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Synthesis and Functionalization of S-heterocycles via CDC Reactions

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Abstract

Cross-dehydrogenative coupling has become a powerful tool in organic synthesis. The current developments in the assembly and functionalization of S-heterocycles using this strategy are highlighted in this chapter. The preparation of benzothiophenes, benzothiazoles and cyclic sultams and sulfoxides by intramolecular C(sp2)–H/S–H and C(sp2)–H/C(sp2)–H coupling is discussed. In addition, the coupling of S-heterocycles to arenes and aliphatic compounds is also presented.

Keywords

Benzothiazole Benzothiophene Cross-dehydrogenative coupling Cyclic sulfoxide Cyclic sultam 

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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Department of ChemistryThe University of the West IndiesKingston 7Jamaica

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