Histopathology of Breast
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Breast biopsies are one of the most frequently submitted biopsies in any diagnostic surgical pathology practice as breast cancer is by and large the most common cancer among women worldwide. This chapter covers morphologic light microscopic features of most if not all disease entities. Focus is on conventional H&E stained slides, however where necessary immunohistochemical (IHC) stains are also included. Besides unequivocal benign and malignant neoplasms, a major challenge for pathologists is the interpretation of ‘borderline lesions’, where most controversies and difference of opinion arise in this era where most biopsies are small needle core biopsies with limited yield. This requires robust diagnostic criteria laid down by experts to minimize subjectivity. It is hoped that this resource will be helpful for trainees as well as for general diagnostic pathologists as a quick reference in their day-to-day practice and diagnostic challenges.