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Interaction of Nanomaterials with Biological Systems

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Introduction to Bionanotechnology

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Abstract

Nanomaterials have been used in biology and medicine. For instance, superparamagnetic iron oxide (Fe3O4) nanoparticles (NPs) have been applied as contrast agents in magnetic resonance imaging (MRI) technology [1, 2]. Materials in range of 50–200 nm could be uptaked into various cell types [3, 4]. Nanoscale materials have been attracted due to their advantages in flexible design, large-surface areas, and easy modification via different ligands [5]. As a result, nanomaterials showed their potential in drug delivery application. When materials at nanoscale as drug carriers, drugs could be efficiently protected from its degradation and metabolism after injection to human body [2]. Nanomaterials could also effectively carry drugs through cell membrane into intracellular environment via different pathways as presented. For cancer treatment purpose, nanoscale materials could be designed for uptaking in only disease targets while avoiding accumulation by healthy cells [6].

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Authors and Affiliations

  1. Department of BioNano Technology, Gachon University, Seongnam-si, Republic of Korea

    Young-Chul Lee

  2. Department of Beauty Design Management, Hansung University, Seoul, Republic of Korea

    Ju-Young Moon

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Lee, YC., Moon, JY. (2020). Interaction of Nanomaterials with Biological Systems. In: Introduction to Bionanotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-15-1293-3_4

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