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Swertia spp.: A Potential Source of High-Value Bioactive Components, Pharmacology, and Analytical Techniques

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Bioactive Natural products in Drug Discovery

Abstract

Swertia (Gentianaceae), a diverse genus, is mentioned as a potential herbal drug in Ayurvedic, Unani, and Siddha traditional systems of medicine. Since time immemorial, 70 Swertia species have been used worldwide to cure several health illnesses associated with malaria, cancer, diabetes, inflammation, liver complications, different kinds of fever, etc. Swertia herb is used as the principal component in several marketed herbal/polyherbal formulations. Medicinal usage of Swertia is endorsed to the miscellaneous compounds, viz. xanthones, iridoids, seco-iridoids, and triterpenoids. Swertia is one of the most imperative trade herbs since its market value rises by 10% yearly. A chain of systematic isolation of bioactive compounds and their diverse range of pharmacological effects during the last 10–15 years proved this genus as an industrially important plant. This chapter makes an effort to present the comprehensive assessment on distribution, ethnopharmacology, biological activities, phytochemistry, extraction, and analysis of major bioactive compounds in selected species of Swertia in the past few years, and thus to explore the conventional and nonconventional ways of isolation and evaluation of pharmacologically significant bioactive compounds and to screen out the elite variety of Swertia spp.

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Authors and Affiliations

  1. Department of Biotechnology, Lovely Faculty of Technology and Sciences, Lovely Professional University, Phagwara, Punjab, India

    Prabhjot Kaur & Devendra Kumar Pandey

  2. Department of Biological Sciences, Presidency University (Erstwhile Presidency College), Kolkata, India

    Abhijit Dey

  3. Department of Plant Physiology, Institute of Agriculture Sciences, Banaras Hindu University, Varanasi, UP, India

    Padmanabh Dwivedi

  4. Department of Biochemistry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia

    Tabarak Malik

  5. Department of Botany, Punjabi University, Patiala, India

    R. C. Gupta

Authors
  1. Prabhjot Kaur
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  2. Devendra Kumar Pandey
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  3. Abhijit Dey
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  4. Padmanabh Dwivedi
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  5. Tabarak Malik
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  6. R. C. Gupta
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Corresponding author

Correspondence to Devendra Kumar Pandey .

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Editors and Affiliations

  1. Department of Microbiology, Lovely Professional University, Phagwara, Punjab, India

    Joginder Singh

  2. Department of Plant Pathology and Weed Research, Agricultural Research Organization, The Volcani Centre, Rishon Lezion, Israel

    Vineet Meshram

  3. Department of Biotechnology, Lovely Professional University, Phagwara, Punjab, India

    Mahiti Gupta

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Kaur, P., Pandey, D.K., Dey, A., Dwivedi, P., Malik, T., Gupta, R.C. (2020). Swertia spp.: A Potential Source of High-Value Bioactive Components, Pharmacology, and Analytical Techniques. In: Singh, J., Meshram, V., Gupta, M. (eds) Bioactive Natural products in Drug Discovery. Springer, Singapore. https://doi.org/10.1007/978-981-15-1394-7_4

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