nanocarriers are considered to be a favourable approach. In this review, we provide a general demonstration of plant-derived polyphenols and its bioavailability, different types of nanocarriers for pharmaceutical and cosmetology purposes, and product-oriented solutions used in skin aging.

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Author information

Authors and Affiliations

  1. Natural Product Drug Discovery Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, India

    Deepika Singh & Mahfooz ur Rahman

  2. Department of Pharmaceutical Sciences, Shalom Institute of Health & Allied Sciences, SHUATS, Allahabad, Uttar Pradesh, India

    Vikas Kumar

Authors
  1. Deepika Singh
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  2. Mahfooz ur Rahman
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  3. Vikas Kumar
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Editor information

Editors and Affiliations

  1. Department of Pharmaceutical Sciences, Shalom Institute of Health & Allied Sciences, SHUATS, Allahabad, Uttar Pradesh, India

    Mahfoozur Rahman

  2. Nanomedicine Research Lab, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, India

    Sarwar Beg

  3. Department of Pharmaceutical Sciences, Shalom Institute of Health & Allied Sciences, SHUATS, Allahabad, Uttar Pradesh, India

    Vikas Kumar

  4. Nanomedicine Research Lab, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, India

    Farhan Jalees Ahmad

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Singh, D., Rahman, M.u., Kumar, V. (2020). Polyphenol-Loaded Nanomedicines Against Skin Aging. In: Rahman, M., Beg, S., Kumar, V., Ahmad, F. (eds) Nanomedicine for Bioactives . Springer, Singapore. https://doi.org/10.1007/978-981-15-1664-1_10

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